Foxp2 Regulates Gene Networks Implicated in Neurite Outgrowth in the Developing Brain
Vernes, Sonja C., Oliver, Peter L., Spiteri, Elizabeth, Lockstone, Helen E., Puliyadi, Rathi, Taylor, Jennifer M., Ho, Joses, Mombereau, Cedric, Brewer, Ariel, Lowy, Ernesto, Nicod, Jérôme, Groszer, Matthias, Baban, Dilair, Sahgal, Natasha, Cazier, Jean-Baptiste, Ragoussis, Jiannis, Davies, Kay E., Geschwind, Daniel H., Fisher, Simon E.·2011·PLoS Genetics
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Items 101–200 of 276
- Differential coexpression of FoxP1, FoxP2, and FoxP4 in the Zebra Finch (Taeniopygia guttata) song systemEzequiel Mendoza, Kirill Tokarev, Daniel Normen Düring, Eva Camarillo‐Retamosa, Michael Nash Weiss, Arpenik Nshdejan, Constance Scharff · 2014 · The Journal of Comparative Neurology
- The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortexTatiana Popovitchenko, K. Thompson, Barbara Viljetić, X. Jiao, D. L. Kontonyiannis, Megerditch Kiledjian, Ronald P. Hart, Mladen Roko Rašin · 2016 · Scientific Reports
- FOXP2 variation in great ape populations offers insight into the evolution of communication skillsNicky Staes, Chet C. Sherwood, Katharine M. Wright, Marc de Manuel, Elaine E. Guevara, Tomàs Marquès‐Bonet, Michael Krützen, Michael Anthony Massiah, William Donald Hopkins, John J. Ely et al. · 2017 · Scientific Reports
- International Handbook of Language AcquisitionJessica S. Horst, Torkildsen, Janne von Koss · 2019 · Routledge eBooks
- Differential Song Deficits after Lentivirus-Mediated Knockdown of FoxP1, FoxP2, or FoxP4 in Area X of Juvenile Zebra FinchesPhilipp Norton, Peggy Barschke, Constance Scharff, Ezequiel Mendoza · 2019 · Journal of Neuroscience
- The untold stories of the speech gene, the FOXP2 cancer geneMaría Jesús Herrero, Yorick Gitton · 2018 · Genes & Cancer
- Transcription factor FOXP2 is a flow‐induced regulator of collecting lymphatic vesselsMagda Nohemí Hernández-Vásquez, Maria Helena Ulvmar, Alejandra González‐Loyola, Ioannis Kritikos, Ying Sun, Liqun He, Cornelia Halin, Tatiana V. Petrova, Taija Mäkinen · 2021 · The EMBO Journal
- In-depth characterisation of a cohort of individuals with missense and loss-of-function variants disrupting FOXP2Lottie D. Morison, Elisabeth Meffert, Miriam Stampfer, Irene Steiner-Wilke, Brigitte Vollmer, Katrin Schulze, Tracy Ann Briggs, Ruth O. Braden, Adam P. Vogel, Daisy G.Y. Thompson-Lake et al. · 2022 · Journal of Medical Genetics
- Dissecting FOXP2 Oligomerization and DNA BindingKatharina Häußermann, Gavin Young, Philipp Kukura, Hendrik Dietz · 2019 · Angewandte Chemie International Edition
- MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult MouseLongfei Jia, Michael Chopp, Lei Wang, Xuerong Lu, Yi Zhang, Alexandra Szalad, Zheng Gang Zhang · 2018 · Molecular Neurobiology
- Foxp2 Regulates Identities and Projection Patterns of Thalamic Nuclei During DevelopmentHaruka Ebisu, Lena Iwai, Eriko Fujita‐Jimbo, Takashi Momoi, Hiroshi Kawasaki · 2016 · Cerebral Cortex
- Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of EspinKathy Nga-Chu Lui, Wing Yip Tam, Caiji Gao, Jian‐Dong Huang, Chi Chiu Wang, Liwen Jiang, Wing‐Ho Yung, Kin Ming Kwan · 2017 · Nature Communications
- Differential and Overlapping Pattern of Foxp1 and Foxp2 Expression in the Striatum of Adult Mouse BrainWeng Lam Fong, Hsiao‐Ying Kuo, Hsiao-Lin Wu, Shih-Yun Chen, FC Liu · 2018 · Neuroscience
- Convergence of spectrums: neuronal gene network states in autism spectrum disorderJosefa M. Sullivan, Silvia De Rubeis, Anne Schaefer · 2019 · Current Opinion in Neurobiology
- Toward the Language OscillogenomeElliot Murphy, Antonio Benítez‐Burraco · 2018 · Frontiers in Psychology
- Hippocampal transcriptional dysregulation after renal ischemia and reperfusionAn‐Hsun Chou, Chiou-Mei Lee, Chun‐Yu Chen, Jiin-Tarng Liou, Fu-Chao Liu, Ying-Ling Chen, Yuan‐Ji Day · 2014 · Brain Research
- Development of Auditory Cortex CircuitsMinzi Chang, Patrick O. Kanold · 2021 · Journal of the Association for Research in Otolaryngology
- Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish—implications for neurodevelopmental disordersTeresa Lüffe, Andrea D’Orazio, Moritz Bauer, Zoi Gioga, Victoria Schoeffler, Klaus‐Peter Lesch, Marcel Romanos, Carsten Drepper, Christina Lillesaar · 2021 · Translational Psychiatry
- The Key Regulator for Language and Speech Development, FOXP2, is a Novel Substrate for SUMOylationLeslie J. Meredith, Chiung‐Min Wang, Leticia Almeida Nascimento, Runhua Liu, Lizhong Wang, Wei‐Hsiung Yang · 2015 · Journal of Cellular Biochemistry
- DLX5/6 GABAergic Expression Affects Social Vocalization: Implications for Human EvolutionLevi, Giovanni, de Lombares, Camille, Giuliani, Cristina, Iannuzzi, Vincenzo, Aouci, Rym, Garagnani, Paolo, Franceschi, Claudio, Grimaud-Hervé, Dominique, Narboux-Nême, Nicolas · 2021 · Molecular Biology and Evolution
- Recent Advances in the Genetics of Vocal LearningMichael C. Condro, Stephanie A. White · 2014 · Comparative Cognition & Behavior Reviews
- FoxP2 directly regulates the reelin receptor VLDLR developmentally and by singingIris Adam, Ezequiel Mendoza, Ursula Kobalz, Sandra Wohlgemuth, Constance Scharff · 2016 · Molecular and Cellular Neuroscience
- The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth ArrestDuncan M. Gascoyne, Hayley Spearman, Linden Lyne, Rathi Puliyadi, Marta Perez‐Alcantara, Les A. Coulton, Simon E. Fisher, Peter Ian Croucher, Alison H. Banham · 2015 · PLoS ONE
- Insights into the Genetic Foundations of Human CommunicationSarah A. Graham, Pelagia Deriziotis, Simon E. Fisher · 2015 · Neuropsychology Review
- Multiple microRNAs regulate human FOXP2 gene expression by targeting sequences in its 3' untranslated regionLijuan Fu, Zhimin Shi, Guan‐Zheng Luo, Weihong Tu, XiuJie Wang, Zhide Fang, Xiao-Ching Li · 2014 · Molecular Brain
- CNTNAP2 is a direct FoxP2 target in vitro and in vivo in zebra finches: complex regulation by age and activityIris Adam, Ezequiel Mendoza, Ursula Kobalz, Sandra Wohlgemuth, Constance Scharff · 2017 · Genes Brain & Behavior
- Control of Huntington’s Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2Lea J. Hachigian, Vítor Carmona, Robert J. Fenster, Ruth Kulicke, Adrian M Heilbut, Annie Sittler, Luís Pereira de Almeida, Jill P. Mesirov, Fan Gao, Eric D. Kolaczyk et al. · 2017 · Cell Reports
- Transcription factor binding sites are frequently under accelerated evolution in primatesXinru Zhang, Bohao Fang, Yi-Fei Huang · 2023 · Nature Communications
- Foxp2 loss of function increases striatal direct pathway inhibition via increased GABA releaseJon-Ruben van Rhijn, Simon E. Fisher, Sonja C. Vernes, Nael Nadif Kasri · 2018 · Brain Structure and Function
- Critical Role of Klf5 in Regulating Gene Expression during Post-Eyelid Opening Maturation of Mouse CorneasDoreswamy Kenchegowda, Stephen A K Harvey, Sudha Swamynathan, Kira L. Lathrop, Shivalingappa K. Swamynathan · 2012 · PLoS ONE
- Identifying Essential Cell Types and Circuits in Autism Spectrum DisordersSusan E. Maloney, Michael A. Rieger, Joseph D. Dougherty · 2013 · International review of neurobiology
- miR‑134‑5p/Foxp2/Syn1 is involved in cognitive impairment in an early vascular dementia rat modelXin Liu, Ruilin Zhang, Zimei Wu, Wenwen Si, Zhenxing Ren, Saixia Zhang, Jianhong Zhou, Dongfeng Chen · 2019 · International Journal of Molecular Medicine
- Beyond Critical Period Learning: Striatal FoxP2 Affects the Active Maintenance of Learned Vocalizations in AdulthoodNancy F. Day, Taylor G. Hobbs, Jonathan B. Heston, Stephanie A. White · 2019 · eNeuro
- FOXP1 negatively regulates intrinsic excitability in D2 striatal projection neurons by promoting inwardly rectifying and leak potassium currentsNitin Khandelwal, Sheridan Cavalier, Volodymyr Rybalchenko, Ashwinikumar Kulkarni, Ashley G. Anderson, Geneviève Konopka, Jay R. Gibson · 2021 · Molecular Psychiatry
- A novel deep learning framework with dynamic tokenization for identifying chromatin interactions along with motif importance investigationLiangcan Li, Xin Li, Hao Wu · 2025 · Briefings in Bioinformatics
- The functions of FOXP transcription factors and their regulation by post-translational modificationsCongwen Gao, Honglin Zhu, Peng Gong, Chen Wu, Xingzhi Xu, Xuefei Zhu · 2023 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- Genetic insights into the functional elements of languageÁdám Szalontai, Katalin Csiszár · 2013 · Human Genetics
- FOXP2 expression and gray matter density in the male brains of patients with schizophreniaJulio Sanjuán, Xóchitl Helga Castro-Martínez, Gracián García‐Martí, Javier González-Fernández, Roberto Sanz‐Requena, Josep Maria Haro, J. Javier Meana, Luis Martí‐Bonmatí, Juan Nácher, Noelia Sebastiá-Ortega et al. · 2020 · Brain Imaging and Behavior
- Maternal Nicotine Exposure Alters Hippocampal Microglia Polarization and Promotes Anti-inflammatory Signaling in Juvenile Offspring in MiceLi Zhou, Xinrong Tao, Gang Pang, Min Mu, Qixian Sun, Fei Liu, Yuting Hu, Huihui Tao, Bing Li, Keyi Xu · 2021 · Frontiers in Pharmacology
- Common Genetic Variants in FOXP2 Are Not Associated with Individual Differences in Language DevelopmentKathryn L. Mueller, Jeffrey Clark Murray, Jacob J. Michaelson, Morten H. Christiansen, Sheena Reilly, J. Bruce Tomblin · 2016 · PLoS ONE
- Sociability and synapse subtype-specific defects in mice lacking SRPX2, a language-associated geneBreeanne M. Soteros, Qifei Cong, Christian R. Palmer, Gek-Ming Sia · 2018 · PLoS ONE
- The Evolutionary Biology of Human NeurodevelopmentBernard J. Crespi, Emma Leach · 2015 · Wiley eBooks
- Narrowing the Genetic Causes of Language Dysfunction in the 1q21.1 Microduplication SyndromeAntonio Benítez‐Burraco, Montserrat Barcos, Isabel Espejo-Portero, Maite Fernández-Urquiza, Raúl Torres-Ruiz, Sandra Rodríguez, Ma Salud Jiménez-Romero · 2018 · Frontiers in Pediatrics
- Dissecting the cross-trait effects of the FOXP2 GWAS hit on clinical and brain phenotypes in adults with ADHDGabriela Pessin Meyer, Bruna Santos da Silva, Cibele Edom Bandeira, Maria Eduarda Araujo Tavares, Renata Basso Cupertino, Eduarda Pereira Oliveira, Diana Müller, Djenifer B. Kappel, Stefania Pigatto Teche, Eduardo Schneider Vitola et al. · 2022 · European Archives of Psychiatry and Clinical Neuroscience
- Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disordersP. Auvinen, J. Vehviläinen, H. Marjonen, V. Modhukur, J. Sokka, E. Wallen, K. Ramo, L. Ahola, A. Salumets, T. Otonkoski et al. · 2022 · BMC Medicine
- FoxP2 protein levels regulate cell morphology changes and migration patterns in the vertebrate developing telencephalonElena Garcı́a-Calero, Arancha Botella-López, Olga Bahamonde, Ariadna Perez‐Balaguer, Salvador Martı́nez · 2015 · Brain Structure and Function
- It is an organ, it is new, but it is not a new organ. Conceptualizing language from a homological perspectiveSergio Balari, Guillermo Lorenzo · 2015 · Frontiers in Ecology and Evolution
- Transcriptional Enhancers in the FOXP2 Locus Underwent Accelerated Evolution in the Human LineageAlfredo Leandro Caporale, Catalina M Gonda, Lucía F. Franchini · 2019 · Molecular Biology and Evolution
- β‐catenin regulates FOXP2 transcriptional activity via multiple binding sitesGesa Richter, Tianshu Gui, Benjamin M. R. Bourgeois, Chintan N. Koyani, Peter Ulz, Ellen Heitzer, Dirk von Lewinski, Boudewijn M.T. Burgering, Ernst Malle, Tobias Madl · 2020 · FEBS Journal
- Axon guidance pathways served as common targets for human speech/language evolution and related disordersLei, Huimeng, Yan, Zhangming, Sun, Xiaohong, Zhang, Yue, Wang, Jianhong, Ma, Caihong, Xu, Qunyuan, Wang, Rui, Jarvis, Erich D., Sun, Zhirong · 2017 · Brain and Language
- Speech- and language-linked FOXP2 mutation targets protein motors in striatal neuronsHsiao‐Ying Kuo, Shih-Yun Chen, Rui-Chi Huang, Hiroshi Takahashi, Yen‐Hui Lee, Hao-Yu Pang, Cheng-Hsi Wu, Ann M. Graybiel, FC Liu · 2023 · Brain
- Long non-coding RNA HOXA11-AS upregulates Cyclin D2 to inhibit apoptosis and promote cell cycle progression in nephroblastoma by recruiting forkhead box P2.Shibo Zhu, Jingqi Zhang, Yanhong Cui, Xiangliang Tang, Xiaofeng Gao, Dian Li, Wei Jia · 2020 · PubMed Central
- Zebrafish foxP2 Zinc Finger Nuclease Mutant Has Normal Axon PathfindingLingyan Xing, Kazuyuki Hoshijima, David Jonah Grunwald, Esther Fujimoto, Tyler S. Quist, Jacob Sneddon, Chi-Bin Chien, Tamara J. Stevenson, Joshua L. Bonkowsky · 2012 · PLoS ONE
- miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirdsZhimin Shi, Zoe Piccus, Xiaofang Zhang, Huidi Yang, Hannah Jarrell, Yan Ding, Zhao‐Qian Teng, Ofer Tchernichovski, Xiao-Ching Li · 2018 · eLife
- Laminar specific gene expression reveals differences in postnatal laminar maturation in mouse auditory, visual, and somatosensory cortexMinzi Chang, Nobuko Suzuki, Hideki Derek Kawai · 2018 · The Journal of Comparative Neurology
- An Etiological Foxp2 Mutation Impairs Neuronal Gain in Layer VI Cortico-Thalamic Cells through Increased GABAB/GIRK SignalingMélanie Druart, Matthias Groszer, Corentin Le Magueresse · 2020 · Journal of Neuroscience
- Network analysis of microRNA and mRNA seasonal dynamics in a highly plastic sensorimotor neural circuitTracy A. Larson, Karin L. Lent, Theo K. Bammler, James W. MacDonald, William E. Wood, Melissa L. Caras, Nivretta M. Thatra, Agata Budzillo, David J. Perkel, Eliot A. Brenowitz · 2015 · BMC Genomics
- MicroRNA‑376a regulates cell proliferation and apoptosis by targeting forkhead box protein P2 in lymphomaShuna Yao, Yanyan Liu, Zhihua Yao, Yan Zhao, Haiying Wang, Yuanlin Xu, Jiuyang Zhang, Jing Li, Shujun Yang · 2018 · Oncology Letters
- Global and local connectivity differences converge with gene expression in a neurodevelopmental disorder of known genetic originBathelt, Joe, Barnes, Jessica, Raymond, F Lucy, Baker, Kate, Astle, Duncan · 2017 · Cerebral Cortex
- Language Evolution: Constraints and Opportunities From Modern GeneticsDan Dediu, Morten H. Christiansen · 2016 · Topics in Cognitive Science
- High SRPX2 protein expression predicts unfavorable clinical outcome in patients with prostate cancerMeng Zhang, Xiaoli Li, Zhirui Fan, Jing Zhao, Shuzheng Liu, Mingzhi Zhang, Huixiang Li, Mariusz Adam Goscinski, Huijie Fan, Zhenhe Suo · 2018 · OncoTargets and Therapy
- A Molecular Genetic Perspective on Speech and LanguageSimon E. Fisher · 2015 · Elsevier eBooks
- Contributions of common genetic variants to specific languages and to when a language is learnedPatrick C. M. Wong, Xin Kang, Hon‐Cheong So, Kwong Wai Choy · 2022 · Scientific Reports
- Sexual differentiation of the brain in man and animals: Of relevance to Klinefelter syndrome?Margaret M. McCarthy · 2013 · American Journal of Medical Genetics Part C Seminars in Medical Genetics
- Sequencing of five left–right cerebral asymmetry genes in a cohort of schizophrenia and schizotypal disorder patients from RussiaАnastasia Levchenko, Stepan E. Davtian, Н. Н. Петрова, Yegor B. Malashichev · 2013 · Psychiatric Genetics
- The Promoter Regions of Intellectual Disability-Associated Genes Are Uniquely Enriched in LTR Sequences of the MER41 Primate-Specific Endogenous Retrovirus: An Evolutionary Connection Between Immunity and CognitionSerge Nataf, Juan Uriagereka, Antonio Benítez‐Burraco · 2019 · Frontiers in Genetics
- GABAergic neurons maturation is regulated by a delicate networkMingxing Gao, Kaizhong Wang, Hui Zhao · 2022 · International Journal of Developmental Neuroscience
- Dynamic FoxP2 levels in male zebra finches are linked to morphology of adult-born Area X medium spiny neuronsJennifer Kosubek-Langer, Constance Scharff · 2020 · Scientific Reports
- ASD-relevant Animal Models of the Foxp Family of Transcription FactorsJ. Michael Bowers · 2012 · Autism - Open Access
- FOXP2-immunoreactive corticothalamic neurons in neocortical layers 6a and 6b are tightly regulated by neuromodulatory systemsGuanxiao Qi, Danqing Yang, Fernando Messore, Arco Bast, Felipe Yáñez, Marcel Oberlaender, Dirk Feldmeyer · 2024 · iScience
- Effects of maternal bisphenol A diglycidyl ether exposure during gestation and lactation on behavior and brain development of the offspringIkuko Miyazaki, Ryo Kikuoka, Nami Isooka, Mika Takeshima, Kanau Sonobe, Rei Arai, Hidemaru Funakoshi, Kyle E. Quin, J.L. Smart, Kazumasa Zensho et al. · 2020 · Food and Chemical Toxicology
- FoxP expression identifies a Kenyon cell subtype in the honeybee mushroom bodies linking them to fruit fly αβc neuronsAdriana Schatton, Constance Scharff · 2017 · European Journal of Neuroscience
- No association between FOXP2 rs10447760 and schizophrenia in a replication study of the Chinese Han populationJiajun Yin, Ningren Jia, Yansong Liu, Chunhui Jin, Fuquan Zhang, Shui Yu, Jun Wang, Jianmin Yuan · 2018 · Psychiatric Genetics
- Sex-and Region-Dependent Expression of the Autism-Linked ADNP Correlates with Social- and Speech-Related Genes in the Canary BrainGal Hacohen-Kleiman, Stan Moaraf, Oxana Kapitansky, Illana Gozes · 2020 · Journal of Molecular Neuroscience
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- scMultiMap: Cell-type-specific mapping of enhancers and target genes from single-cell multimodal dataChang Su, Dongsoo Lee, Peng Jin, Jingfei Zhang · 2025 · Nature Communications
- Mice carrying a humanized Foxp2 knock-in allele show region-specific shifts of striatal Foxp2 expression levelsChristiane Schreiweis, Théano Irinopoulou, Beate Vieth, Lilia Laddada, Franck Oury, Eric Burguière, Wolfgang Enard, Matthias Groszer · 2019 · Cortex
- MCRIP1 promotes the expression of lung-surfactant proteins in mice by disrupting CtBP-mediated epigenetic gene silencingJane S. Weng, Takanori Nakamura, Hisashi Moriizumi, Hiroshi Takano, Ryoji Yao, Mutsuhiro Takekawa · 2019 · Communications Biology
- FOXP2 confers oncogenic effects in prostate cancerXiaoquan Zhu, Chao Chen, Wei Dong, Yong Xu, Siying Liang, Wenlong Jia, Jian Li, Yanchun Qu, Jianpo Zhai, Yaoguang Zhang et al. · 2023 · eLife
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- Dissecting FOXP2 Oligomerization and DNA BindingKatharina Häußermann, Gavin Young, Philipp Kukura, Hendrik Dietz · 2019 · Angewandte Chemie
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- Retinoic Acid Signaling: A New Piece in the Spoken Language PuzzleJon-Ruben van Rhijn, Sonja C. Vernes · 2015 · Frontiers in Psychology
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- Tubular FoxP2 and Kidney FibrosisYixin Zou, Wai Han Yiu, Sarah W.Y. Lok, Jingyuan Ma, Yuchen Feng, Kar Neng Lai, Sydney C.W. Tang · 2024 · Journal of the American Society of Nephrology
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