Ragoussis, Jiannis

Functional impact of global rare copy number variation in autism spectrum disorders

Pinto, D., Pagnamenta, A. T., Klei, L., Anney, R., Merico, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., et al. (2010) · Nature

Autism Spectrum Disorder ResearchGenomic variations and chromosomal abnormalities

Cited by 2,013

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

De Santa, F., Barozzi, I., Mietton, F., Ghisletti, S., Polletti, S., Tusi, B. K., Muller, H., Ragoussis, J., Wei, C.-L., & Natoli, G. (2010) · PLoS Biology

Genomics and Chromatin DynamicsCancer-related molecular mechanisms research

Cited by 934

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

Schödel, J., Oikonomopoulos, S., Ragoussis, J., Pugh, C. W., Ratcliffe, P. J., & Mole, D. R. (2011) · Blood

Cancer, Hypoxia, and MetabolismGenomics and Chromatin Dynamics

Cited by 724

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages

Ghisletti, S., Barozzi, I., Mietton, F., Polletti, S., De Santa, F., Venturini, E., Gregory, L., Lonie, L., Chew, A., Wei, C.-L., et al. (2010) · Immunity

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 666

QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data

Colella, S., Yau, C., Taylor, J. M., Mirza, G., Butler, H., Clouston, P., Bassett, A. S., Seller, A., Holmes, C. C., & Ragoussis, J. (2007) · Nucleic Acids Research

Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms

Cited by 616

A genome-wide scan for common alleles affecting risk for autism

Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., Sykes, N., Pagnamenta, A. T., et al. (2010) · Human Molecular Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 593

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

Mole, D. R., Blancher, C., Copley, R. R., Pollard, P. J., Gleadle, J. M., Ragoussis, J., & Ratcliffe, P. J. (2009) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismGenomics and Chromatin Dynamics

Cited by 552

Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons

Nagy, C., Maitra, M., Tanti, A., Suderman, M., Théroux, J.-F., Davoli, M. A., Perlman, K., Yerko, V., Wang, Y. C., Tripathy, S. J., et al. (2020) · Nature Neuroscience

Treatment of Major DepressionSingle-cell and spatial transcriptomics

Cited by 532

Single-nucleus RNA sequencing shows convergent evidence from different cell types for altered synaptic plasticity in major depressive disorder

Nagy, C., Maitra, M., Tanti, A., Suderman, M., Théroux, J.-F., Mechawar, N., Ragoussis, J., & Turecki, G. (2018) · Nature Neuroscience

Treatment of Major DepressionSingle-cell and spatial transcriptomics

Cited by 523

MAFG-driven astrocytes promote CNS inflammation

Wheeler, M. A., Clark, I. C., Tjon, E. C., Li, Z., Zandee, S. E. J., Couturier, C. P., Watson, B. R., Scalisi, G., Alkwai, S., Rothhammer, V., et al. (2020) · Nature

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 501

Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition

Elvidge, G. P., Glenny, L., Appelhoff, R. J., Ratcliffe, P. J., Ragoussis, J., & Gleadle, J. M. (2006) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 464

Individual common variants exert weak effects on the risk for autism spectrum disorders

Anney, R., Klei, L., Pinto, D., Almeida, J., Bacchelli, E., Baird, G., Bolshakova, N., Bölte, S., Bolton, P. F., Bourgeron, T., et al. (2012) · Human Molecular Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 375

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU

Favaro, E., Ramachandran, A., McCormick, R., Gee, H., Blancher, C., Crosby, M., Devlin, C., Blick, C., Buffa, F., Li, J.-L., et al. (2010) · PLoS ONE

Cancer, Hypoxia, and MetabolismMicroRNA in disease regulation

Cited by 324

Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain

Vernes, S. C., Oliver, P. L., Spiteri, E., Lockstone, H. E., Puliyadi, R., Taylor, J. M., Ho, J., Mombereau, C., Brewer, A., Lowy, E., et al. (2011) · PLoS Genetics

Genetics and Neurodevelopmental DisordersNeurogenesis and neuroplasticity mechanisms

Cited by 276

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder

Casey, J. P., Magalhaes, T., Conroy, J. M., Regan, R., Shah, N., Anney, R., Shields, D. C., Abrahams, B. S., Almeida, J., Bacchelli, E., et al. (2012) · Human Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 200

Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia.

Pagnamenta, A. T., Bacchelli, E., de Jonge, M. V., Mirza, G., Scerri, T. S., Minopoli, F., Chiocchetti, A., Ludwig, K. U., Hoffmann, P., Paracchini, S., et al. (2010) · Biological Psychiatry

Genomic variations and chromosomal abnormalitiesAutism Spectrum Disorder Research

Cited by 139

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

Ndila, C. M., Uyoga, S., Macharia, A. W., Nyutu, G., Peshu, N., Ojal, J., Shebe, M., Awuondo, K. O., Mturi, N., Tsofa, B., et al. (2018) · The Lancet Haematology

Malaria Research and ControlHemoglobinopathies and Related Disorders

Cited by 108

Global long non-coding RNA expression in the rostral anterior cingulate cortex of depressed suicides

Zhou, Y., Lutz, P.-E., Wang, Y. C., Ragoussis, J., & Turecki, G. (2018) · Translational Psychiatry

Cancer-related molecular mechanisms researchTreatment of Major Depression

Cited by 77

Extraction of nuclei from archived postmortem tissues for single-nucleus sequencing applications

Maitra, M., Nagy, C., Chawla, A., Wang, Y. C., Nascimento, C., Suderman, M., Théroux, J.-F., Mechawar, N., Ragoussis, J., & Turecki, G. (2021) · Nature Protocols

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 42

Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring

Kuzmin, E., Baker, T. M., Lesluyes, T., Monlong, J., Abe, K. T., Coelho, P. P., Schwartz, M., Del Corpo, J., Zou, D., Morin, G., et al. (2024) · Cell Reports

Cancer Genomics and DiagnosticsBreast Cancer Treatment Studies

Cited by 20

A distributed whole genome sequencing benchmark study

Corbett, R. D., Eveleigh, R., Whitney, J., Barai, N., Bourgey, M., Chuah, E., Johnson, J., Moore, R. A., Moradin, N., Mungall, K. L., et al. (2020) · Frontiers in Genetics

Genomics and Phylogenetic StudiesGenomics and Rare Diseases

Cited by 10

Whole-transcriptome single-cell spatial landscape of instability in human carotid atherosclerosis

Byun, J. H., Cao, Y., Harutyunyan, A. S., Oikonomopoulos, S., Ragoussis, J., Veinot, J. P., Papacostas Quintanilla, H., & Daskalopoulou, S. S. (2026) · Cardiovascular Research

Cerebrovascular and Carotid Artery DiseasesAtherosclerosis and Cardiovascular Diseases

Cited by 0