Involvement of Anteroventral Periventricular Metastin/Kisspeptin Neurons in Estrogen Positive Feedback Action on Luteinizing Hormone Release in Female Rats

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  1. Diabetes Type 2 and Kisspeptin: Central and Peripheral Sex-Specific Actions
    Monika Dudek, Kamil Ziarniak, Marie-Line Cateau, Laurence Dufourny, Joanna Helena Sliwowska · 2019 · Trends in Endocrinology and Metabolism
  2. Hindbrain Adenosine 5-Triphosphate (ATP)-Purinergic Signaling Triggers LH Surge and Ovulation via Activation of AVPV Kisspeptin Neurons in Rats
    Naoko Inoue, Safiullah Hazim, Hitomi Tsuchida, Yuri Dohi, Ren Ishigaki, Ai Takahashi, Yuki Otsuka, Koki Yamada, Yoshihisa Uenoyama, Hiroko Tsukamura · 2023 · Journal of Neuroscience
  3. Kisspeptin and lactational anestrus: Current understanding and future prospects
    Yoshihisa Uenoyama, Naoko Inoue, Hiroko Tsukamura · 2023 · Peptides
  4. Kiss1-dependent and independent release of luteinizing hormone and testosterone in perinatal male rats
    Jing Chen, Shiori Minabe, Arisa Munetomo, Fumie Magata, Marimo Sato, Sho Nakamura, Masumi Hirabayashi, Yasuhiro Ishihara, Takeshi Yamazaki, Yoshihisa Uenoyama et al. · 2022 · Endocrine Journal
  5. IGF1 gene therapy in middle-aged female rats delays reproductive senescence through its effects on hypothalamic GnRH and kisspeptin neurons
    Franco Juan Cruz Dolcetti, Eugenia Falomir Lockhart, Francisco Acuña, Macarena Lorena Herrera, Sofía Cervellini, Cláudio Gustavo Barbeito, Daniela Grassi, María‐Ángeles Arévalo, María José Bellini · 2022 · Aging
  6. Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats
    Mayuko Nagae, Koki Yamada, Yuki Enomoto, Mari Kometani, Hitomi Tsuchida, Arvinda Panthee, Miku Nonogaki, Nao Matsunaga, Marina Takizawa, Sena Matsuzaki et al. · 2023 · Scientific Reports
  7. Model Systems for Studying Kisspeptin Signalling: Mice and Cells
    William Henry Colledge, Joanne Doran, Hua Mei · 2013 · Advances in experimental medicine and biology
  8. Effects of repeated injection of kisspeptin-10 on the initiation of egg-laying in juvenile quail
    Yingdong Ni, Yanbing Huang, Yunqi Xiao, Jing Wu, Fuyu Qian, Roland Großmann, Ruqian Zhao · 2012 · Animal Reproduction Science
  9. The role of kisspeptin signalling in the regulation of the GnRH-gonadotrophin ovarian axis in mice
    William Henry Colledge, Xavier d’Anglemont de Tassigny · 2010 · Annales d Endocrinologie
  10. The Kiss2/GPR54 system stimulates the reproductive axis in male black porgy, Acanthopagrus schlegelii
    Xilan Ma, Baolei Yuan, Li-Bin Zhou · 2019 · General and Comparative Endocrinology
  11. Reproductive status-dependent dynorphin and neurokinin B gene expression in female Damaraland mole-rats
    Cornelia Voigt, Nigel C. Bennett · 2019 · Journal of Chemical Neuroanatomy
  12. Retinoblastoma binding protein 7 is involved in Kiss1 mRNA upregulation in rodents
    Kei Horihata, Naoko Inoue, Yoshihisa Uenoyama, Kei‐ichiro Maeda, Hiroko Tsukamura · 2020 · Journal of Reproduction and Development
  13. Estrogen-Regulated Lateral Septal Kisspeptin Neurons Abundantly Project to GnRH Neurons and the Hypothalamic Supramammillary Nucleus
    Soma Szentkirályi-Tóth, Balázs Göcz, Szabolcs Takács, Miklós Sárvári, Imre Farkas, Katalin Skrapits, Éva Rumpler, Szilárd Póliska, Gergely Rácz, András Matolcsy et al. · 2025 · Journal of Neuroscience
  14. Norepinephrine modulation of heat dissipation in female rats lacking estrogen
    Cristina S. Fonseca, Nayara S. S. Aquino, Gleisy Kelly Neves Gonçalves, Lucas Rios Drummond, Laisa Taline Magalhaes Hipolito, Juneo Freitas Silva, Kaoma Stephani da Costa Silva, Patrícia Costa Henriques, Talita Emanuela Domingues, Ana Cristina Rodrigues Lacerda et al. · 2022 · Journal of Neuroendocrinology
  15. Inhibitory role of the serotonergic system on estrogen receptor α expression in the female rat hypothalamus
    Hiroyuki Ito, Yuji Shimogawa, Daisuke Kohagura, Tetsuji Moriizumi, Korehito Yamanouchi · 2014 · Neuroscience Letters
  16. Interactions between Kisspeptin Neurons and Hypothalamic Tuberoinfundibular Dopaminergic Neurons in Aged Female Rats
    Kinuyo Iwata, Masaaki Ikehara, Yuyu Kunimura, Hitoshi Ozawa · 2016 · ACTA HISTOCHEMICA ET CYTOCHEMICA
  17. The KISS1 gene overexpression as a potential molecular marker for cervical cancer cells
    Keiko Taniguchi‐Ponciano, Rosa María Ribas‐Aparicio, Daniel Marrero–Rodríguez, Hugo Arreola, Víctor Huerta-Padilla, Nancy Muñoz, Laura Gómez-Ortiz, Gustavo Ponce-Navarrete, Miriam Rodríguez-Esquivel, Mónica Mendoza-Rodríguez et al. · 2018 · Cancer Biomarkers
  18. Role of kisspeptin and Kiss1R in the regulation of prolactin gene expression in rat somatolactotroph GH3 cells
    Tomomi Hara, Haruhiko Kanasaki, Tuvshintugs Tumurbaatar, Aki Oride, Hiroe Okada, Satoru Kyo · 2018 · Endocrine
  19. Sheep as a model for neuroendocrinology research
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  20. Suprachiasmatic nucleus and vagus nerve trigger preovulatory LH and ovulation
    Elizabeth Vieyra, Julio C García, Hugo Alberto Zarco-Juarez, Rosa Linares, Gabriela Rosas, Deyra A. Ramírez, Andrea Chaparro, Julieta A. Espinoza, Roberto Domı́nguez, Leticia Morales‐Ledesma · 2022 · Reproduction
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    Takeshi Iwasa, Hiroki Noguchi, Hidenori Aoki, Kou Tamura, Takaaki Maeda, Asuka Takeda, Maimi Uchishiba, Ryosuke Arakaki, Saki Minato, Shuhei Kamada et al. · 2022 · Endocrine Journal
  22. Expression and Regulation of Dickkopf2 During Periimplantation in Mice
    Ying Zhang, Sha Peng, Haibin Kuang, Qi Chen, Shuang Liu, Li Zhang, Enkui Duan · 2009 · Journal of Reproduction and Development
  23. Integrated analyses using medaka as a powerful model animal toward understanding various aspects of reproductive regulation
    Chie Umatani, Mikoto Nakajo, Daichi Kayo, Yoshitaka Oka, Shinji Kanda · 2021 · Elsevier eBooks
  24. Puberté, fertilité et maladies chroniques
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  25. Hypothalamus-Pituitary-Gonadal Axis: It is Time for Revision
    Byron Asimakopoulos · 2012 · Human Genetics & Embryology
  26. JMJD3 Is Crucial for the Female AVPV RIP-Cre Neuron-Controlled Kisspeptin–Estrogen Feedback Loop and Reproductive Function
    Anying Song, Shujun Jiang, Qinghua Wang, Jianghuan Zou, Zhaoyu Lin, Xiang Gao · 2017 · Endocrinology
  27. Involvement of the kisspeptin system in regulation of sexual behaviors in medaka
    Mikoto Nakajo, Shinji Kanda, Yoshitaka Oka · 2024 · iScience
  28. Region-specific changes in brain kisspeptin receptor expression during estrogen depletion and the estrous cycle
    Saeko Ozaki, Shimpei Higo, Kinuyo Iwata, Hidehisa Saeki, Hitoshi Ozawa · 2019 · Histochemistry and Cell Biology
  29. Sexually dimorphic gene expression and neurite sensitivity to estradiol in fetal arcuate Kiss1 cells
    Caroline Alfaïa, V. Robert, Kévin Poissenot, Yves Le Vern, Daniel Guillaume, Shel‐Hwa Yeo, William Henry Colledge, Isabelle Franceschini · 2019 · Journal of Endocrinology
  30. Gonadotrophin‐releasing hormone and kisspeptin: It takes two to tango
    Anne Hélène Duittoz, Xavier Cayla, Renaud Fleurot, Jonas Lehnert, Anmar Khadra · 2021 · Journal of Neuroendocrinology
  31. Estradiol and progesterone-induced lordosis behavior is modulated by both the Kisspeptin receptor and melanin-concentrating hormone in estradiol benzoate-primed rats
    Oscar González‐Flores, James G. Pfaus, Ailyn Luna‐Hernández, Omar Montes-Narváez, Raymundo Domínguez‐Ordóñez, Miriam B. Tecamachaltzi-Silvarán, Marcos García‐Juárez · 2022 · Hormones and Behavior
  32. Short-term depletion of plasma estrogen affects hypothalamic kisspeptin-neurokinin B-dynorphin A neurons, gonadotrophs, and pulsatile luteinizing hormone secretion in female rats
    Kinuyo Iwata, Risako Ogata, Marimo Sato, Fuko Matsuda, Hirotaka Ishii, Hitoshi Ozawa · 2022 · Peptides
  33. Design and synthesis of fluorescent probes for GPR54
    Masato Kaneda, Ryosuke Misu, Hiroaki Ohno, Akira Hirasawa, Nahoko Ieda, Yoshihisa Uenoyama, Hiroko Tsukamura, Kei‐ichiro Maeda, Shinya Oishi, Nobutaka Fujii · 2014 · Bioorganic & Medicinal Chemistry
  34. Effects of the Fertility Drugs Clomiphene Citrate and Letrozole on Kiss-1 Expression in Hypothalamic Kiss-1-Expressing Cell Models
    Aki Oride, Haruhiko Kanasaki, Tuvshintugs Tumurbaatar, Zolzaya Tumurgan, Hiroe Okada, Tomomi Hara, Satoru Kyo · 2020 · Reproductive Sciences
  35. Chronic estradiol exposure suppresses luteinizing hormone surge without affecting kisspeptin neurons and estrogen receptor alpha in anteroventral periventricular nucleus
    Yuyu Kunimura, Kinuyo Iwata, Hirotaka Ishii, Hitoshi Ozawa · 2023 · Biology of Reproduction
  36. Toxicity of Radiation
    Kausik Ray · 2017 · Elsevier eBooks
  37. Neonatal Aromatase Inhibition Blocked Defeminization of AVPV Kiss1 Neurons and LH Surge-Generating System in Male Rats
    Koki Yamada, Tetsuya Mano, Safiullah Hazim, Marina Takizawa, Naoko Inoue, Yoshihisa Uenoyama, Hiroko Tsukamura · 2024 · Endocrinology
  38. Cellular and molecular mechanisms of action of ovarian steroid hormones II: Regulation of sexual behavior in female rodents.
    James G. Pfaus, Marcos García‐Juárez, Raymundo Domínguez Ordóñez, Miriam B. Tecamachaltzi-Silvarán, Rosa Angélica Lucio, Oscar González‐Flores · 2024 · Neuroscience & Biobehavioral Reviews
  39. Prior attenuation of KiSS1/GPR54 signaling in the anteroventral periventricular nucleus is a trigger for the delayed effect induced by neonatal exposure to 17alpha-ethynylestradiol in female rats
    Ryohei Ichimura, Miwa Takahashi, Tomomi Morikawa, Kaoru Inoue, Jun Maeda, Kento Usuda, Makoto Yokosuka, Gen Watanabe, Midori Yoshida · 2015 · Reproductive Toxicology
  40. Estrogenic regulation of Kiss1 mRNA variants in Hatano rats
    Yasuyuki Horii, Sandun L. Dalpatadu, Tomoko Soga, Ryo Ohta, Gen Watanabe, Kazuyoshi Taya, Ishwar S. Parhar · 2012 · General and Comparative Endocrinology
  41. Hypothalamic KiSS1/GPR54 Gene Expressions and Luteinizing Hormone Plasma Secretion in Morphine Treated Male Rats.
    Homayoun Khazali, Fariba Mahmoudi, Mahyar Janahmadi · 2018 · Europe PMC (PubMed Central)
  42. Defeminization of Brain Functions by a Single Injection of Estrogen Receptor α or β Agonist in Neonatal Female Rats
    Moeko Kanaya, Korehito Yamanouchi · 2012 · Neuroendocrinology
  43. Evidence for a role of KISS-1/GPR54 system in decreased luteinizing hormone (LH) secretion in fasted prepubertal ewes
    Jun Wang · 2012 · AFRICAN JOURNAL OF BIOTECHNOLOGY
  44. Fetal/perinatal Programming Causing Sexual Dimorphism of the Kisspeptin– GnRH Neuronal Network
    Hiroko Tsukamura, Kei‐ichiro Maeda, Yoshihisa Uenoyama · 2018
  45. Identification of differentially expressed genes associated with precocious puberty by suppression subtractive hybridization in goat pituitary tissues
    Yufang Liu, Guiling Cao, Yujing Xie, Mingxing Chu · 2021 · Animal Biotechnology
  46. Neuroendocrine mechanisms of reproductive dysfunctions in undernourished condition
    Takeshi Iwasa, Yuri Yamamoto, Hiroki Noguchi, Asuka Takeda, Saki Minato, Shuhei Kamada, Junki Imaizumi, Tomohiro Kagawa, Atsuko Yoshida, Takako Kawakita et al. · 2022 · Journal of obstetrics and gynaecology research
  47. The Hypothalamus and Pituitary Gland Regulate Reproduction and Are Involved in the Development of Polycystic Ovary Syndrome
    B H Long, Xipeng Liao, Xin Liang · 2025 · Neuroendocrinology
  48. The role of kisspeptin signaling in reproduction of ruminants.
    Thuchadaporn Chaikhun, Pongsiwa Sotthibandhu, Siriwat Suadsong · 2013 · The Thai Journal of Veterinary Medicine
  49. Research progress in molecular mechanism of animal seasonal reproduction
    Dongwei Huang, Mingxing Chu · 2011 · Hereditas (Beijing)
  50. Reciprocal Changes in Voltage-Gated Potassium and Subthreshold Inward Currents Help Maintain Firing Dynamics of AVPV Kisspeptin Neurons during the Estrous Cycle
    J. Rudolph Starrett, Richard Anthony DeFazio, Suzanne M. Moenter · 2021 · eNeuro
  51. Serum kisspeptin levels mainly depend on ovarian expression of Kiss1 mRNA in female rats
    Ahreum Kwon, Ji Young Eom, Woo Jung Lee, Han Saem Choi, Kyungchul Song, Junghwan Suh, Hyun Wook Chae, Ho-Seong Kim · 2022 · Frontiers in Physiology
  52. The GnRH Pulse Generator
    Pasha Grachev, Robert L. Goodman · 2016 · AIMS Medical Science
  53. Morphine attenuates testosterone response to central injection of kisspeptin in male rats.
    Fariba Mahmoudi, Homayoun Khazali, Mahyar Janahmadi · 2014 · PubMed Central
  54. RP3V kisspeptin neurons mediate neuroprogesterone induction of the luteinizing hormone surge in female rat
    Lauren K. Delhousay, Timbora Chuon, Melinda Mittleman-Smith, Paul E. Micevych, Kevin Sinchak · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  55. Epigenomic control of gonadotrophin‐releasing hormone neurone development and hypogonadotrophic hypogonadism
    Megan L. Linscott, Wilson C. J. Chung · 2020 · Journal of Neuroendocrinology
  56. Variation in Hypothalamic GnIH Expression and Its Association with GnRH and Kiss1 during Pubertal Progression in Male Rhesus Monkeys (Macaca mulatta)
    Hira Zubair, Muhammad Saqib, Muhammad Noman Khan, Shazia Shamas, Shahzad Irfan, Muhammad Shahab · 2022 · Animals
  57. Kisspeptin induces Kiss-1 and GnRH gene expression in mHypoA-55 hypothalamic cell models: Involvement of the ERK and PKA signaling pathways
    Tuvshintugs Tumurbaatar, Haruhiko Kanasaki, Susdiaman S. Yacca, Zhuoma Cairang, Zolzaya Tumurgan, Aki Oride, Hiroe Okada, Satoru Kyo · 2023 · General and Comparative Endocrinology
  58. Postnatal Development and Maintenance of Functional Pituitary Gonadotrophs Is Dependent on PI4-Kinase A
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  59. Kisspeptin administration may promote precopulatory behavior in male rats independently or supplementally to testosterone and contribute to proceptive behavior in female partners, reducing mating failure
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  60. Participation of kisspeptin, progesterone, and GnRH receptors on lordosis behavior induced by kisspeptin
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  71. Parallel expression patterns of NR4A nuclear receptor family genes in the pituitary gland of proestrus rats
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  76. Circadian transcription factor Dbp promotes rat calvarial osteoprogenitors osteogenic differentiation through Kiss1/GnRH/E2 signaling pathway loop
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  77. Thyrotropin-releasing hormone stimulates NR4A3 expression in the pituitary thyrotrophs of proestrus rats
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  78. Differential regulation of Kiss1 gene expression by oestradiol in the hypothalamus of the female Damaraland mole-rat, an induced ovulator
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    Marco Bonomi, Valeria Vezzoli, Anna Maria Cariboni · 2017 · Endocrinology
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  88. Kisspeptin made in the preoptic area is required for normal estradiol-induced LH surges and optimal fertility in females
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  90. Evaluation of the Hypothalamic Kisspeptin System throughout the Estrous Cycle in Gilts
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  92. Absence of sex differences in diabetes-induced suppression of KNDy neurons in rats
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  93. Effects of Short Term Administration of Genistein on Hypothalamic and Anterior Pituitary Hormones in Ovariectomized Gilts
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  95. Mystic Effects of Kisspeptin in Reproduction of Livestock
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  97. Roles of intracerebral activin, inhibin, and follistatin in the regulation of Kiss-1 gene expression: Studies using primary cultures of fetal rat neuronal cells
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  98. Glucocorticoids Regulate Kisspeptin Neurons during Stress and Contribute to Infertility and Obesity in Leptin-Deficient Mice
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  99. Neuroendocrine Regulation of Puberty
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  100. Role of membrane estrogen receptor alpha on the negative feedback of estrogens on luteinizing hormone secretion
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