Studies on the red sweat of the Hippopotamus amphibius
Abstract
The secretion from the hippopotamus' skin changes its color from colorless to red, and then brown by polymerization of its pigments. The responsible pigments for the coloring reaction were isolated and denoted as hipposudoric acid (the red pigment) and norhipposudoric acid (the orange pigment). The syntheses of these pigments and the related derivatives were performed, and the latter were of use to elucidate the structures of these pigments including their tautomeric structures in aprotic and protic solvents. These pigments were estimated to be medicines for the hippopotamus, having the effect of both protecting the skin from sunburn and preventing infection by some microbes.
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Subdermal glands of C. liberiensis secrete an oily clear-to-white, foamy fluid that protects the skin against sunburn, dehydration, and bacterial infection.
“Subdermal glands secrete an oily clear-to-white, foamy fluid that protects the skin against sunburn, dehydration, and bacterial infection (Eulenberger 1995;Hashimoto et al. 2007).”
From Choeropsis liberiensis (Artiodactyla: Hippopotamidae) (2019) · cites this paper as Hashimoto et al. 2007
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Flacke, G. L., Chambers, B. K., Martin, G. B., & Paris, M. C. J. (2015) · Der Zoologische Garten · doi:10.1016/j.zoolgart.2015.07.006 · Cited by 13 · see citing works
Choeropsis liberiensis (Artiodactyla: Hippopotamidae)
Flacke, G. L., & Decher, J. (2019) · Mammalian Species · doi:10.1093/mspecies/sez017 · Cited by 9 · see citing works
- Authors
- Hashimoto, K., Saikawa, Y., & Nakata, M.
- Affiliations
- Kyoto Pharmaceutical University (JP)
- Keio University (JP)
- Venue
- Pure and Applied Chemistry
- Publisher
- Walter de Gruyter GmbH
- Published
- 2007-01-01
- Volume
- 79
- Issue
- 4
- Pages
- 507-517
- ISSN
- 0033-4545 (ISSN-L)
- 1365-3075
- OpenAlex
- W2105202236
- Cited by
- 26
- References
- 0
- Citations by year
- 2026: 1 · 2023: 1 · 2022: 2 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2015: 5 · 2014: 1 · 2013: 4 · 2012: 3
- FWCI
- 0.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pure and Applied Chemistry (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Metabolism and Applications
- Health Sciences › Medicine › Pharmacology › Biological Stains and Phytochemicals
- Keywords
- hippopotamus, skin pigments, pigment synthesis, tautomerism, solvent effects, antimicrobial activity
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