The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Underlying diseases in syncope of children in China
Open accessAbstract
BACKGROUND: Syncope accounts for about 1-2% of emergency department visits, but the etiology in many patients with syncope is unclear. Recently, with the use of the head-up tilt test (HUT), the number of patients with unexplained syncope (UPS) has been decreasing; however, the spectrum of underlying diseases of syncope in children is unclear. This retrospective study aimed to analyze the spectrum of underlying diseases in children with syncope. MATERIAL/METHODS: This multi-center clinical study consisted of 888 children (417 males, 471 females, aged 5-18 yrs, median age 12.0±3.0 yrs) with syncope who came from Beijing city, Hunan province, Hubei province and Shanghai from August 1999 to March 2009. The clinical and laboratory data of children were studied and the spectrum of underlying diseases in children with syncope was analyzed. RESULTS: In 888 children with syncope, 175 (19.7%) had vasovagal syncope (VVS) with vasoinhibitory response, 35 (3.9%) had VVS with cardioinhibitory response, 73 (8.2%) had VVS with mixed response, 286 (32.2%) had postural orthostatic tachycardia syndrome (POTS), 19 (2.1%) had orthostatic hypotension, 7 (0.9%) had situational syncope, 13 (1.5%) had cardiogenic syncope, and 280 (31.5%) had unexplained syncope. CONCLUSIONS: The data suggest that neurally-mediated syncope was the most common cause in children with syncope. POTS and VVS were the most common hemodynamic patterns of neurally-mediated syncope.
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Syncope accounts for 3% of all pediatric ED visits.
“By 18 years of age, it is estimated that 30% to 50% of children experience at least 1 fainting episode, and syncope accounts for 3% of all pediatric ED visits (617–622).”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [620]
The Background and Discussion (page not available) say syncope accounts for about 1–2% of emergency department visits, not 3%. The Discussion also reports that syncope and pre-syncope together accounted for 0.8% of visits in a pediatric emergency care unit. (LLM, conf=0.88)
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Experimental — accuracy not yet measuredBy 18 years of age, an estimated 30% to 50% of children experience at least 1 fainting episode.
“By 18 years of age, it is estimated that 30% to 50% of children experience at least 1 fainting episode, and syncope accounts for 3% of all pediatric ED visits (617–622).”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [620]
The Results describe 888 children aged 5–18 who already had syncope; they do not estimate how many children faint by age 18. The Discussion calls pediatric syncope common but gives no 30%–50% lifetime estimate. Searches for that range and for lifetime prevalence by age 18 found no supporting passage. Page numbers were unavailable in our copy. (LLM, conf=0.77)
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Citations
Cites
A Prospective Evaluation and Follow-up of Patients with Syncope
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The efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope
Qingyou, Z., Junbao, D., & Chaoshu, T. (2006) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2006.07.031 · Cited by 108
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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.03.004 · Cited by 478
2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.03.003 · Cited by 327
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.03.002 · Cited by 155
Metadata
- Authors
- Chen, L., Wang, C., Wang, H., Tian, H., Tang, C., Jin, H., & Du, J.
- Affiliations
- Peking University (CN)
- Department of Pediatrics, Zhongnan University Xiangya 2nd Hospital, Hunan Province, China
- Huazhong University of Science and Technology (CN)
- Fudan University (CN)
- Corresponding author
- Du, Junbao
- Venue
- Medical Science Monitor
- Published
- 2011
- Volume
- 17
- Issue
- 6
- Pages
- PH49-PH53
- ISSN
- 1234-1010 (ISSN-L)
- PMC
- PMC3539540
- OpenAlex
- W1993065730
- Cited by
- 49
- References
- 2
- Citations by year
- 2026: 2 · 2024: 6 · 2023: 4 · 2022: 5 · 2021: 2 · 2020: 5 · 2019: 1 · 2018: 6 · 2017: 6 · 2016: 3 · 2014: 4 · 2013: 3 · 2012: 2
- FWCI
- 2.95
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- Medical Science Monitor (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- syncope, pediatric syncope, unexplained syncope, vasovagal syncope, postural orthostatic tachycardia syndrome, neurally mediated syncope, orthostatic hypotension, situational syncope, cardiac syncope, head-up tilt
- MeSH terms
- Adolescent, Child, China, Female, Humans, Male, Syncope
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