Physical organic methods in carotenoid research
Open accessAbstract
The ever increasing importance of physical methods in the elucidation of the structure and configuration of carotenoids is reviewed.The use of solvent partition, chromatography, X-ray crystallography, infra-red spectroscopy and optical rotary dispersion are briefly discussed.Special emphasis is given to the application of absorption spectroscopy and to 220 MHz proton magnetic resonance spectroscopy of carotenoids.Mass spectroscopic studies of the characteristic fragmentation of the carotenes, and a possible mechanism for the fragmentation of the polyene chain, are discussed in detail. * * *). max.nm ( petrote um ether) ~apocarotenals 15,15~dehydrop -apocarolenal s
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The Carr-Price reaction using antimony trichloride was a primary means of retinol detection before chromatography.
“This color change, when initiated using antimony trichloride as the Lewis acid, is known as the Carr–Price reaction and was a primary means of retinol detection and quantification prior to the advent of chromatographic methods.167”
From Chemistry of the Retinoid (Visual) Cycle (2014) · cites this paper as [167]
The opening passage (indexed as Abstract; page unavailable) says the Carr–Price reaction, including its antimony trichloride form, was a main tool for routine analysis and remained an analytical method for vitamin A. It does not establish retinol quantification, and its example is analysis of chromatographic fractions—not use before chromatography existed. (LLM, conf=0.87)
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Chemistry and biochemistry of plant pigments
Goodwin, T. W. (1976) · Medical Entomology and Zoology · Cited by 3,081 · see citing works
ADVANCES IN ORGANIC CHEMISTRY: METHODS AND RESULTS
(1966) · Elsevier eBooks · doi:10.1016/b978-0-08-012210-6.50018-1 · Cited by 132 · see citing works
ADVANCES IN ORGANIC CHEMISTRY METHODS AND RESULTS
(1962) · Elsevier eBooks · doi:10.1016/b978-0-08-009654-4.50013-3 · Cited by 29 · see citing works
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Research works printed but not linked: 33
- P. E. Blatz and D. L. Pippert. J .Am. Chem. Soc. 90, 1296 (1968).
- A. Wasserman . .Nfol. Phys. 2, 226 (1959).
- a T. S. Sorensen. J. Am. Chem. Soc. 87, 5075 (1965).
- J. H. C. Smith. J. Am. Chem. Soc. 58, 247 (1936).
- L. Zechmeister and A. Polgar. J. Am. Chem. Soc. 65, 1522 (1943).
- K. Hirayama. J. Am. Chem. Soc. 77, 373 (1955).
- J. Dale. Acta Chem. Scand. 8, 1235 (1954); 11, 265 (1957).
- B. C. L. Weedon. Chem. in Britain 3, 424 (1967).
- S. L. Jensen. Pure Appl. Chem. 14, 227 (1966).
- K. Lunde and L. Zechmeister. J. Am. Chem. Soc. 77, 1647 (1955).
- E. Nocoad, V. Tamas, G. Neamtu and C. Bodea. Liebigs Ann. 697, 201 (1966).
- H. Mayer. [F. Hoffm~nn-La Rache, Basle (Switzerland)], unpublished results. 14a trans-ß-Ionylidenecrotonic acid E. L. Eichhorn and C. H. MacGillavry. Acta Cryst. 12, 872 (1959).
- b cis-ß-I onylidenecrotonic acid B. Koch and C. H. MacGillavry. Acta Cryst. 16, A48 (1963). 14c Vitamin A acid (all-trans, triclinic modification) C. H. Stam and C. H. MacGillavry. Acta Cryst. 16, 62 (1963). 14d 7 ,7' -Dihydro-ß-carotene C. Sterling. Acta Cryst. 17, 500 (1964).
- 14e ß-Carotene C. Sterling. Acta Cryst. 17, 1224 (1964). 14! 15,15'-Dehydro-ß-carotene W. G. Sly. Acta Cry~t. 17, 501 (1964).
- Canthaxanthin J. C. ]. Bart and C. H. MacGillavry. Acta Cryst. 24, 1587 (1968). 14h 15, 15' -Dehydrocanthaxanthin ].
- C. J. Bart and C. H. MacGillavry. Acta Cryst. 24, 1569 (1968).
- C. A. Coulson. J. Chem. PhyJ. 7, 1069 (1939).
- L. Pauling. Fortschr. Chem. Org. Naturstoffe 3, 203 (1939).
- M. Buchwald and W. P. Jencks. Biochemistry 1, 834 (1968).
- S. L. Jensen and A. Jensen. Progr. Chem. Fats and Lipids, (Ed. R. T. Holman), Vol. VIII, part 2, p. 129, Pergarnon Press, Oxford (1965).
- U. Schwieter, H. R. Bolliger, L. H. Chopard-dit-Jean, G. Englert, M. Kofler, A. König, C. v. Planta, R. Ruegg, W. Vetter and 0. Isler. Chimia (Switz.) 19, 294 (1965).
- D. J. Patel, Nature 221, 825 (1969).
- S. L. Jensen, S. Hertzberg, 0. B. Weeks and U. Schwieter. Acta Chem. Scand. 22, 1171 (1968).
- U. Schwieter and S. L.Jensen. Acta Chem. Scand., 23, 1057 (1969)
- R. Kuhn and A. Winterstein. Chem. Ber. 65, 1873 (1932).
- K. Biemann. Mass Spectrometry. McGraw Hili, New York, p. 103 (1962).
- U. Schwieter, H. Gutmann, H. Lindlar, R. Marbet, N. Rigassi, R. Rüegg, S. F. Schaeren and 0. Isler. Helv. Chim. Acta 49, 369 (1966).
- C. R. Enzell, G. W. Francis and S. L. Jensen. Acta Chem. Scand. 22, 1054 (1968).
- C. R. Enzell, G. W. Fraucis and S. L. Jensen. Acta Chem. Scand., 23, 727 (1969).
- R. Kuhn and A. Winterstein. Chem. Ber. 66, 429, 1733 (1933).
- G. G. McKeown, Journal ofthe A.O.A.C. 48, 835 (1965).
- M. Barher and R. M. Elliott. Proceedings ofthe 12th. ASTM Conference, Montreal, (1964).
- W. C. Day andj. G. Erdman. Science 141, 808 (1963).
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Chemistry of the Retinoid (Visual) Cycle
Kiser, P. D., Golczak, M., & Palczewski, K. (2014) · Chemical Reviews · doi:10.1021/cr400107q · Cited by 353 · see citing works
- Authors
- Schwieter, U., Englert, G., Rigassi, N., & Vetter, W.
- Affiliations
- F. Hoffmann-La Roche AG (CH)
- Venue
- Pure and Applied Chemistry
- Publisher
- Walter de Gruyter GmbH
- Published
- 1969-01-01
- Volume
- 20
- Issue
- 4
- Pages
- 365-420
- ISSN
- 0033-4545 (ISSN-L)
- 1365-3075
- OpenAlex
- W1969658875
- Cited by
- 87
- References
- 3
- Citations by year
- 2024: 1 · 2023: 1 · 2017: 1 · 2015: 1 · 2014: 1 · 2013: 3
- FWCI
- 2.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Pure and Applied Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Spectroscopy › Molecular spectroscopy and chirality
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Spectroscopy and Quantum Chemical Studies
- Keywords
- carotenoids, spectroscopy, photochemistry, structure-activity relationship
- MeSH terms
- Carotenoids, Chemistry, Physical, Chromatography, Crystallography, Methods, Research, Solvents, Spectrum Analysis, Chemical Phenomena
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