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Determination of the refractive index of highly scattering human tissue by optical coherence tomography

Tearney, G. J., Brezinski, M. E., Bouma, B. E., Hee, M. R., Southern, J. F., Fujimoto, J. G.·1995·Optics Letters

Abstract

We describe two new techniques, based on optical coherence tomography (OCT), for determining the refractive index of highly scattering human tissue. We obtained refractive indices of in vitro human tissue, using OCT to measure the physical and optical path lengths of the sample. We obtained measurements of the refractive index of in vitro and in vivo human tissue, using OCT to track the focal length shift that results from translating the focus along the optic axis within the tissue. The refractive indices of human skin, adipose, and muscle were measured and compared with previously published estimates.

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Metadata

Authors
Tearney, G. J., Brezinski, M. E., Bouma, B. E., Hee, M. R., Southern, J. F., & Fujimoto, J. G.
Venue
Optics Letters
Published
1995-11-01
Volume
20
Issue
21
Pages
2258
ISSN
  • 0146-9592 (ISSN-L)
  • 1539-4794
OpenAlex
W2125044170
Cited by
562
References
0
FWCI
8.09
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Determination of the refractive index of highly scattering human tissue by optical coherence tomography. https://app.cochat.ai/papers/10.1364/ol.20.002258
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Tearney, G. J., Brezinski, M. E., Bouma, B. E., Hee, M. R., Southern, J. F., & Fujimoto, J. G. (1995). Determination of the refractive index of highly scattering human tissue by optical coherence tomography. Optics Letters. https://doi.org/10.1364/ol.20.002258

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.