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Cited by 280

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

In vivo assessment of human skin aging by multiphoton laser scanning tomography

Koehler, Martin Johannes, König, Karsten, Elsner, Peter, Bückle, Rainer, Kaatz, Martin·2006·Optics Letters

Abstract

Changes of dermal collagen and elastin content are characteristic for skin aging as well as for pathological skin conditions. To evaluate these changes, we used in vivo multiphoton laser tomography to measure two-photon excited autofluorescence (AF) and second harmonic generation (SHG). We tested 18 patients of all ages and calculated the SHG-to-AF aging index of dermis (SAAID). We observed a negative relationship between the SAAID and age, which was accelerated for the female (n=7) subgroup. The current findings are the first in vivo demonstration of this relationship, and they show that specific characteristics of aged skin such as the ratio of extracellular matrix components collagen and elastin can be evaluated by in vivo AF and SHG measurements using near-IR femtosecond laser pulses.

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Metadata

Authors
Koehler, M. J., König, K., Elsner, P., Bückle, R., & Kaatz, M.
Venue
Optics Letters
Published
2006-09-11
Volume
31
Issue
19
Pages
2879
ISSN
  • 0146-9592 (ISSN-L)
  • 1539-4794
OpenAlex
W1994860701
Cited by
280
References
7
FWCI
9.45
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: In vivo assessment of human skin aging by multiphoton laser scanning tomography. https://app.cochat.ai/papers/10.1364/ol.31.002879
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Koehler, M. J., König, K., Elsner, P., Bückle, R., & Kaatz, M. (2006). In vivo assessment of human skin aging by multiphoton laser scanning tomography. Optics Letters. https://doi.org/10.1364/ol.31.002879

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.