The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The value of plants used in traditional medicine for drug discovery.
Open accessAbstract
In this review we describe and discuss several approaches to selecting higher plants as candidates for drug development with the greatest possibility of success. We emphasize the role of information derived from various systems of traditional medicine (ethnomedicine) and its utility for drug discovery purposes. We have identified 122 compounds of defined structure, obtained from only 94 species of plants, that are used globally as drugs and demonstrate that 80% of these have had an ethnomedical use identical or related to the current use of the active elements of the plant. We identify and discuss advantages and disadvantages of using plants as starting points for drug development, specifically those used in traditional medicine.
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Cites
The influence of natural products upon drug discovery (Antiquity to late 1999)
Newman, D. J., Cragg, G. M., & Snader, K. M. (2000) · Natural Product Reports · doi:10.1039/a902202c · Cited by 1,293
Cited by
Extraction, Isolation And Characterization Of Bioactive Compounds From Plants’ Extracts
Sasidharan, S., Chen, Y., Saravanan, D., Sundram, K., & Latha, L. (2010) · African Journal of Traditional, Complementary and Alternative Medicines · doi:10.4314/ajtcam.v8i1.60483 · Cited by 1,456
Ayurveda and Traditional Chinese Medicine: A Comparative Overview
Patwardhan, B., Warude, D., Pushpangadan, P., & Bhatt, N. (2005) · Evidence-Based Complementary and Alternative Medicine · doi:10.1093/ecam/neh140 · Cited by 856
Neag, M. A., Mocan, A., Echeverría, J., Pop, R. M., Bocsan, C. I., Crişan, G., & Buzoianu, A. D. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00557 · Cited by 562
Nothias, L.-F., Nothias-Esposito, M., da Silva, R., Wang, M., Protsyuk, I., Zhang, Z., Sarvepalli, A., Leyssen, P., Touboul, D., Costa, J., et al. (2018) · Journal of Natural Products · doi:10.1021/acs.jnatprod.7b00737 · Cited by 433
An Overview of the Evidence and Mechanisms of Herb–Drug Interactions
Fasinu, P. S., Bouic, P. J., & Rosenkranz, B. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00069 · Cited by 221
Metadata
- Authors
- Fabricant, D. S., & Farnsworth, N. R.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2001-03
- Volume
- 109
- Issue
- suppl 1
- Pages
- 69-75
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W2123409005
- Cited by
- 2,038
- References
- 1
- FWCI
- 7.06
- Type
- journal article
- Language
- en
- Open access
- gold
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- Fabricant, D. S., & Farnsworth, N. R. (2001). The value of plants used in traditional medicine for drug discovery. Environmental Health Perspectives. https://doi.org/10.1289/ehp.01109s169
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
