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PRIME: A Programme to Reduce the Treatment Gap for Mental Disorders in Five Low- and Middle-Income Countries
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CITATION: Lund, C., et al. 2012. PRIME : a programme to reduce the treatment gap for mental disorders in five low- and middle-income countries. PLoS Medicine, 9(12): 1-6, doi: 10.1371/journal.pmed.1001359.
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“Large multicountry initiatives, including the Programme for Improving Mental Health Care (PRIME) and the Emerging Mental Health Systems in LMICs (EMERALD) programme, have demonstrated the clinical feasibility and acceptability of integrating mental health into routine primary care platforms (Lund et al. 2012, Semrau et al. 2015).”
From Government-led scale-up of task-shifted mental health services in Lagos State, Nigeria: a mixed-methods descriptive-explanatory case study (2026) · cites this paper as Lund et al. 2012
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“Large multicountry initiatives such as PRIME and EMERALD illustrated that task-shifted models can achieve clinical feasibility, provider acceptability, and early service utilization gains when embedded within primary care platforms (Lund et al. 2012, Semrau et al. 2015).”
From Government-led scale-up of task-shifted mental health services in Lagos State, Nigeria: a mixed-methods descriptive-explanatory case study (2026) · cites this paper as Lund et al. 2012
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“Lund et al. used stakeholder workshops to develop their ToC and then used this to refine the substance and delivery of integrated district mental healthcare plans in five low- and middle-income countries [55].”
From Using theory of change to design and evaluate public health interventions: a systematic review (2015) · cites this paper as [55]
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“Use of robust frameworks for the design and evaluation of complex interventions: The Medical Research Council framework for complex interventions [31] is the methodological basis for the development and evaluation of multi-component packages of mental health care in PRIME.”
MethodNo health without mental health
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“In the longer term, PRIME hopes to achieve increased uptake of its research findings for mental health policy and practice in other regions of the study countries and other LMICs, and increased uptake by international development agencies and donors, to support scaling up of mental health care in LMICs and reduce the…”
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Metadata
- Authors
- Lund, C., Tomlinson, M., De Silva, M., Fekadu, A., Shidhaye, R., Jordans, M., Petersen, I., Bhana, A., Kigozi, F., Prince, M., Thornicroft, G., Hanlon, C., Kakuma, R., McDaid, D., Saxena, S., Chisholm, D., Raja, S., Kippen-Wood, S., Honikman, S., Fairall, L., & Patel, V.
- Affiliations
- University of Cape Town (ZA)
- Addis Ababa University (ET)
- Public Health Foundation of India (IN)
- London School of Hygiene & Tropical Medicine (GB)
- University of KwaZulu-Natal (ZA)
- Human Sciences Research Council (ZA)
- Makerere University (UG)
- King's College London (GB)
- The University of Melbourne (AU)
- London School of Economics and Political Science (GB)
- World Health Organization (CH)
- Corresponding author
- Lund, Crick
- ORCID
- Venue
- PLoS Medicine
- Publisher
- Public Library of Science (PLoS)
- Published
- 2012-12-27
- Volume
- 9
- Issue
- 12
- Pages
- e1001359
- ISSN
- 1549-1277 (ISSN-L)
- 1549-1676
- PMC
- PMC3531506
- OpenAlex
- W2114770054
- Cited by
- 584
- References
- 24
- Citations by year
- 2026: 20 · 2025: 29 · 2024: 27 · 2023: 52 · 2022: 39 · 2021: 65 · 2020: 91 · 2019: 63 · 2018: 46 · 2017: 39 · 2016: 37 · 2015: 47 · 2014: 21 · 2013: 8
- FWCI
- 36.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- London School of Economics and Political Science Research Online (London School of Economics and Political Science) (acceptedVersion, other-oa)
- London School of Economics and Political Science Theses Online (London School of Economics and Political Science) (acceptedVersion, other-oa)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Research Portal (King's College London) (submittedVersion, cc-by)
- Open University of Cape Town (University of Cape Town) (submittedVersion, cc-by)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, cc-by)
- SUNScholar (Stellenbosch University) (submittedVersion)
- Greater South Information System
- Funders
- World Health Organization
- South London and Maudsley NHS Foundation Trust
- Wellcome Trust
- National Institute for Health and Care Research (NF-SI-0611-10053)
- King's College London
- Department for International Development
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Surgery
- Keywords
- mental illness, treatment gap, mental health services, low- and middle-income countries, mental health policy
- MeSH terms
- Mental Disorders, Developing Countries, Ethiopia, Humans, India, Maternal Health Services, Mental Health Services, Nepal, Organizations, Nonprofit, Primary Health Care, South Africa, Uganda, Program Development, Delivery of Health Care, Integrated, Healthcare Disparities, Public-Private Sector Partnerships, Capacity Building
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