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Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography
Open accessAbstract
Using a low-coherence Michelson interferometer, we measure two-dimensional images of optical birefringence in bovine tendon as a function of depth. Polarization-sensitive detection of the signal formed by interference of backscattered light from the sample and a mirror in the reference arm give the optical phase delay between light that is propagating along the fast and slow axes of the birefringent tendon. Images showing the change in birefringence in response to laser irradiation are presented. The technique permits rapid noncontact investigation of tissue structural properties through two-dimensional imaging of birefringence.
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Citations
Cited by
Imaging skin pathology with polarized light
Jacques, S. L., Ramella-Roman, J. C., & Lee, K. (2002) · Journal of Biomedical Optics · doi:10.1117/1.1484498 · Cited by 582
Optical coherence tomography – current and future applications
Adhi, M., & Duker, J. S. (2013) · Current Opinion in Ophthalmology · doi:10.1097/icu.0b013e32835f8bf8 · Cited by 567
Hitzenberger, C., Goetzinger, E., Sticker, M., Pircher, M., & Fercher, A. (2001) · Optics Express · doi:10.1364/oe.9.000780 · Cited by 391
Spectral-domain phase microscopy
Choma, M. A., Ellerbee, A. K., Yang, C., Creazzo, T. L., & Izatt, J. A. (2005) · Optics Letters · doi:10.1364/ol.30.001162 · Cited by 342
Baumann, B., Baumann, S. O., Konegger, T., Pircher, M., Götzinger, E., Schlanitz, F., Schütze, C., Sattmann, H., Litschauer, M., Schmidt-Erfurth, U., et al. (2012) · Biomedical Optics Express · doi:10.1364/boe.3.001670 · Cited by 163
Metadata
- Authors
- de Boer, J. F., Milner, T. E., van Gemert, M. J. C., & Nelson, J. S.
- Venue
- Optics Letters
- Publisher
- Optica Publishing Group
- Published
- 1997-06-15
- Volume
- 22
- Issue
- 12
- Pages
- 934
- ISSN
- 0146-9592 (ISSN-L)
- 1539-4794
- OpenAlex
- W2164607765
- Cited by
- 883
- References
- 0
- FWCI
- 18.51
- Type
- journal article
- Language
- en
- Open access
- green
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- de Boer, J. F., Milner, T. E., van Gemert, M. J. C., & Nelson, J. S. (1997). Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography. Optics Letters. https://doi.org/10.1364/ol.22.000934
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