The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Assessing Exposure and Health Consequences of Chemicals in Drinking Water: Current State of Knowledge and Research Needs
Open accessAbstract
BACKGROUND: Safe drinking water is essential for well-being. Although microbiological contamination remains the largest cause of water-related morbidity and mortality globally, chemicals in water supplies may also cause disease, and evidence of the human health consequences is limited or lacking for many of them. OBJECTIVES: We aimed to summarize the state of knowledge, identify gaps in understanding, and provide recommendations for epidemiological research relating to chemicals occurring in drinking water. DISCUSSION: Assessing exposure and the health consequences of chemicals in drinking water is challenging. Exposures are typically at low concentrations, measurements in water are frequently insufficient, chemicals are present in mixtures, exposure periods are usually long, multiple exposure routes may be involved, and valid biomarkers reflecting the relevant exposure period are scarce. In addition, the magnitude of the relative risks tends to be small. CONCLUSIONS: Research should include well-designed epidemiological studies covering regions with contrasting contaminant levels and sufficient sample size; comprehensive evaluation of contaminant occurrence in combination with bioassays integrating the effect of complex mixtures; sufficient numbers of measurements in water to evaluate geographical and temporal variability; detailed information on personal habits resulting in exposure (e.g., ingestion, showering, swimming, diet); collection of biological samples to measure relevant biomarkers; and advanced statistical models to estimate exposure and relative risks, considering methods to address measurement error. Last, the incorporation of molecular markers of early biological effects and genetic susceptibility is essential to understand the mechanisms of action. There is a particular knowledge gap and need to evaluate human exposure and the risks of a wide range of emerging contaminants. CITATION: Villanueva CM, Kogevinas M, Cordier S, Templeton MR, Vermeulen R, Nuckols JR, Nieuwenhuijsen MJ, Levallois P. 2014. Assessing exposure and health consequences of chemicals in drinking water: current state of knowledge and research needs. Environ Health Perspect 122:213–221; http://dx.doi.org/10.1289/ehp.1206229
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Challenge of Micropollutants in Aquatic Systems
Schwarzenbach, R. P., Escher, B. I., Fenner, K., Hofstetter, T. B., Johnson, C. A., von Gunten, U., & Wehrli, B. (2006) · Science · doi:10.1126/science.1127291 · Cited by 3,704
RICHARDSON, S., PLEWA, M., WAGNER, E., SCHOENY, R., & DEMARINI, D. (2007) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2007.09.001 · Cited by 3,317
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
Vandenberg, L. N., Colborn, T., Hayes, T. B., Heindel, J. J., Jacobs, D. R., Lee, D.-H., Shioda, T., Soto, A. M., vom Saal, F. S., Welshons, W. V., et al. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1050 · Cited by 3,209
Paerl, H. W., & Huisman, J. (2008) · Science · doi:10.1126/science.1155398 · Cited by 2,854
Wild, C. P. (2005) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0456 · Cited by 2,562
Water Analysis: Emerging Contaminants and Current Issues
Richardson, S. D., & Ternes, T. A. (2014) · Analytical Chemistry · doi:10.1021/ac500508t · Cited by 2,144
Environmental fate and toxicity of ionic liquids: A review
Thuy Pham, T. P., Cho, C.-W., & Yun, Y.-S. (2010) · Water Research · doi:10.1016/j.watres.2009.09.030 · Cited by 1,576
IARC (International Agency for Research on Cancer)
Toporcov, T. N., & Filho, V. W. (2018) · Cited by 1,178
Summer heatwaves promote blooms of harmful cyanobacteria
JÖHNK, K. D., HUISMAN, J., SHARPLES, J., SOMMEIJER, B., VISSER, P. M., & STROOM, J. M. (2008) · Global Change Biology · doi:10.1111/j.1365-2486.2007.01510.x · Cited by 1,100
Silva, E., Rajapakse, N., & Kortenkamp, A. (2002) · Environmental Science & Technology · doi:10.1021/es0101227 · Cited by 912
Research works printed but not linked: 9
- Cantor, 2010, Carcinogens in drinking water: the epidemiologic evidence., Rev Environ Health, 25, 9, 10.1515/REVEH.2010.25.1.9 · doi:10.1515/reveh.2010.25.1.9
- Cantor, 2007, Arsenic, internal cancers, and issues in inference from studies of low-level exposures in human populations., Toxicol Appl Pharmacol, 222, 252, 10.1016/j.taap.2007.01.026 · doi:10.1016/j.taap.2007.01.026
- Cragle DL, Shy CM, Struba RJ, Siff EJ., 1985, A case-control study of colon cancer and water chlorination in North Carolina. In: Water Chlorination: Chemistry, Environmental Impact and Health Effects, Vol. 5 (Jolley RL, Bull RJ, Davis WP, Katz S, Roberts MH Jr, Jakobs VA, eds)
- Ericson Jogsten I. 2011. Assessment of Human Exposure to Per- and Polyfluorinated Compounds (PFCs). Exposure through Food, Drinking Water, House Dust and Indoor Air [PhD Dissertation].Örebro, Sweden:Örebro University.
- Newcombe, 2012, Cyanobacteria: impacts of climate change on occurrence, toxicity and water quality management., Water Res, 46, 1347, 10.1016/j.watres.2011.12.047 · doi:10.1016/j.watres.2011.12.047
- Rogers, 2002, Acute and subchronic mammalian toxicity of naphthenic acids from oil sands tailings., Toxicol Sci, 66, 347, 10.1093/toxsci/66.2.347 · doi:10.1093/toxsci/66.2.347
- Sato M, Takigami H, Hayakawa K, Sakai S. 2010. Water-quality monitoring technique for dioxins during dredging using on-site solid phase extraction with graphitic carbon and analysis with DR-CALUX. J Environ Sci Health A Tox Hazard Subst Environ Eng 45:867–874. · doi:10.1080/10934521003709073
- Valcárcel, 2012, Drugs of abuse in surface and tap waters of the Tagus River basin: heterogeneous photo-Fenton process is effective in their degradation., Environ Int, 41, 35, 10.1016/j.envint.2011.12.006 · doi:10.1016/j.envint.2011.12.006
- Wilbers, 2009, Effects of a drought period on physico-chemical surface water quality in a regional catchment area., J Environ Monit, 11, 1298, 10.1039/b816109g · doi:10.1039/b816109g
Cited by
Urban blue spaces and human health: A systematic review and meta-analysis of quantitative studies
Smith, N., Georgiou, M., King, A. C., Tieges, Z., Webb, S., & Chastin, S. (2021) · Cities · doi:10.1016/j.cities.2021.103413 · Cited by 212
Brown, J., Acey, C. S., Anthonj, C., Barrington, D. J., Beal, C. D., Capone, D., Cumming, O., Pullen Fedinick, K., MacDonald Gibson, J., Hicks, B., et al. (2023) · The Lancet Global Health · doi:10.1016/s2214-109x(23)00006-2 · Cited by 121
Metadata
- Authors
- Villanueva, C. M., Kogevinas, M., Cordier, S., Templeton, M. R., Vermeulen, R., Nuckols, J. R., Nieuwenhuijsen, M. J., & Levallois, P.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-03
- Volume
- 122
- Issue
- 3
- Pages
- 213-221
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W2090038789
- Cited by
- 256
- References
- 81
- FWCI
- 15.56
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Assessing Exposure and Health Consequences of Chemicals in Drinking Water: Current State of Knowledge and Research Needs. https://app.cochat.ai/papers/10.1289/ehp.1206229
- The paper
- Villanueva, C. M., Kogevinas, M., Cordier, S., Templeton, M. R., Vermeulen, R., Nuckols, J. R., Nieuwenhuijsen, M. J., & Levallois, P. (2014). Assessing Exposure and Health Consequences of Chemicals in Drinking Water: Current State of Knowledge and Research Needs. Environmental Health Perspectives. https://doi.org/10.1289/ehp.1206229
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
