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Cited by 268

The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.

Role of preoperative carbohydrate loading: a systematic review

Open access
Bilku, DK, Dennison, AR, Hall, TC, Metcalfe, MS, Garcea, G·2014·The Annals of The Royal College of Surgeons of England

Abstract

INTRODUCTION: Surgical stress in the presence of fasting worsens the catabolic state, causes insulin resistance and may delay recovery. Carbohydrate rich drinks given preoperatively may ameliorate these deleterious effects. A systematic review was undertaken to analyse the effect of preoperative carbohydrate loading on insulin resistance, gastric emptying, gastric acidity, patient wellbeing, immunity and nutrition following surgery. METHODS: All studies identified through PubMed until September 2011 were included. References were cross-checked to ensure capture of cited pertinent articles. RESULTS: Overall, 17 randomised controlled trials with a total of 1,445 patients who met the inclusion criteria were identified. Preoperative carbohydrate drinks significantly improved insulin resistance and indices of patient comfort following surgery, especially hunger, thirst, malaise, anxiety and nausea. No definite conclusions could be made regarding preservation of muscle mass. Following ingestion of carbohydrate drinks, no adverse events such as apparent or proven aspiration during or after surgery were reported. CONCLUSIONS: Administration of oral carbohydrate drinks before surgery is probably safe and may have a positive influence on a wide range of perioperative markers of clinical outcome. Further studies are required to determine its cost effectiveness.

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Metadata

Authors
Bilku, D., Dennison, A., Hall, T., Metcalfe, M., & Garcea, G.
Venue
The Annals of The Royal College of Surgeons of England
Published
2014-01
Volume
96
Issue
1
Pages
15-22
ISSN
  • 0035-8843 (ISSN-L)
  • 1478-7083
OpenAlex
W1971344036
Cited by
268
References
34
FWCI
2.42
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Role of preoperative carbohydrate loading: a systematic review. https://app.cochat.ai/papers/10.1308/003588414x13824511650614
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Bilku, D., Dennison, A., Hall, T., Metcalfe, M., & Garcea, G. (2014). Role of preoperative carbohydrate loading: a systematic review. The Annals of The Royal College of Surgeons of England. https://doi.org/10.1308/003588414x13824511650614

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.