The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Calories Do Not Explain Extension of Life Span by Dietary Restriction in Drosophila
Open accessAbstract
Dietary restriction (DR) extends life span in diverse organisms, including mammals, and common mechanisms may be at work. DR is often known as calorie restriction, because it has been suggested that reduction of calories, rather than of particular nutrients in the diet, mediates extension of life span in rodents. We here demonstrate that extension of life span by DR in Drosophila is not attributable to the reduction in calorie intake. Reduction of either dietary yeast or sugar can reduce mortality and extend life span, but by an amount that is unrelated to the calorie content of the food, and with yeast having a much greater effect per calorie than does sugar. Calorie intake is therefore not the key factor in the reduction of mortality rate by DR in this species.
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Promoting Health and Longevity through Diet: From Model Organisms to Humans
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Self-citationLifespan and reproduction in Drosophila : New insights from nutritional geometry
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Metadata
- Authors
- Mair, W., Piper, M. D. W., & Partridge, L.
- Venue
- PLoS Biology
- Publisher
- Public Library of Science (PLoS)
- Published
- 2005-05-31
- Volume
- 3
- Issue
- 7
- Pages
- e223
- ISSN
- 1544-9173 (ISSN-L)
- 1545-7885
- OpenAlex
- W2030732918
- Cited by
- 522
- References
- 56
- FWCI
- 6.58
- Type
- journal article
- Language
- en
- Open access
- gold
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- Mair, W., Piper, M. D. W., & Partridge, L. (2005). Calories Do Not Explain Extension of Life Span by Dietary Restriction in Drosophila. PLoS Biology. https://doi.org/10.1371/journal.pbio.0030223
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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