Functional Dissection of an Innate Immune Response by a Genome-Wide RNAi Screen
Foley, Edan, O'Farrell, Patrick H·2004·PLoS Biology
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- Cell linesLucy Cherbas, Lei Gong · 2014 · Methods
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- Non-vertebrate hosts in the analysis of host–pathogen interactionsMarion S. Dorer, Ralph R. Isberg · 2006 · Microbes and Infection
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- Identification of Drosophila Zfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference ScreenIiro Taneli Helenius, Ryan J Haake, Yong-Jae Kwon, Jennifer A Hu, Thomas Krupinski, S. Marina Casalino‐Matsuda, Peter H. S. Sporn, Jacob Iasha Sznajder, Greg J. Beitel · 2015 · The Journal of Immunology
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- Specific Calcineurin Isoforms Are Involved in Drosophila Toll Immune SignalingYi‐Xian Li, Pascale F. Dijkers · 2014 · The Journal of Immunology
- Functional genomic analysis of the Drosophila immune response.S. Valanne · 2014 · Developmental and Comparative Immunology
- Exploiting Cell-To-Cell Variability To Detect Cellular PerturbationsGautam Dey, Gagan D. Gupta, Balaji Ramalingam, Mugdha Sathe, Satyajit Mayor, Mukund Thattai · 2014 · PLoS ONE
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- Interactions of DNR1 with the apoptotic machinery of<i>Drosophila</i>melanogasterPrimrose, David A., Chaudhry, Sidharth, Johnson, A. George D., Hrdlicka, Adam, Schindler, Anja, Tran, Dave, Foley, Edan · 2007 · Journal of Cell Science
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- Costs and genomic aspects of Drosophila immunity to parasites and pathogensAlex R. Kraaijeveld, Bregje Wertheim · 2009 · Oxford University Press eBooks
- F as‐associated factor 1 plays a negative regulatory role in the antibacterial immunity of L ocusta migratoriaZ. He, P. Wang, Hong‐Juan Shi, Feng‐Ling Si, Youjin Hao, B. Chen · 2013 · Insect Molecular Biology
- Development on Citrus medica infected with ‘Candidatus Liberibacter asiaticus’ has sex-specific and -nonspecific impacts on adult Diaphorina citri and its endosymbiontsLaurynne C. Coates, Jaclyn E. Mahoney, John S. Ramsey, EricaRose Warwick, Richard S. Johnson, Michael J. MacCoss, Stuart B. Krasnoff, Kevin J. Howe, Kathy Moulton, Surya Saha et al. · 2020 · PLoS ONE
- The multilayered innate immune defense of the gutLaure El Chamy, Nicolas Matt, Monde McMillan Ntwasa, Jean‐Marc Reichhart · 2015 · Biomedical Journal
- A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genesEnzo Mameli, George-Rafael Samantsidis, Raghuvir Viswanatha, Hyeogsun Kwon, David R. Hall, Matthew Butnaru, Yanhui Hu, Stephanie Elizabeth Mohr, Norbert Perrimon, Ryan C. Smith · 2025 · Nature Communications
- Recruitment of Peroxin 14 to lipid droplets affects lipid storage in DrosophilaMatthew Anderson‐Baron, Kazuki Ueda, Julie Haskins, Sarah C. Hughes, Andrew James Simmonds · 2022 · Journal of Cell Science
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- RNAi Screening of Drosophila (Sophophora) melanogaster S2 Cells for Ricin Sensitivity and ResistanceVidya S. Pawar, Antara De, Laura Briggs, Mahmoud M Omar, Sean T. Sweeney, Janet M. Lord, Lynne M. Roberts, Robert A. Spooner, Kevin G. Moffat · 2011 · SLAS DISCOVERY
- RNAi Applications in Target ValidationAntonis Kourtidis, Cheryl Eifert, Douglas S. Conklin · 2007 · Springer eBooks
- The Little Fly that Could: Wizardry and Artistry of Drosophila GenomicsRadoslaw Kamil Ejsmont, Bassem A. Hassan · 2014 · Genes
- A fat body transcriptome analysis of the immune responses of Rhodnius prolixus to artificial infections with bacteriaNicolás Salcedo-Porras, Pedro Lagerblad de Oliveira, Alessandra A. Guarneri, Carl A. Lowenberger · 2022 · Parasites & Vectors
- Coevolution of hytrosaviruses and host immune responsesHenry M. Kariithi, Drion G. Boucias, Edwin Kimathi Murungi, Irene Kasindi Meki, Güler Demirbas Uzel, Monique M. van Oers, Marc J. B. Vreysen, Adly M. M. Abd‐Alla, Just M. Vlak · 2018 · BMC Microbiology
- A protein network-guided screen for cell cycle regulators in DrosophilaStephen T. Guest, Jingkai Yu, Dongmei Liu, Julie A. Hines, Maria A Kashat, Russell L. Finley · 2011 · BMC Systems Biology
- RNAi-Based Identification of Gene-Specific Nuclear Cofactor Networks Regulating Interleukin-1 Target GenesJohanna Meier‐Soelch, Liane Jurida, Axel Weber, Doris Newel, Johnny Kim, Thomas W Braun, Michael Lienhard Schmitz, Michael Kracht · 2018 · Frontiers in Immunology
- 5,000 RNAi experiments on a chipBen Lehner, Andrew G. Fraser · 2004 · Nature Methods
- Weighted single-step genome-wide association study and functional enrichment analyses for gastrointestinal nematode resistance traits in Santa Ines sheepNedenia Bonvino Stafuzza, Ana Clara Lacerda Freitas, Marina Bueno Mioto, Rafael Medeiros de Oliveira Silva, Breno de Oliveira Fragomeni, Victor Breno Pedrosa, Ricardo Lopes Dias da Costa, Cláudia Cristina Paro de Paz · 2023 · Veterinary Parasitology
- Drosophila eIF3f1 mediates host immune defense by targeting dTak1Yixuan Hu, Fanrui Kong, Huimin Guo, Yongzhi Hua, Yangyang Zhu, Chuchu Zhang, Abdul Qadeer, Yihua Xiao, Qingshuang Cai, Shanming Ji · 2024 · EMBO Reports
- Functional Regulatory Divergence of the Innate Immune System in Interspecific Drosophila HybridsErin M. Hill‐Burns, Andrew G. Clark · 2010 · Molecular Biology and Evolution
- A tandem death effector domain-containing protein inhibits the IMD signaling pathway via forming amyloid-like aggregates with the caspase-8 homolog DREDDJie Hong Hu, Xinyi Wang, Xiaoyi Xiao, Chang Sun, Qingyou Xia, Fei Wang · 2019 · Insect Biochemistry and Molecular Biology
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- PPARα siRNA–Treated Expression Profiles Uncover the Causal Sufficiency Network for Compound-Induced Liver HypertrophyXudong Dai, Angus T. De Souza, Hongyue A. Dai, David L Lewis, Changkyu Lee, Andy G Spencer, Hans Herweijer, Jim E Hagstrom, Peter S. Linsley, Douglas E. Bassett et al. · 2007 · PLoS Computational Biology
- Relish-mediated C2H2 zinc finger protein IMZF restores Drosophila immune homeostasis via inhibiting the transcription of Imd/Tak1Hongjian Zhou, Li Liu, Yujia Pang, Yina Xu, Jing Wu, Fei Ma, Ping Jin, Xue Zhou · 2024 · Insect Biochemistry and Molecular Biology
- Experimental Models to Study the Pathogenesis and Treatment of MucormycosisRonen Ben‐Ami · 2024 · Journal of Fungi
- Functional characterization of the NF‐κB transcription factor gene REL2 from Anopheles gambiaeNgô Thị Hoa, Liangbiao Zheng · 2007 · Insect Science
- Insect Immunity: From Systemic to Chemosensory Organs ProtectionEvelyne Einhorn, Jean‐Luc Imler · 2019 · Springer eBooks
- What RNAi screens in model organisms revealed about microbicidal response in mammals?Prasad Abnave, Filippo Conti, Cédric Torre, Éric Ghigo · 2015 · Frontiers in Cellular and Infection Microbiology
- The complexity of Drosophila innate immunityAnk Reumer, Tom Van Loy, Liliane Schoofs · 2010 · Invertebrate survival journal
- Identification of Aadnr1 , a novel gene related to innate immunity and apoptosis in Aedes albopictusXiaomei Li, Kun Meng, Jialu Qiao, Hao Liu, Chunyan Zhong, Qingzhen Liu · 2016 · Gene
- Hemolymph protein profiles of subterranean termite Reticulitermes flavipes challenged with methicillin resistant Staphylococcus aureus or Pseudomonas aeruginosaYuan Zeng, Xing Ping Hu, Guanqun Cao, Sang‐Jin Suh · 2018 · Scientific Reports
- SPS1 deficiency-triggered PGRP-LC and Toll expression controls innate immunity in Drosophila S2 cellsTack-Jin Yoo, Myoung Sup Shim, Jeyoung Bang, Jin‐Hong Kim, Byeong Jae Lee · 2022 · Biology Open
- Neuron navigators: A novel frontier with physiological and pathological implicationsParth Sandeep, Poonam Sharma, Kanishk Luhach, Neerupma Dhiman, Harsha Kharkwal, Bhupesh Sharma · 2023 · Molecular and Cellular Neuroscience
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- Adding a Chemical Biology Twist to CRISPR ScreeningShiying Huang, Jeremy M. Baskin · 2022 · Israel Journal of Chemistry
- Systems-level analysis of host–pathogen interaction using RNA interferenceSimone Eicher, Christoph Dehio · 2013 · New Biotechnology
- Phenomics of the Laboratory MouseJohn M. Hancock, Michael S. Dobbie · 2014 · CRC Press eBooks
- Analyzing the Structure, Function and Information Flow in Signaling Networks using Quantitative Cellular SignaturesMeghana M. Kulkarni, Norbert Perrimon · 2012 · Elsevier eBooks
- RNAi depleted Drosophila cell extracts to dissect signaling pathways leading to actin polymerizationLamia Bouslama‐Oueghlani, Arnaud Échard, Daniel Louvard, Alexis M. Gautreau · 2007 · Journal of Biochemical and Biophysical Methods
- Corrigendum2007 · Insect Science