The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age

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2. Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors
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3. FoxP1 promotes midbrain identity in embryonic stem cell‐derived dopamine neurons by regulating Pitx3
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4. Crosstalk of Intercellular Signaling Pathways in the Generation of Midbrain Dopaminergic Neurons In Vivo and from Stem Cells
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5. Neuroprotective Transcription Factors in Animal Models of Parkinson Disease
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6. Directed Expression of Gata2, Mash1, and Foxa2 Synergize to Induce the Serotonergic Neuron Phenotype During In Vitro Differentiation of Embryonic Stem Cells
   Christian Maximilian Nefzger, John M. Haynes, Colin William Pouton · 2011 · Stem Cells
7. Transcriptomic profiling of the ventral tegmental area and nucleus accumbens in rhesus macaques following long-term cocaine self-administration
   Eric J. Vallender, Dharmendra B. Goswami, Nina M. Shinday, Susan V. Westmoreland, Wei‐Dong Yao, James K. Rowlett · 2017 · Drug and Alcohol Dependence
8. Will Stem Cell Biology Generate New Therapies for Parkinson's Disease?
   Ron D. G. McKay, Raja Kittappa · 2008 · Neuron
9. Ectopic Wnt/Beta–Catenin Signaling Induces Neurogenesis in the Spinal Cord and Hindbrain Floor Plate
   Milan Joksimovic, Meera J. Patel, Makoto Mark Taketo, Randy L. Johnson, Rajeshwar B. Awatramani · 2012 · PLoS ONE
10. Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons
    R Rössler, Erik Boddeke, Sjef C.V.M. Copray · 2010 · Neuroscience
11. Toward Spatial Identities in Human Brain Organoids-on-Chip Induced by Morphogen-Soaked Beads
    Lihi Ben‐Reuven, Orly Reiner · 2020 · Bioengineering
12. Assessing the molecular genetics of the development of executive attention in children: focus on genetic pathways related to the anterior cingulate cortex and dopamine
    Karin Cecilia Brocki, Suzanne M. Clerkin, Kevin G. Guise, Jin Fan, John Fossella · 2009 · Neuroscience
13. Role of Nurr1 in the Generation and Differentiation of Dopaminergic Neurons from Stem Cells
    Eva Rodríguez‐Traver, Óscar Solís, Eva Díaz‐Guerra, Óscar Ortiz, Eva Vergaño‐Vera, Héctor R. Méndez‐Gómez, Patricia García‐Sanz, Rosario Moratalla, Carlos Vicario‐Abejón · 2015 · Neurotoxicity Research
14. Effect of chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin in female rats on ovarian gene expression
    Kelli Elizabeth Valdez, Zhanquan Shi, Alison Y. Ting, Brian K. Petroff · 2009 · Reproductive Toxicology
15. Nurr1 blocks the mitogenic effect of FGF ‐2 and EGF , inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic‐ GABA ergic neuronal phenotypes
    Eva Vergaño‐Vera, Eva Díaz‐Guerra, Eva Rodríguez‐Traver, Héctor R. Méndez‐Gómez, Óscar Solís, Jaime Pignatelli, James M. Pickel, Sang‐Hun Lee, Rosario Moratalla, Carlos Vicario‐Abejón · 2014 · Developmental Neurobiology
16. Cerebral dopamine neurotrophic factor is essential for enteric neuronal development, maintenance, and regulation of gastrointestinal transit
    Alcmène Chalazonitis, ZhiShan Li, Tuan Duc Pham, Jason Chiashane Chen, Meenakshi Rao, Päivi Lindholm, Märt Saarma, Maria Lindahl, Michael David Gershon · 2020 · The Journal of Comparative Neurology
17. Engrailed signaling in axon guidance and neuron survival
    Julia Fuchs, Olivier Stettler, Daniel Alvarez‐Fischer, Alain Prochiantz, Kenneth L. Moya, Rajiv L. Joshi · 2012 · European Journal of Neuroscience
18. Maternal genotype influences behavioral development of 3×Tg-AD mouse pups
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19. Lmx1a Allows Context-Specific Isolation of Progenitors of GABAergic or Dopaminergic Neurons During Neural Differentiation of Embryonic Stem Cells
    Christian Maximilian Nefzger, Colin T. E. Su, Stewart A. Fabb, Brigham J. Hartley, Siew J. Beh, Wendy Rong Zeng, John M. Haynes, Colin William Pouton · 2012 · Stem Cells
20. Parallel roles of transcription factors dFOXO and FER2 in the development and maintenance of dopaminergic neurons
    Damla Tas, Luca Stickley, Federico Miozzo, Rafael Koch, Nicolas Loncle, Virginie Sabado, Bettina Gnägi, Emi Nagoshi · 2018 · PLoS Genetics
21. Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells
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22. Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson’s disease
    Alcmène Chalazonitis, Meenakshi Rao, David L. Sulzer · 2022 · npj Parkinson s Disease
23. Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells
    Mark Denham, Lachlan H. Thompson, Jessie Leung, Alice Pébay, Anders Björklund, Mirella Dottori · 2010 · Stem Cells
24. In vitro generation of mature midbrain-type dopamine neurons by adjusting exogenous Nurr1 and Foxa2 expressions to their physiologic patterns
    Taeho Kim, Jae‐Jin Song, Lesly Puspita, Parvin Valiulahi, Jaewon Shim, Sang‐Hun Lee · 2017 · Experimental & Molecular Medicine
25. Dopaminergic Neurons Transplanted Using Cell‐Instructive Biomaterials Alleviate Parkinsonism in Rodents
    Maroof M. Adil, Antara T. Rao, Gokul N. Ramadoss, Nicole E. Chernavsky, Rishikesh U. Kulkarni, Evan W. Miller, Sanjay Kumar, David V. Schaffer · 2018 · Advanced Functional Materials
26. Forkhead Box Protein A2 (FOXA2) Protein Stability and Activity Are Regulated by Sumoylation
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27. Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain
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28. Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus
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29. Spotting-based differentiation of functional dopaminergic progenitors from human pluripotent stem cells
    Jisun Kim, Jeha Jeon, Bin Song, Nayeon Lee, Sanghyeok Ko, Young Cha, Pierre R Leblanc, Hyemyung Seo, Kwang‐Soo Kim · 2022 · Nature Protocols
30. Embryonic development of selectively vulnerable neurons in Parkinson’s disease
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31. Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in vivo
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33. Protocols for Generating ES Cell-Derived Dopamine Neurons
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34. Not lost in translation
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35. Meta-Analysis of Transcriptome Data Related to Hippocampus Biopsies and iPSC-Derived Neuronal Cells from Alzheimer’s Disease Patients Reveals an Association with FOXA1 and FOXA2 Gene Regulatory Networks
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36. Foxa1 is essential for development and functional integrity of the subthalamic nucleus
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37. N‐cadherin regulates the proliferation and differentiation of ventral midbrain dopaminergic progenitors
    Fumi Sakane, Yasunori Miyamoto · 2013 · Developmental Neurobiology
38. Expression of Early Developmental Markers Predicts the Efficiency of Embryonic Stem Cell Differentiation into Midbrain Dopaminergic Neurons
    Ahmad Salti, Roxana Nat, Sonya Carvalho Neto, Zoe Puschban, Gregor Karl Wenning, Georg Dechant · 2012 · Stem Cells and Development
39. Characterization of axon guidance cue sensitivity of human embryonic stem cell-derived dopaminergic neurons
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40. Impact of Sleep–Wake-Associated Neuromodulators and Repetitive Low-Frequency Stimulation on Human iPSC-Derived Neurons
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41. Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor
    Federico Miozzo, Eva P. Valencia-Alarcón, Luca Stickley, Michaëla Majcin Dorcikova, Francesco Petrelli, Damla Tas, Nicolas Loncle, Irina Nikonenko, Peter Bou Dib, Emi Nagoshi · 2022 · Nature Communications
42. The Crucial Roles of Pitx3 in Midbrain Dopaminergic Neuron Development and Parkinson’s Disease-Associated Neurodegeneration
    Xin Wang, Xi Chen, Guangdong Liu, Huaibin Cai, Weidong Le · 2023 · International Journal of Molecular Sciences
43. Forkhead box family transcription factors as versatile regulators for cellular reprogramming to pluripotency
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44. Epigenetic Activation of the Foxa2 Gene Is Required for Maintaining the Potential of Neural Precursor Cells to Differentiate into Dopaminergic Neurons After Expansion
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45. Parkinson’s Disease: Overview of Transcription Factor Regulation, Genetics, and Cellular and Animal Models
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46. Angiopoietin-1 accelerates Alzheimer's disease via FOXA2/PEN2/APP pathway in APP/PS1 mice
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47. Nicotine-mediated effects in neuronal and mouse models of synucleinopathy
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48. Dopaminergic-Like Neurons Derived from Oral Mucosa Stem Cells by Developmental Cues Improve Symptoms in the Hemi-Parkinsonian Rat Model
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49. Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells
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50. The hTH-GFP Reporter Rat Model for the Study of Parkinson's Disease
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51. The translational potential of human induced pluripotent stem cells for clinical neurology
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52. From 2D to 3D: Development of Monolayer Dopaminergic Neuronal and Midbrain Organoid Cultures for Parkinson’s Disease Modeling and Regenerative Therapy
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53. Nato3 Integrates with the Shh-Foxa2 Transcriptional Network Regulating the Differentiation of Midbrain Dopaminergic Neurons
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54. Ageing alters the lipid sensing process in the hypothalamus of Wistar rats. Effect of food restriction
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55. Characterization and criteria of embryonic stem and induced pluripotent stem cells for a dopamine replacement therapy
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56. Injury-stimulated Sonic hedgehog expression in microglia contributes to neuroinflammatory response in the MPTP model of Parkinson's disease
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57. Versatility of Cooperative Transcriptional Activation: A Thermodynamical Modeling Analysis for Greater-Than-Additive and Less-Than-Additive Effects
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58. Neural Induction with a Dopaminergic Phenotype from Human Pluripotent Stem Cells Through a Feeder-Free Floating Aggregation Culture
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59. mRNA Transcriptomics of Galectins Unveils Heterogeneous Organization in Mouse and Human Brain
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60. Developmental pathways linked to the vulnerability of adult midbrain dopaminergic neurons to neurodegeneration
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61. Cellular Programming and Reprogramming: Sculpting Cell Fate for the Production of Dopamine Neurons for Cell Therapy
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62. Investigating the Potential Influence of Cause of Death and Cocaine Levels on the Differential Expression of Genes Associated with Cocaine Abuse
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68. Linkage of cDNA expression profiles of mesencephalic dopaminergic neurons to a genome-wide in situ hybridization database
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70. Identification of Multiple QTLs Linked to Neuropathology in the Engrailed-1 Heterozygous Mouse Model of Parkinson’s Disease
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71. The Generation of Midbrain Dopaminergic Neurons
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74. Uncovering the role of FOXA2 in the Development of Human Serotonin Neurons
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75. The Basic Helix-Loop-Helix Gene Nato3 Drives Expression of Dopaminergic Neuron Transcription Factors in Neural Progenitors
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80. Differential Expression of microRNA Profiles and Wnt Signals in Stem Cell-Derived Exosomes During Dopaminergic Neuron Differentiation
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