The DOI matches its Crossref record; 204 of the 204 references it cites were found in a registry or an index.
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols
Abstract
Recent years have brought growing recognition of the need for clinical criteria for myalgic encephalomyelitis (ME), which is also called chronic fatigue syndrome (CFS). An Expert Subcommittee of Health Canada established the Terms of Reference, and selected an Expert Medical Consensus Panel representing treating physicians, teaching faculty and researchers. A Consensus Workshop was held on March 30 to April 1,2001 to culminate the review process and establish consensus for a clinical working case definition, diagnostic protocols and treatment protocols. We present a systematic clinical working case definition that encourages a diagnosis based on characteristic patterns of symptom clusters, which reflect specific areas of pathogenesis. Diagnostic and treatment protocols, and a short overview of research are given to facilitate a comprehensive and integrated approach to this illness. Throughout this paper, “myalgic encephalomyelitis” and “chronic fatigue syndrome” are used interchangeably and this illness is referred to as “ME/CFS.”
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“ME/CFS was diagnosed according to current research case definitions1,28: fatigue of greater than 6 months duration and at least 4 of 8 symptoms including exercise-induced relapse, myalgia, arthralgia, headache of a new and different type, nonrestorative sleep, cognitive complaints, sore throat, and tender lymph nodes.”
From Leveraging Prior Knowledge of Endocrine Immune Regulation in the Therapeutically-relevant Phenotyping of Women with Chronic Fatigue Syndrome (2019) · cites this paper as [28]
In the citing paper
“The Institute of Medicine [1] has proposed diagnostic criteria which are very similar to the Canadian Consensus Criteria [88].”
From Systematic review of mind‐body interventions to treat myalgic encephalomyelitis/chronic fatigue syndrome (2021) · cites this paper as [88]
Citations
Cites
Items 201–204 of 204
Levine, S. M., Eastman, H., & Ablashi, D. V. (2001) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v09n01_04 · Cited by 4
Neurocognitive Testing in Chronic Fatigue Syndrome
DeLuca, J., & Schmaling, K. B. (1995) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v01n03_04 · Cited by 4
Jl, B., Perret‐Liaudet, A., Later, R., Peyramond, D., & Cozon, G. J. N. (2001) · PubMed · Cited by 4
Blood transfusion and chronic fatigue syndrome
Meirleir, K. D., Becker, P. D., & Campine, I. (1999) · VUBIR (Vrije Universiteit Brussel) · Cited by 4
Flagged first, then by citations
Research works printed but not linked: 24
- Holmes GP, 1987, Is Epstein-Barr virus the cause? JAMA May, 257, 2297
- Martin WJ, 1997, Pathobiol, 65, 15
- Bell DS, 1995, Addison-Wesley Pub-lishing Co, Pg. 45
- Dowsett EG, 1997, J CFS, 3, 29
- Scott LV, 1999, Funct Neurol, 14, 3
- Jason LA, 2001, Med & Psychia, 4, 29
- Wessely S, 1997, The prevalence and mor-bidity of chronic fatigue and chronic fatigue syndrome: a prospective primary care cen-ter. Am J of Pub Health, 87, 1449
- Sue DY, 1999, Chest, 99, 931
- Cooper RK, 1991, Houghton Mifflin Co. Boston, 59
- Romano TJ, 1995, WV Med J, 91, 147
- Cawthorne TE, 1945, Proceed Roy Soc of Med, 31, 270
- Cooksey FS, 1945, Proceed Roy Soc of Med, 31, 273
- Ridsdale L, 2001, Br J Gener Pract, Jan, 51, 19
- Jacobson JI, 2001, Gazzeta Medica Italiana-Archivio Per Le Scienze Mediche, 160, 1
- Cochran JW, 2001, J CFS, 8, 65
- Pall ML, 2001, J CFS, 8, 39
- Strayer DR, 1995, J CFS, 1, 35
- Mena I, 1992, Chronic Fatigue Syndrome and the Brain, Bel Air CA, Apr, 25
- Moldofsky H, 1993, Ciba Foundation Symp, 173, 262
- Streeten DHP, 1998, J CFS, 4, 3
- Simpson LO, 1989, N Z Med J, 102, 126
- Brunet IL, 2001, Delayed-type hyper-sensitivity and chronic fatigue syndrome; the usefulness assessing T-cell activation by flow cytometry. Allerg Immunol (Paris), 33, 166
- Nicolson GL, 1999, Med Sentinel, 4, 172
- Nicolson GL, 1998, Biomed Ther, 16, 266
Cited by
Sorted by citations
Myalgic encephalomyelitis: International Consensus Criteria
Carruthers, B. M., van de Sande, M. I., Meirleir, K. L. D., Klimas, N. G., Broderick, G., Mitchell, T., Staines, D., Powles, A. C. P., Speight, N., Vallings, R., et al. (2011) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2011.02428.x · Cited by 1,234
Self-citationPrins, J. B., van der Meer, J. W., & Bleijenberg, G. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68073-2 · Cited by 974
Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus
Raman, B., Bluemke, D. A., Lüscher, T. F., & Neubauer, S. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac031 · Cited by 717
Unexplained post-acute infection syndromes
Choutka, J., Jansari, V., Hornig, M., & Iwasaki, A. (2022) · Nature Medicine · doi:10.1038/s41591-022-01810-6 · Cited by 604
Rao, A. V., Bested, A. C., Beaulne, T. M., Katzman, M. A., Iorio, C., Berardi, J. M., & Logan, A. C. (2009) · Gut Pathogens · doi:10.1186/1757-4749-1-6 · Cited by 577
Self-citation
Metadata
- Authors
- Carruthers, B. M., Jain, A. K., De Meirleir, K. L., Peterson, D. L., Klimas, N. G., Lerner, A. M., Bested, A. C., Flor-Henry, P., Joshi, P., Powles, A. C. P., Sherkey, J. A., & van de Sande, M. I.
- Affiliations
- Ottawa Hospital (CA)
- University of Miami (US)
- Wayne State University (US)
- Sunnybrook Health Science Centre (CA)
- University of Alberta (CA)
- Memorial University of Newfoundland (CA)
- McMaster University (CA)
- University Health Network (CA)
- Corresponding author
- Carruthers, Bruce M.
- Venue
- Journal of Chronic Fatigue Syndrome
- Publisher
- Informa UK Limited
- Published
- 2003-01
- Volume
- 11
- Issue
- 1
- Pages
- 7-115
- ISSN
- 1057-3321 (ISSN-L)
- 1547-0660
- OpenAlex
- W2008087869
- Cited by
- 1,180
- References
- 203
- Citations by year
- 2026: 69 · 2025: 109 · 2024: 105 · 2023: 104 · 2022: 88 · 2021: 94 · 2020: 81 · 2019: 69 · 2018: 52 · 2017: 57 · 2016: 46 · 2015: 70 · 2014: 36 · 2013: 37 · 2012: 23
- FWCI
- 6.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Chronic Fatigue Syndrome (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Keywords
- chronic fatigue syndrome, clinical case definition, diagnostic criteria, symptom clusters, pathogenesis, treatment protocols, consensus panel, Health Canada
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
