Cited by 536Bone health and osteoporosis researchNutrition and Health in AgingNutritional Studies and Diet

The DOI matches its Crossref record; 58 of the 59 references it cites were found in a registry or an index.

Effect of Dietary Protein on Bone Loss in Elderly Men and Women: The Framingham Osteoporosis Study

Hannan, Marian T., Tucker, Katherine L., Dawson-Hughes, Bess, Cupples, L. Adrienne, Felson, David T., Kiel, Douglas P.·2000·Journal of Bone and Mineral Research

DOI 10.1359/jbmr.2000.15.12.2504

Open this paper in CoChat — free account

Abstract

Few studies have evaluated protein intake and bone loss in elders. Excess protein may be associated with negative calcium balance, whereas low protein intake has been associated with fracture. We examined the relation between baseline dietary protein and subsequent 4-year change in bone mineral density (BMD) for 391 women and 224 men from the population-based Framingham Osteoporosis Study. BMD (g/cm2) was assessed in 1988-1989 and in 1992-1993 at the femur, spine, and radius. Usual dietary protein intake was determined using a semiquantitative food frequency questionnaire (FFQ) and expressed as percent of energy from protein intake. BMD loss over 4 years was regressed on percent protein intake, simultaneously adjusting for other baseline factors: age, weight, height, weight change, total energy intake, smoking, alcohol intake, caffeine, physical activity, calcium intake, and, for women, current estrogen use. Effects of animal protein on bone loss also were examined. Mean age at baseline (±SD) of 615 participants was 75 years (±4.4; range, 68-91 years). Mean protein intake was 68 g/day (±24.0; range, 14-175 g/day), and mean percent of energy from protein was 16% (±3.4; range, 7-30%). Proportional protein intakes were similar for men and women. Lower protein intake was significantly related to bone loss at femoral and spine sites (p ≤ 0.04) with effects similar to 10 lb of weight. Persons in the lowest quartile of protein intake showed the greatest bone loss. Similar to the overall protein effect, lower percent animal protein also was significantly related to bone loss at femoral and spine BMD sites (all p < 0.01) but not the radial shaft (p = 0.23). Even after controlling for known confounders including weight loss, women and men with relatively lower protein intake had increased bone loss, suggesting that protein intake is important in maintaining bone or minimizing bone loss in elderly persons. Further, higher intake of animal protein does not appear to affect the skeleton adversely in this elderly population.

Integrity signals

Registry

Crossref · 10.1359/jbmr.2000.15.12.2504

Cites

58 of 58 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Reproducibility and validity of a semiquantitative food frequency questionnaire
WILLETT, W. C., SAMPSON, L., STAMPFER, M. J., ROSNER, B., BAIN, C., WITSCHI, J., HENNEKENS, C. H., & SPEIZER, F. E. (1985) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114086 · Cited by 4,274
Risk Factors for Hip Fracture in White Women
Cummings, S. R., Nevitt, M. C., Browner, W. S., Stone, K., Fox, K. M., Ensrud, K. E., Cauley, J., Black, D., & Vogt, T. M. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503233321202 · Cited by 3,595
Total energy intake: implications for epidemiologic analyses.
WILLETT, W., & STAMPFER, M. J. (1986) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114366 · Cited by 2,751
RE: “TOTAL ENERGY INTAKE: IMPLICATIONS FOR EPIDEMIOLOGIC ANALYSES”
Palmgren, J., & Kushi, L. H. (1991) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115841 · Cited by 2,712
Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: Synopsis of a WHO report
Kanis, J. А., & Kanis, J. А. (1994) · Osteoporosis International · doi:10.1007/bf01622200 · Cited by 2,532
Epidemiological approaches to heart disease: the Framingham study
Dawber, T. R., Meadors, G. F., & Moore, F. E. (1951) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.41.3.279 · Cited by 2,148
Reproducibility and Validity of an Expanded Self-Administered Semiquantitative Food Frequency Questionnaire among Male Health Professionals
Rimm, E. B., Giovannucci, E. L., Stampfer, M. J., Colditz, G. A., Litin, L. B., & Willett, W. C. (1992) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116211 · Cited by 2,104
The Framingham Study
Dawber, T. R. (1980) · Harvard University Press eBooks · doi:10.4159/harvard.9780674492097 · Cited by 1,965
Dietary supplementation in elderly patients with fractured neck of the femur
Delmi, M., Rapin, C. H., Bengoa, J., Bonjour, J.-P., Vasey, H., & Delmas, P. D. (1990) · The Lancet · doi:10.1016/0140-6736(90)91073-j · Cited by 825
Some health benefits of physical activity. The Framingham Study
Kannel, W. B. (1979) · Archives of Internal Medicine · doi:10.1001/archinte.139.8.857 · Cited by 783

Show all 59 references

Research works printed but not linked: 2

Willett, 1990, Nutritional Epidemiology Monographs in Epidemiology & Biostatistics
McDowell, 1994, Advance data from Vital and Health Statistics 255

Sorted by citations

Items 101–200 of 536

Dairy in Adulthood: From Foods to Nutrient Interactions on Bone and Skeletal Muscle Health
Bonjour, J., Kraenzlin, M., Levasseur, R., Warren, M. P., & Whiting, S. J. (2013) · Journal of the American College of Nutrition · doi:10.1080/07315724.2013.816604 · Cited by 99
Building healthy bones throughout life: an evidence‐informed strategy to prevent osteoporosis in Australia
Ebeling, P. R., Daly, R. M., Kerr, D. A., & Kimlin, M. G. (2013) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2013.tb04225.x · Cited by 89
Nutrition and Bone Health in Women after the Menopause
Rizzoli, R., Bischoff-Ferrari, H. A., Dawson‐Hughes, B., & Weaver, C. M. (2014) · Women s Health · doi:10.2217/whe.14.40 · Cited by 84
Self-citation
Dietary Protein Requirement of Men >65 Years Old Determined by the Indicator Amino Acid Oxidation Technique Is Higher than the Current Estimated Average Requirement
Rafii, M., Chapman, K., Elango, R., Campbell, W. W., Ball, R. O., Pencharz, P. B., & Courtney-Martin, G. (2016) · The Journal of Nutrition · doi:10.3945/jn.115.225631 · Cited by 87
Body Fat Percentage, Body Mass Index, Fat Mass Index and the Ageing Bone: Their Singular and Combined Roles Linked to Physical Activity and Diet
Tomlinson, D. J., Erskine, R. M., Morse, C. I., & Onambélé-Pearson, G. L. (2019) · Nutrients · doi:10.3390/nu11010195 · Cited by 84
Dietary protein and skeletal health: a review of recent human research
Kerstetter, J. E., Kenny, A. M., & Insogna, K. L. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3283419441 · Cited by 84
The Effect of a Whey Protein Supplement on Bone Mass in Older Caucasian Adults
Kerstetter, J. E., Bihuniak, J. D., Brindisi, J., Sullivan, R., Mangano, K. M., Larocque, S., Kotler, B. M., Simpson, C. A., Cusano, A. M., Gaffney‐Stomberg, E., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-3792 · Cited by 84
Does dietary protein reduce hip fracture risk in elders? The Framingham osteoporosis study
Misra, D., Berry, S. D., Broe, K. E., McLean, R. R., Cupples, L. A., Tucker, K. L., Kiel, D. P., & Hannan, M. T. (2010) · Osteoporosis International · doi:10.1007/s00198-010-1179-4 · Cited by 83
Self-citation
Interactions of Interleukin-6 Promoter Polymorphisms With Dietary and Lifestyle Factors and Their Association With Bone Mass in Men and Women From the Framingham Osteoporosis Study
Ferrari, S., Karasik, D., Liu, J., Karamohamed, S., Herbert, A. G., Cupples, L. A., & Kiel, D. P. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.040103 · Cited by 83
Self-citation
Evidence-based guidelines for the treatment of postmenopausal osteoporosis: a consensus document of the Belgian Bone Club
Boonen, S., Body, J., Boutsen, Y., Devogelaer, J., Goemaere, S., Kaufman, J., Rozenberg, S., & Reginster, J. (2005) · Osteoporosis International · doi:10.1007/s00198-004-1812-1 · Cited by 83
Dietary protein and bone health
Ginty, F. (2003) · Proceedings of The Nutrition Society · doi:10.1079/pns2003307 · Cited by 83
Bone disease in idiopathic hypercalciuria
Heilberg, I. P., & Weisinger, J. R. (2006) · Current Opinion in Nephrology & Hypertension · doi:10.1097/01.mnh.0000232880.58340.0c · Cited by 82
The Mediterranean diet and menopausal health: An EMAS position statement
Cano, A., Marshall, S., Zolfaroli, I., Bitzer, J., Ceauşu, I., Chedraui, P. A., Durmuşoğlu, F., Erkkola, R. U., Goulis, D. G., Hirschberg, A. L., et al. (2020) · Maturitas · doi:10.1016/j.maturitas.2020.07.001 · Cited by 91
Protective role of n-3 lipids and soy protein in osteoporosis
Fernandes, G., Lawrence, R. A., & Sun, D. (2003) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/s0952-3278(03)00060-7 · Cited by 81
Amino acid supplementation alters bone metabolism during simulated weightlessness
Zwart, S. R., Davis-Street, J. E., Paddon-Jones, D., Ferrando, A. A., Wolfe, R. R., & Smith, S. M. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01406.2004 · Cited by 80
Effects of meat consumption and vegetarian diet on risk of wrist fracture over 25 years in a cohort of peri- and postmenopausal women
Thorpe, D. L., Knutsen, S. F., Beeson, W. L., Rajaram, S., & Fraser, G. E. (2007) · Public Health Nutrition · doi:10.1017/s1368980007000808 · Cited by 80
Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years
Darling, A. L., MANDERS, R. J. F., Sahni, S., Zhu, K., Hewitt, C. E., Prince, R. L., Millward, D. J., & Lanham-New, S. A. (2019) · Osteoporosis International · doi:10.1007/s00198-019-04933-8 · Cited by 80
Consumption of Yogurts Fortified in Vitamin D and Calcium Reduces Serum Parathyroid Hormone and Markers of Bone Resorption: A Double-Blind Randomized Controlled Trial in Institutionalized Elderly Women
Bonjour, J., Benoit, V., Payen, F., & KRAENZLIN, M. E. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1274 · Cited by 79
Calcium intake and disease prevention
Heaney, R. P. (2006) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302006000400014 · Cited by 79
An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly
McCarty, M. F., & DiNicolantonio, J. J. (2015) · AGE · doi:10.1007/s11357-015-9823-8 · Cited by 79
Dietary protein intake and subsequent falls in older men and women: The Framingham study
Zoltick, E. S., Sahni, S., McLean, R. R., Quach, L., Casey, V. A., & Hannan, M. T. (2011) · The journal of nutrition health & aging · doi:10.1007/s12603-011-0028-2 · Cited by 78
Self-citation
The dietary protein, IGF-I, skeletal health axis
Bonjour, J. (2016) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2016-0003 · Cited by 82
Phosphate decreases urine calcium and increases calcium balance: A meta-analysis of the osteoporosis acid-ash diet hypothesis
Fenton, T. R., Lyon, A. W., Eliasziw, M., Tough, S., & Hanley, D. A. (2009) · Nutrition Journal · doi:10.1186/1475-2891-8-41 · Cited by 77
Protein intake and bone disorders in the elderly
Rizzoli, R., Ammann, P., Chevalley, T., & Bonjour, J.-P. (2001) · Joint Bone Spine · doi:10.1016/s1297-319x(01)00295-0 · Cited by 77
UK Food Standards Agency α-linolenic acid workshop report
Sanderson, P., Finnegan, Y. E., Williams, C. M., Calder, P. C., Burdge, G. C., Wootton, S. A., Griffin, B. A., Millward, D. J., Pegge, N. C., & Bemelmans, W. J. E. (2002) · British Journal Of Nutrition · doi:10.1079/bjn2002691 · Cited by 76
Protective Association of Milk Intake on the Risk of Hip Fracture: Results from the Framingham Original Cohort
Sahni, S., Mangano, K. M., Tucker, K. L., Kiel, D. P., Casey, V. A., & Hannan, M. T. (2014) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2219 · Cited by 74
Self-citation
Nutritional aspects of the prevention and treatment of osteoporosis
Peters, B. S. E., & Martini, L. A. (2010) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302010000200014 · Cited by 74
Controlled Substitution of Soy Protein for Meat Protein: Effects on Calcium Retention, Bone, and Cardiovascular Health Indices in Postmenopausal Women
Roughead, Z. K., Hunt, J. R., Johnson, L. K., Badger, T. M., & LYKKEN, G. I. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0393 · Cited by 73
The ratio of animal protein intake to potassium intake is a predictor of bone resorption in space flight analogues and in ambulatory subjects
Zwart, S. R., Hargens, A. R., & Smith, S. M. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.4.1058 · Cited by 73
A threshold for low-protein-diet–induced elevations in parathyroid hormone
Kerstetter, J. E., Svastisalee, C., Caseria, D. M., Mitnick, M., & Insogna, K. L. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.1.168 · Cited by 73
Protein intake and bone health: the influence of belief systems on the conduct of nutritional science
Heaney, R. P. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.1.5 · Cited by 73
The interaction between dietary protein and bone health
Jesudason, D. R., & Clifton, P. M. (2010) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-010-0225-9 · Cited by 71
Protein and calcium: antagonists or synergists?
Heaney, R. P. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/75.4.609 · Cited by 71
Hidden Hunger: Solutions for America’s Aging Populations
Eggersdorfer, M. L., Akobundu, U. O., Bailey, R. L., Shlisky, J., Beaudreault, A. R., Bergeron, G., Blancato, R. B., Blumberg, J. B., Bourassa, M. W., Gomes, F., et al. (2018) · Nutrients · doi:10.3390/nu10091210 · Cited by 77
Self-citation
Associations of protein intake and protein source with bone mineral density and fracture risk: A population-based cohort study
Langsetmo, L., Barr, S. I., Berger, C., Kreiger, N., Rahme, E., Adachi, J. D., Παπαϊωάννου, Α., Kaiser, S., Prior, J. C., Hanley, D. A., et al. (2015) · The journal of nutrition health & aging · doi:10.1007/s12603-015-0544-6 · Cited by 68
Advances in the management of osteoporosis
Hoong, C. W. S., Saul, D., Khosla, S., & Sfeir, J. G. (2025) · BMJ · doi:10.1136/bmj-2024-081250 · Cited by 77
Mediterranean diet as medical prescription in menopausal women with obesity: a practical guide for nutritionists
Barrea, L., Pugliese, G., Laudisio, D., Colao, A., Savastano, S., & Muscogiuri, G. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1755220 · Cited by 66
Acid diet (high-meat protein) effects on calcium metabolism and bone health
Cao, J., & Nielsen, F. H. (2010) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e32833df691 · Cited by 66
Biomarker-calibrated protein intake and bone health in the Women’s Health Initiative clinical trials and observational study
Beasley, J. M., LaCroix, A. Z., Larson, J. C., Huang, Y., Neuhouser, M. L., Tinker, L. F., Jackson, R. D., Snetselaar, L. G., Johnson, K., Eaton, C. B., et al. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.076786 · Cited by 65
Hypercalciuria Associated with High Dietary Protein Intake Is Not Due to Acid Load
Maalouf, N. M., Moe, O. W., ADAMS-HUET, B. A., & Sakhaee, K. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1531 · Cited by 65
Food and Western Disease Health and Nutrition from an Evolutionary Perspective
Lindeberg, S. (2009) · Cited by 64
Epidemiology of osteoporosis
Samelson, E. J., & Hannan, M. T. (2006) · Current Rheumatology Reports · doi:10.1007/s11926-006-0030-6 · Cited by 64
Self-citation
Nutritional disturbance in acid–base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney
Bonjour, J. (2013) · British Journal Of Nutrition · doi:10.1017/s0007114513000962 · Cited by 64
Dietary protein is beneficial to bone health under conditions of adequate calcium intake
Mangano, K. M., Sahni, S., & Kerstetter, J. E. (2013) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000013 · Cited by 63
PPARG by Dietary Fat Interaction Influences Bone Mass in Mice and Humans
Ackert‐Bicknell, C. L., Demissie, S., de Evsikova, C. M., Hsu, Y., DeMambro, V., Karasik, D., Cupples, L. A., Ordovás, J. M., Tucker, K. L., Cho, K., et al. (2008) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.080419 · Cited by 63
Self-citation
The Relation between Dietary Protein, Calcium and Bone Health in Women: Results from the EPIC-Potsdam Cohort
Weikert, C., Walter, D., Hoffmann, K., Kroke, A., Bergmann, M. M., & Boeing, H. (2005) · Annals of Nutrition and Metabolism · doi:10.1159/000087335 · Cited by 62
The effects of dietary protein and amino acids on skeletal metabolism
Bihuniak, J. D., & Insogna, K. L. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.03.024 · Cited by 62
Veganism, bone mineral density, and body composition: a study in Buddhist nuns
Ho-Pham, L., Nguyen, P., Le, T. H. T., Doan, T. A. T., Tran, N. T., Le, T., & Nguyen, T. (2009) · Osteoporosis International · doi:10.1007/s00198-009-0916-z · Cited by 70
The Effects of Dietary Protein on Bone Mineral Mass in Young Adults May Be Modulated by Adolescent Calcium Intake ,
Vatanparast, H., Bailey, D. A., Baxter-Jones, A. D. G., & Whiting, S. J. (2007) · Journal of Nutrition · doi:10.1093/jn/137.12.2674 · Cited by 61
Therapeutic approaches to osteosarcopenia: insights for the clinician
Fatima, M., Brennan-Olsen, S. L., & Duque, G. (2019) · Therapeutic Advances in Musculoskeletal Disease · doi:10.1177/1759720x19867009 · Cited by 84
Protein Intake and Bone Health
Bonjour, J., Chevalley, T., Amman, P., & Rizzoli, R. (2014) · Springer eBooks · doi:10.1007/978-1-4939-2001-3_20 · Cited by 63
Dietary protein and bone health: harmonizing conflicting theories
Thorpe, M. P., & Evans, E. M. (2011) · Nutrition Reviews · doi:10.1111/j.1753-4887.2011.00379.x · Cited by 60
Biological and Clinical Potential of a Palaeolithic Diet*
Lindeberg, S., Cordain, L., & Eaton, S. B. (2003) · Journal of Nutritional & Environmental Medicine · doi:10.1080/13590840310001619397 · Cited by 62
Effects of dietary improvement on bone metabolism in elderly underweight women with osteoporosis: a randomised controlled trial
Hampson, G., Martin, F. C., Moffat, K., Vaja, S., Sankaralingam, S., Cheung, J., Blake, G. M., & Fogelman, I. (2003) · Osteoporosis International · doi:10.1007/s00198-003-1440-1 · Cited by 60
Nutrition and Risk for Osteoporosis
Heaney, R. P. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-415853-5.00028-5 · Cited by 63
Risk factors for developing mineral bone disease in phenylketonuric patients
Mirás, A., Boveda, M. D., Leis, R., Mera, A., Aldamiz-Echevarria, L. J., Lorenzo, J. R. F., Fraga, J. M., & Couce, M. L. (2013) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2012.12.008 · Cited by 59
Effects of Average Childhood Dairy Intake on Adolescent Bone Health
Moore, L. L., Bradlee, M. L., Gao, D., & Singer, M. R. (2008) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2008.05.016 · Cited by 58
Do vegetarians have a normal bone mass?
New, S. A. (2004) · Osteoporosis International · doi:10.1007/s00198-004-1647-9 · Cited by 58
Vitamin and mineral status in patients with hyperphenylalaninemia
Martínez, V. C., Aldamiz-Echevarria, L. J., Dalmau, J., Vitoria, I., Andrade, F., Roca, I., Leis, R., Marmiesse, A. F., & Couce, M. L. (2015) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2015.06.010 · Cited by 57
Inhibition of bone turnover by milk intake in postmenopausal women
Bonjour, J., Brandolini-Bunlon, M., Boirie‌, Y., Morel-Laporte, F., Braesco, V., Bertiére, M.-C., & Souberbielle, J. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114508937429 · Cited by 57
Diet and hip fractures among elderly Europeans in the EPIC cohort
Benetou, V., Orfanos, P., Zylis, D., Sieri, S., Contiero, P., Tumino, R., Giurdanella, M. C., Peeters, P. H. M., Linseisen, J., Nieters, A., et al. (2010) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2010.226 · Cited by 55
The Relationship between Dietary Protein Consumption and Risk of Fracture: a subgroup and dose-response meta-analysis of prospective cohort studies
Wu, A., Sun, X., Lv, Q., Zhou, Y., Xia, D., Xu, H., Huang, Q.-S., & Chi, Y.-L. (2015) · Scientific Reports · doi:10.1038/srep09151 · Cited by 56
Body mass index and bone loss among postmenopausal women: the 10-year follow-up of the OSTPRE cohort
Saarelainen, J., Kiviniemi, V. V., Kröger, H., Tuppurainen, M. T., NISKANEN, L. K., Jurvelin, J. S., & Honkanen, R. (2011) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-011-0305-5 · Cited by 55
Effects of high-whey-protein intake and resistance training on renal, bone and metabolic parameters in rats
Aparicio, V. A., Nebot, E., Porres, J. M., Ortega, F. B., Heredia‐Jimenez, J., López-Jurado, M., & Ramírez, P. A. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510004393 · Cited by 56
Calcium and protein in bone health
Dawson‐Hughes, B. (2003) · Proceedings of The Nutrition Society · doi:10.1079/pns2003267 · Cited by 53
Self-citation
Dairy Foods: Current Evidence of their Effects on Bone, Cardiometabolic, Cognitive, and Digestive Health
Hess, J., Jonnalagadda, S. S., & Slavin, J. L. (2015) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12183 · Cited by 52
Protein Intake, Weight Loss, and Bone Mineral Density in Postmenopausal Women
Campbell, W. W., & Tang, M. (2010) · The Journals of Gerontology Series A · doi:10.1093/gerona/glq083 · Cited by 52
Protein-enriched meal replacements do not adversely affect liver, kidney or bone density: an outpatient randomized controlled trial
Li, Z., Treyzon, L., Chen, S., Yan, E. W. C., Thames, G., & Carpenter, C. L. (2010) · Nutrition Journal · doi:10.1186/1475-2891-9-72 · Cited by 52
Dietary interventions for better management of osteoporosis: An overview
Guo, D., Zhao, M., Xu, W., He, H., Li, B., & Hou, T. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1944975 · Cited by 54
A Positive Association of Lumbar Spine Bone Mineral Density with Dietary Protein Is Suppressed by a Negative Association with Protein Sulfur
Thorpe, M. P., Mojtahedi, M. C., Chapman‐Novakofski, K., McAuley, E., & Evans, E. M. (2008) · Journal of Nutrition · doi:10.1093/jn/138.1.80 · Cited by 51
A fruit, milk and whole grain dietary pattern is positively associated with bone mineral density in Korean healthy adults
Shin, S., Sung, J., & Joung, H. (2014) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2014.231 · Cited by 50
Nutritional Determinants of Bone Health
Morgan, K. T. (2008) · Journal of Nutrition for the Elderly · doi:10.1080/01639360802059670 · Cited by 49
Dietary Habits, Nutrients and Bone Mass in Spanish Premenopausal Women: The Contribution of Fish to Better Bone Health
García, J. F. C., Morán, J. M., Roncero‐Martín, R., Rey‐Sánchez, P., Rodríguez-Velasco, F. J., & Pedrera‐Zamorano, J. D. (2012) · Nutrients · doi:10.3390/nu5010010 · Cited by 47
Long-Term High Urinary Potential Renal Acid Load and Low Nitrogen Excretion Predict Reduced Diaphyseal Bone Mass and Bone Size in Children
Remer, T., Manz, F., Alexy, U., Schöenau, E., Wudy, S. A., & Shi, L. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1005 · Cited by 47
Dietary Acid Load Is Not Associated with Lower Bone Mineral Density Except in Older Men,
McLean, R. R., Qiao, N., Broe, K. E., Tucker, K. L., Casey, V. A., Cupples, L. A., Kiel, D. P., & Hannan, M. T. (2011) · Journal of Nutrition · doi:10.3945/jn.110.135806 · Cited by 47
Self-citation
The Association Between Protein Intake by Source and Osteoporotic Fracture in Older Men: A Prospective Cohort Study
Langsetmo, L., Shikany, J. M., Cawthon, P. M., Cauley, J. A., Taylor, B. C., Vo, T., Bauer, D. C., ORWOLL, E. S., Schousboe, J. T., & Ensrud, K. E. (2016) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3058 · Cited by 47
Chondroitin sulfate and other sulfate containing chondroprotective agents may exhibit their effects by overcoming a deficiency of sulfur amino acids
Cordoba, F., & Nimni, M. E. (2003) · Osteoarthritis and Cartilage · doi:10.1016/s1063-4584(02)00351-5 · Cited by 47
Plenary Lecture: Strategies for skeletal health in the elderly
Eastell, R., & Lambert, H. (2002) · Proceedings of The Nutrition Society · doi:10.1079/pns2002160 · Cited by 46
The association between body mass index and osteoporosis in a Taiwanese population: a cross-sectional and longitudinal study
Chiu, C.-T., Lee, J., Lu, C., Huang, S., Chen, S., & Geng, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-59159-4 · Cited by 51
Calcium Metabolism and Correcting Calcium Deficiencies
Emkey, R. D., & Emkey, G. R. (2012) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2012.04.019 · Cited by 46
Comparison of 2 weight-loss diets of different protein content on bone health: a randomized trial
Jesudason, D. R., Nordin, B. C., Keogh, J. B., & Clifton, P. M. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.058586 · Cited by 44
Perspectives on using nonhuman primates to understand the etiology and treatment of postmenopausal osteoporosis.
Brommage, R. (2001) · PubMed · Cited by 44
Four-Year Review of Burns as an Etiologic Factor in the Development of Long Bone Fractures in Pediatric Patients
Mayes, T., Gottschlich, M. M., Scanlon, J., & Warden, G. D. (2003) · Journal of Burn Care & Rehabilitation · doi:10.1097/01.bcr.0000085844.84144.e0 · Cited by 43
Animal, Plant, Collagen and Blended Dietary Proteins: Effects on Musculoskeletal Outcomes
Deane, C. S., Bass, J. J., Crossland, H., Phillips, B. E., & Atherton, P. J. (2020) · Nutrients · doi:10.3390/nu12092670 · Cited by 48
Zinc increases the effects of essential amino acids-whey protein supplements in frail elderly
Rodondi, A., Ammann, P., Ghilardi-Beuret, S., & Rizzoli, R. (2009) · The journal of nutrition health & aging · doi:10.1007/s12603-009-0099-5 · Cited by 42
Effects of protein on the calcium economy
Heaney, R. P. (2007) · International Congress Series · doi:10.1016/j.ics.2006.08.025 · Cited by 42
Dietary Protein Intake in Relation to the Risk of Osteoporosis in Middle-Aged and Older Individuals: A Cross-Sectional Study
Zhang, Y.-W., Cao, M.-M., Li, Y.-J., Dai, G., Lu, P., Zhang, M., Bai, L.-Y., Chen, X.-X., Shi, L., Zhang, C., et al. (2022) · The Journal of Nutrition, Health & Aging · doi:10.1007/s12603-022-1748-1 · Cited by 38
The pathophysiology of osteoporotic hip fracture
Metcalfe, D. (2020) · McGill Journal of Medicine · doi:10.26443/mjm.v11i1.410 · Cited by 42
Is protein intake associated with bone mineral density in young women?
Beasley, J. M., Ichikawa, L., Ange, B. A., Spangler, L., LaCroix, A. Z., Ott, S. M., & Scholes, D. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28728 · Cited by 41
The influence of vegetarian and vegan diets on the state of bone mineral density in humans
Galchenko, A. V., Гаппарова, К. М., & Sidorova, E. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1996330 · Cited by 42
Calcium, protein, and fruit and vegetables as dietary determinants of bone health
New, S. A., & Millward, D. J. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.5.1340 · Cited by 41
Adherence to a Mediterranean Diet and Bone Mineral Density in Spanish Premenopausal Women
Pérez-Rey, J., Roncero‐Martín, R., Rico‐Martín, S., Rey‐Sánchez, P., Pedrera‐Zamorano, J. D., Pedrera-Canal, M., López‐Espuela, F., & García, J. M. L. (2019) · Nutrients · doi:10.3390/nu11030555 · Cited by 40
Nutritional Influences on Bone Health
Burckhardt, P., Dawson-Hughes, B. F., & Weaver, C. M. (2013) · Springer eBooks · doi:10.1007/978-1-4471-2769-7 · Cited by 40
Self-citation
Long-Term Intake of a High-Protein Diet with or without Potassium Citrate Modulates Acid-Base Metabolism, but Not Bone Status, in Male Rats
Mardon, J., Habauzit, V., Trzeciakiewicz, A., Davicco, M.-J., Lebecque, P., Mercier, S., Tressol, J.-C., Horcajada, M.-N., Demigné, C., & Coxam, V. (2008) · Journal of Nutrition · doi:10.1093/jn/138.4.718 · Cited by 40
Dietary protein intake in elderly women: association with muscle and bone mass.
Genaro, P. D. S., Pinheiro, M. D. M., Szejnfeld, V., & Martini, L. (2015) · Nutrition in clinical practice · doi:10.1177/0884533614545404 · Cited by 45
Race and Diet Interactions in the Acquisition, Maintenance, and Loss of Bone
Walker, M. D., Novotny, R., Bilezikian, J. P., & Weaver, C. M. (2008) · Journal of Nutrition · doi:10.1093/jn/138.6.1256s · Cited by 39
Calcium, vitamin D, and nutrition in elderly adults
Nieves, J. W. (2003) · Clinics in Geriatric Medicine · doi:10.1016/s0749-0690(02)00073-3 · Cited by 39
Association of pelvic organ prolapse and fractures in postmenopausal women
Pal, L., Hailpern, S. M., Santoro, N. F., Freeman, R., Barad, D. H., Kipersztok, S., Barnabei, V. M., & Wassertheil-Smoller, S. W. (2008) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e3181151444 · Cited by 39
Association of total protein intake with bone mineral density and bone loss in men and women from the Framingham Offspring Study
Sahni, S., Broe, K. E., Tucker, K. L., McLean, R. R., Kiel, D. P., Cupples, L. A., & Hannan, M. T. (2013) · Public Health Nutrition · doi:10.1017/s1368980013002875 · Cited by 38
Self-citation
Dietary Patterns in Relation to Bone Mineral Density Among Menopausal Iranian Women
Karamati, M., Jessri, M., Shariati-Bafghi, S.-E., & Rashidkhani, B. (2012) · Calcified Tissue International · doi:10.1007/s00223-012-9608-3 · Cited by 37

Authors: Hannan, M. T., Tucker, K. L., Dawson-Hughes, B., Cupples, L. A., Felson, D. T., & Kiel, D. P.
Affiliations: Boston University (US)
Tufts University (US)
Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, U.S.A.
Harvard University (US)
Corresponding author: Hannan, Marian T.
ORCID: Hannan, Marian T.
Tucker, Katherine L.
Cupples, L. Adrienne
Felson, David T.
Kiel, Douglas P.
Venue: Journal of Bone and Mineral Research
Publisher: Oxford University Press (OUP)
Published: 2000-12-01
Volume: 15
Issue: 12
Pages: 2504-2512
ISSN: 0884-0431 (ISSN-L)
1523-4681
DOI: 10.1359/jbmr.2000.15.12.2504
OpenAlex: W2087658867
Cited by: 536
References: 59
Citations by year: 2026: 4 · 2025: 7 · 2024: 15 · 2023: 14 · 2022: 9 · 2021: 12 · 2020: 21 · 2019: 17 · 2018: 17 · 2017: 21 · 2016: 15 · 2015: 20 · 2014: 29 · 2013: 30 · 2012: 14
FWCI: 19.72
Type: journal article
Language: en
Open access: closed
Licence: academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
Locations: Journal of Bone and Mineral Research (publishedVersion)
PubMed (publishedVersion)
Funders: Arthritis Foundation
National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR-20613, R01 AR/AG 41398, P60AR020613)
Topics: Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords: dietary protein, bone loss, bone mineral density, older adults, animal protein, calcium balance, osteoporosis, sex differences, femoral bone, radial bone
MeSH terms: Adult, Dietary Proteins, Female, Femur, Humans, Longitudinal Studies, Male, Middle Aged, Osteoporosis, Surveys and Questionnaires, Radius, Spine, Time Factors, Absorptiometry, Photon, Bone Density, Osteoporosis, Postmenopausal

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Effect of Dietary Protein on Bone Loss in Elderly Men and Women: The Framingham Osteoporosis Study

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks