The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Effect of Early Life Exposure to Air Pollution on Development of Childhood Asthma
Open accessAbstract
Abstract Background There is increasing recognition of the importance of early environmental exposures in the development of childhood asthma. Outdoor air pollution is a recognized asthma trigger, but it is unclear whether exposure influences incident disease. We investigated the effect of exposure to ambient air pollution in utero and during the first year of life on risk of subsequent asthma diagnosis in a population-based nested case–control study. Methods We assessed all children born in southwestern British Columbia in 1999 and 2000 (n = 37,401) for incidence of asthma diagnosis up to 3–4 years of age using outpatient and hospitalization records. Asthma cases were age- and sex-matched to five randomly chosen controls from the eligible cohort. We estimated each individual’s exposure to ambient air pollution for the gestational period and first year of life using high-resolution pollution surfaces derived from regulatory monitoring data as well as land use regression models adjusted for temporal variation. We used logistic regression analyses to estimate effects of carbon monoxide, nitric oxide, nitrogen dioxide, particulate matter ≤ 10 μm and ≤ 2.5 μm in aerodynamic diameter (PM10 and PM2.5), ozone, sulfur dioxide, black carbon, woodsmoke, and proximity to roads and point sources on asthma diagnosis. Results A total of 3,482 children (9%) were classified as asthma cases. We observed a statistically significantly increased risk of asthma diagnosis with increased early life exposure to CO, NO, NO2, PM10, SO2, and black carbon and proximity to point sources. Traffic-related pollutants were associated with the highest risks: adjusted odds ratio = 1.08 (95% confidence interval, 1.04–1.12) for a 10-μg/m3 increase of NO, 1.12 (1.07–1.17) for a 10-μg/m3 increase in NO2, and 1.10 (1.06–1.13) for a 100-μg/m3 increase in CO. These data support the hypothesis that early childhood exposure to air pollutants plays a role in development of asthma.
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Asthma and Wheezing in the First Six Years of Life
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A review and evaluation of intraurban air pollution exposure models
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Self-citationTraffic, Susceptibility, and Childhood Asthma
McConnell, R., Berhane, K., Yao, L., Jerrett, M., Lurmann, F., Gilliland, F., Künzli, N., Gauderman, J., Avol, E., Thomas, D., et al. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8594 · Cited by 635
A Cohort Study of Traffic-Related Air Pollution Impacts on Birth Outcomes
Brauer, M., Lencar, C., Tamburic, L., Koehoorn, M., Demers, P., & Karr, C. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10952 · Cited by 605
Self-citationAir pollution and development of asthma, allergy and infections in a birth cohort
Brauer, M., Hoek, G., Smit, H. A., de Jongste, J. C., Gerritsen, J., Postma, D. S., Kerkhof, M., & Brunekreef, B. (2007) · European Respiratory Journal · doi:10.1183/09031936.00083406 · Cited by 581
Self-citationAtopic diseases, allergic sensitization, and exposure to traffic-related air pollution in children.
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Childhood Asthma and Exposure to Traffic and Nitrogen Dioxide
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Cited by
Outdoor air pollution and asthma.
Guarnieri, M., & Balmes, J. R. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60617-6 · Cited by 1,889
Air pollution and its effects on the immune system
Glencross, D. A., Ho, T.-R., Camiña, N., Hawrylowicz, C. M., & Pfeffer, P. E. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.01.179 · Cited by 726
Kabisch, N., van den Bosch, M., & Lafortezza, R. (2017) · Environmental Research · doi:10.1016/j.envres.2017.08.004 · Cited by 482
Motor vehicle air pollution and asthma in children: A meta-analysis
Gasana, J., Dillikar, D., Mendy, A., Forno, E., & Ramos Vieira, E. (2012) · Environmental Research · doi:10.1016/j.envres.2012.05.001 · Cited by 296
Health impacts of anthropogenic biomass burning in the developed world
Sigsgaard, T., Forsberg, B., Annesi-Maesano, I., Blomberg, A., Bølling, A., Boman, C., Bønløkke, J., Brauer, M., Bruce, N., Héroux, M.-E., et al. (2015) · European Respiratory Journal · doi:10.1183/13993003.01865-2014 · Cited by 266
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Metadata
- Authors
- Clark, N. A., Demers, P. A., Karr, C. J., Koehoorn, M., Lencar, C., Tamburic, L., & Brauer, M.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-02
- Volume
- 118
- Issue
- 2
- Pages
- 284-290
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W2015737793
- Cited by
- 560
- References
- 48
- FWCI
- 19.24
- Type
- journal article
- Language
- en
- Open access
- gold
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