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Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infrared

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Maier, John S., Walker, Scott A., Fantini, Sergio, Franceschini, Maria Angela, Gratton, Enrico·1994·Optics Letters

Abstract

Tissue glucose levels affect the refractive index of the extracellular fluid. The difference in refractive index between the extracellular fluid and the cellular components plays a role in determining the reduced scattering coefficient (micro(s)') of tissue. Hence a physical correlation may exist between the reduced scattering coefficient and glucose concentration. We have designed and constructed a frequency-domain near-infrared tissue spectrometer capable of measuring the reduced scattering coefficient of tissue with enough precision to detect changes in glucose levels in the physiological and pathological range.

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Metadata

Authors
Maier, J. S., Walker, S. A., Fantini, S., Franceschini, M. A., & Gratton, E.
Venue
Optics Letters
Published
1994-12-15
Volume
19
Issue
24
Pages
2062
ISSN
  • 0146-9592 (ISSN-L)
  • 1539-4794
OpenAlex
W1998548833
Cited by
318
References
0
FWCI
8.54
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infrared. https://app.cochat.ai/papers/10.1364/ol.19.002062
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Maier, J. S., Walker, S. A., Fantini, S., Franceschini, M. A., & Gratton, E. (1994). Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infrared. Optics Letters. https://doi.org/10.1364/ol.19.002062

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