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Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature
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“participants have clearly been influenced by myths about ‘serotonin deficiency’ which are widely promoted to the general public”
From ‘In my life antidepressants have been…’: a qualitative analysis of users’ diverse experiences with antidepressants (2016) · cites this paper as [35]
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Metadata
- Authors
- Lacasse, J. R., & Leo, J.
- Affiliations
- Florida State University (US)
- Corresponding author
- Leo, Jonathan
- Venue
- PLoS Medicine
- Publisher
- Public Library of Science (PLoS)
- Published
- 2005-11-08
- Volume
- 2
- Issue
- 12
- Pages
- e392
- ISSN
- 1549-1277 (ISSN-L)
- 1549-1676
- PMC
- PMC1277931
- OpenAlex
- W1987639251
- Cited by
- 377
- References
- 35
- Citations by year
- 2026: 10 · 2025: 9 · 2024: 12 · 2023: 22 · 2022: 12 · 2021: 19 · 2020: 23 · 2019: 10 · 2018: 15 · 2017: 18 · 2016: 14 · 2015: 28 · 2014: 18 · 2013: 24 · 2012: 20
- FWCI
- 10.03
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS Medicine (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Keywords
- serotonin, depression, pharmaceutical advertising, pharmaceutical marketing, scientific evidence, selective serotonin reuptake inhibitors, antidepressants
- MeSH terms
- Advertising, Antidepressive Agents, Community Participation, Depression, Humans, Serotonin, United States, United States Food and Drug Administration, Randomized Controlled Trials as Topic, Selective Serotonin Reuptake Inhibitors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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