HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans

Chen, Di, Thomas, Emma Lynn, Kapahi, Pankaj·2009·PLoS Genetics

Cited by (250)

Items 201–250 of 250

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  4. L’homéostasie métabolique au cœur du vieillissement
    C. Terret, Florence Solari · 2012 · médecine/sciences
  5. Long‐lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolism
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  7. Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling
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  8. The signaling pathway of levamisole-sensitive-acetylcholine receptors involved in short-term forgetting of Caenorhabditis elegans
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  9. C22 disrupts embryogenesis and extends C. elegans lifespan
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  10. Antioxidant and Geroprotective Properties of the Extract of Mountain Ash (Sorbus aucuparia L.) Fruits
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  11. Oxygen and Aging
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  12. Longevity as a Complex Genetic Trait
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  13. Dietary Restriction in C. elegans
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  14. Transcriptome analyses describe the consequences of persistent HIF-1 over-activation in Caenorhabditis elegans
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  15. Genetic analysis of Caenorhabditis elegans pry-1/Axin suppressors identifies genes involved in reproductive structure development, stress responses, and aging
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    Wuhan Xiao · 2014 · Scientia Sinica Vitae
  17. HSF-1 regulates FoxO expression to induce diapause in the cotton bollworm, Helicoverpa armigera via upstream HIF-1α and MNK signaling
    Zhiren Su, Xiao-Long Su, Songshan Jiang, Wei‐Hua Xu · 2025 · Insect Biochemistry and Molecular Biology
  18. How to measure, analyze, and interpret age-related changes in Caenorhabditis elegans: Lessons for mechanistic and evolutionary theories of aging
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  19. The role of hypoxia in the regulation of serotonergic signaling: an investigation of HTR1B and TPH-1 expression in colorectal cancer and C. elegans models
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  20. Actinomyces viscosus promotes neuroprotection in C. elegans models of Parkinson’s disease
    Germain Sophie Ngana, Mercedes A. Di Bernardo, Michael Gordon Surette, Lesley T. MacNeil · 2025 · Mechanisms of Ageing and Development
  21. Ubiquitin ligases join the field of dietary restriction in C.elegans
    Mark Lucanic, Pankaj Kapahi · 2009 · Aging
  22. Stress Response Pathways
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  23. Identification of enzymes that are required for Rhodoquinone-dependent metabolism as targets for new species-specific inhibitors
    Margot J. Lautens, June H. Tan, Xènia Serrat, Samantha Del Borrello, Michael R Schertzberg, Andrew G. Fraser · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  24. Age-related decline of the unfolded protein response in the heart promotes protein misfolding and cardiac pathology
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  25. Acute caloric restriction acts on the plasma proteome and reveals Apolipoprotein C1 as a signal of nutritional state and metabolic disease
    Spyros I. Vernardis, Vadim Demichev, Oliver Lemke, Nana‐Maria Grüning, Christoph B. Messner, Matthew E. H. White, Maik Pietzner, Alina Peluso, Tinh‐Hai Collet, Elana Henning et al. · 2022 · Research Square
  26. Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling
    Priyanka Das, Alejandro Aballay, Jogender Singh · 2023 · eLife
  27. The role of neurosensory systems in the modulation of aging
    Guang Yang, Yi Sheng, Rui Xiao · 2021 · Elsevier eBooks
  28. Jujuboside A extends healthspan and enhances resistance of oxidative stress in Caenorhabditis elegans via the transcription factor DAF-16/FOXO3A and SKN-1/Nrf2
    Yunliang Cao, Shuangjie Ren, Xiaocong Li, Xin Xiao, Yi Xiao · 2026 · Frontiers in Pharmacology
  29. TOR: A Conserved Nutrient-Sensing Pathway that Determines Life-Span Across Species
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  30. Trinations aging symposium
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  31. The Effect of Reducing Endoplasmic Reticulum Stress by Tauroursodeoxycholic Acid on Caenorhabditis elegans Lifespan
    Abdullah Olgun, Zeynep Köksal, Taha Abdulkadir Çoban · 2010 · DergiPark (Istanbul University)
  32. New insights into cell non-autonomous mechanisms of theC. eleganshypoxic response
    Scott F. Leiser, Ryan Rossner, Matt R. Kaeberlein · 2016 · Worm
  33. Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling
    Priyanka Das, Alejandro Aballay, Jogender Singh · 2024 · eLife
  34. An investigation of roles for SIRT1 and dietary polyphenols in modulating the ageing process through DNA methylation
    Laura Jane Ions · 2011 · OpenGrey (Institut de l'Information Scientifique et Technique)
  35. Hypoxia-inducible regulatory networks and their roles in aging in C. elegans
    Yi Zhang · 2009 · Iowa State University Digital Repository (Iowa State University)
  36. Characterization of Carbonic Anhydrases in Models of Neuronal Differentiation and in the Nematode Caenorhabditis elegans
    Monica Vitale · 2013 · Università degli Studi di Napoli Federico II
  37. The regulation of hypoxia-inducible factor (HIF-1) and the role of HIF-1 in C. elegans longevity
    Zhiwei Zhai · 2010 · Iowa State University Digital Repository (Iowa State University)
  38. A systems biology approach to target identification using three-dimensional multi-cellular tumour spheroids (MCTS). Regio-specific molecular dissection of gene expression, protein expression and functional activity in 3D MCTS.
    Kelly M. McMahon · 2011 · Bradford Scholars (University of Bradford)
  39. MicroRNA modulation of caenorhadbitis elegans dietary restriction and longevity
    Mehul Vora · 2011 · Rutgers University Community Repository (Rutgers University)
  40. Genetic Analysis of Development and Behavior in Hypoxia and Cellular Characterization of Anoxia Induced Meiotic Prophase Arrest in Caenorhabditis Elegans
    Brent A. Little · 2011 · University of North Texas Digital Library (University of North Texas)
  41. Calorie Restriction, Mitochondria and Longevity in Saccharomyces cerevisiae
    Craig Skinner, Su-Ju Lin · 2012 · Oxidative stress and disease
  42. Oops! EMS mistakes--they're inevitable, stressful, painful and oh-so educational. This guide helps you classify them and avoid sweating the small stuff.
    P Murphy, Mike Taigman · 1998 · PubMed
  43. Metabolismo oxidativo e estado redox tecidual dependente da função e do estado nutricional de operárias de Apis mellifera L.
    Mário Sérgio Cervoni · 2019 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  44. Transcription and Aging
    Malika Saint, Pramod C. Rath · 2020 · Springer eBooks
  45. The genetic paradigms of dietary restriction fail to extend life span in cep-1(gk138) mutant of C. elegans p53 due to possible background mutations
    Anita Goyala, Aiswarya Baruah, Arnab Mukhopadhyay · 2020 · PLoS ONE
  46. Faculty Opinions recommendation of Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity.
    Max Gassmann · 2011 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  47. The Hypoxic Response and Aging
    Scott F. Leiser, Hillary A. Miller, Matt R. Kaeberlein · 2015 · Elsevier eBooks
  48. Caenorhabditis elegans: An interesting host for aging-related studies
    Shantini Vijayabalan, Priya Madhavan · 2023 · Elsevier eBooks
  49. E3 Ubiquitin ligases molecular strategies against proteostasis defects of imperfect ageing
    Arun Upadhyay, Vibhuti Joshi, Ayeman Amanullah, Ribhav Mishra, Rahul Kumar Verma, Yogita K. Adlakha, Anil Kumar Suresh, Rohan Dhiman, Sudipta Bhattacharyya, Amit Mishra · 2026 · Ageing Research Reviews
  50. An atlas of the C. elegans starvation response reveals that transcription is necessary to initiate transcriptional silencing in quiescent primordial germ cells
    Jingxian Chen, Sharan Surya, Rojin Chitrakar, Jenna R. Valley, Marcos Francisco Perez, L. Ryan Baugh · 2026 · bioRxiv (Cold Spring Harbor Laboratory)