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Cited by 215

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Evaluating cutaneous photoaging by use of multiphoton fluorescence and second-harmonic generation microscopy

Lin, Sung-Jan, Wu, Ruei-Jr, Tan, Hsin-Yuan, Lo, Wen, Lin, Wei-Chou, Young, Tai-Horng, Hsu, Chih-Jung, Chen, Jau-Shiuh, Jee, Shiou-Hwa, Dong, Chen-Yuan·2005·Optics Letters

Abstract

The photoaging process of facial skin is investigated by use of multiphoton fluorescence and second-harmonic generation (SHG) microscopy. We obtain the autofluorescence (AF) and SHG images of the superficial dermis from the facial skin of three patients aged 20, 40, and 70 years. The results show that areas of AF increase with age, whereas areas of SHG decrease with age. The results are consistent with the histological findings in which collagen is progressively replaced by elastic fibers. The AF and SHG changes in photoaging are quantified by a SHG to autofluorescence aging index of dermis (SAAID). Our results suggest that SAAID can be a good indicator of the severity of photoaging.

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Metadata

Authors
Lin, S.-J., Wu, R.-J., Tan, H.-Y., Lo, W., Lin, W.-C., Young, T.-H., Hsu, C.-J., Chen, J.-S., Jee, S.-H., & Dong, C.-Y.
Venue
Optics Letters
Published
2005-09-01
Volume
30
Issue
17
Pages
2275
ISSN
  • 0146-9592 (ISSN-L)
  • 1539-4794
OpenAlex
W2061457768
Cited by
215
References
1
FWCI
14.25
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Evaluating cutaneous photoaging by use of multiphoton fluorescence and second-harmonic generation microscopy. https://app.cochat.ai/papers/10.1364/ol.30.002275
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Lin, S.-J., Wu, R.-J., Tan, H.-Y., Lo, W., Lin, W.-C., Young, T.-H., Hsu, C.-J., Chen, J.-S., Jee, S.-H., & Dong, C.-Y. (2005). Evaluating cutaneous photoaging by use of multiphoton fluorescence and second-harmonic generation microscopy. Optics Letters. https://doi.org/10.1364/ol.30.002275

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