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Determination of the refractive index of highly scattering human tissue by optical coherence tomography
Abstract
We describe two new techniques, based on optical coherence tomography (OCT), for determining the refractive index of highly scattering human tissue. We obtained refractive indices of in vitro human tissue, using OCT to measure the physical and optical path lengths of the sample. We obtained measurements of the refractive index of in vitro and in vivo human tissue, using OCT to track the focal length shift that results from translating the focus along the optic axis within the tissue. The refractive indices of human skin, adipose, and muscle were measured and compared with previously published estimates.
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Citations
Cited by
Kienle, A., & Patterson, M. S. (1997) · Journal of the Optical Society of America A · doi:10.1364/josaa.14.000246 · Cited by 474
Optical properties of human skin
Lister, T., Wright, P. A., & Chappell, P. H. (2012) · Journal of Biomedical Optics · doi:10.1117/1.jbo.17.9.090901 · Cited by 467
Meglinski, I. V., & Matcher, S. J. (2002) · Physiological Measurement · doi:10.1088/0967-3334/23/4/312 · Cited by 408
Haruna, M., Ohmi, M., Mitsuyama, T., Tajiri, H., Maruyama, H., & Hashimoto, M. (1998) · Optics Letters · doi:10.1364/ol.23.000966 · Cited by 142
Silver, R., Helms, A., Fu, W., Wang, H., Diaconu, D., Loyd, C. M., Rollins, A. M., & Ward, N. L. (2012) · Skin Research and Technology · doi:10.1111/j.1600-0846.2011.00558.x · Cited by 16
Metadata
- Authors
- Tearney, G. J., Brezinski, M. E., Bouma, B. E., Hee, M. R., Southern, J. F., & Fujimoto, J. G.
- Venue
- Optics Letters
- Publisher
- Optica Publishing Group
- Published
- 1995-11-01
- Volume
- 20
- Issue
- 21
- Pages
- 2258
- ISSN
- 0146-9592 (ISSN-L)
- 1539-4794
- OpenAlex
- W2125044170
- Cited by
- 562
- References
- 0
- FWCI
- 8.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tearney, G. J., Brezinski, M. E., Bouma, B. E., Hee, M. R., Southern, J. F., & Fujimoto, J. G. (1995). Determination of the refractive index of highly scattering human tissue by optical coherence tomography. Optics Letters. https://doi.org/10.1364/ol.20.002258
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