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Xenoestrogens released from lacquer coatings in food cans.
Open accessAbstract
We present data showing that some foods preserved in lacquer-coated cans and the liquid in them may acquire estrogenic activity. Hormonal activity was measured using the E-screen bioassay. The biological activity of vegetables packed in cans was a result of plastic monomers used in manufacturing the containers. The plastic monomer bisphenol-A, identified by mass spectrometry, was found as a contaminant not only in the liquid of the preserved vegetables but also in water autoclaved in the cans. The amount of bisphenol-A in the extracts accounted for all the hormonal activity measured. Although the presence of other xenoestrogens cannot be ruled out, it is apparent that all estrogenic activity in these cans was due to bisphenol-A leached from the lacquer coating. The use of plastic in food-packaging materials may require closer scrutiny to determine whether epoxy resins and polycarbonates contribute to human exposure to xenoestrogens.
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Citations
Cited by
Phthalates and other additives in plastics: human exposure and associated health outcomes
Meeker, J. D., Sathyanarayana, S., & Swan, S. H. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0268 · Cited by 835
Alonso-Magdalena, P., Morimoto, S., Ripoll, C., Fuentes, E., & Nadal, A. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8451 · Cited by 632
Bisphenol A interacts with the estrogen receptor α in a distinct manner from estradiol
Gould, J. C., Leonard, L. S., Maness, S. C., Wagner, B. L., Conner, K., Zacharewski, T., Safe, S., McDonnell, D. P., & Gaido, K. W. (1998) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(98)00084-7 · Cited by 510
Acute toxicity, mutagenicity, and estrogenicity of bisphenol‐A and other bisphenols
Chen, M., Ike, M., & Fujita, M. (2002) · Environmental Toxicology · doi:10.1002/tox.10035 · Cited by 508
Perinatal Exposure to Bisphenol A Alters Early Adipogenesis in the Rat
Somm, E., Schwitzgebel, V. M., Toulotte, A., Cederroth, C. R., Combescure, C., Nef, S., Aubert, M. L., & Hüppi, P. S. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.11342 · Cited by 467
Metadata
- Authors
- Brotons, J. A., Olea-Serrano, M. F., Villalobos, M., Pedraza, V, & Olea, N.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 1995-06
- Volume
- 103
- Issue
- 6
- Pages
- 608-612
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W1982477373
- Cited by
- 942
- References
- 0
- FWCI
- 17.97
- Type
- journal article
- Language
- en
- Open access
- gold
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- Brotons, J. A., Olea-Serrano, M. F., Villalobos, M., Pedraza, V, & Olea, N. (1995). Xenoestrogens released from lacquer coatings in food cans. Environmental Health Perspectives. https://doi.org/10.1289/ehp.95103608
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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