The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Stability of the wMel Wolbachia Infection following Invasion into Aedes aegypti Populations
Open accessAbstract
The wMel infection of Drosophila melanogaster was successfully transferred into Aedes aegypti mosquitoes where it has the potential to suppress dengue and other arboviruses. The infection was subsequently spread into two natural populations at Yorkeys Knob and Gordonvale near Cairns, Queensland in 2011. Here we report on the stability of the infection following introduction and we characterize factors influencing the ongoing dynamics of the infection in these two populations. While the Wolbachia infection always remained high and near fixation in both locations, there was a persistent low frequency of uninfected mosquitoes. These uninfected mosquitoes showed weak spatial structure at both release sites although there was some clustering around two areas in Gordonvale. Infected females from both locations showed perfect maternal transmission consistent with patterns previously established pre-release in laboratory tests. After >2 years under field conditions, the infection continued to show complete cytoplasmic incompatibility across multiple gonotrophic cycles but persistent deleterious fitness effects, suggesting that host effects were stable over time. These results point to the stability of Wolbachia infections and their impact on hosts following local invasion, and also highlight the continued persistence of uninfected individuals at a low frequency most likely due to immigration.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Beyond insecticides: new thinking on an ancient problem
McGraw, E. A., & O'Neill, S. L. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro2968 · Cited by 381 · cited 1×
“Wolbachia infections have been proposed as a novel intervention for the long term to suppress dengue and other arboviruses in endemic areas [9,10].”
BackgroundSelf-citation
Cited by
Establishment of Wolbachia Strain wAlbB in Malaysian Populations of Aedes aegypti for Dengue Control
Nazni, W. A., Hoffmann, A. A., NoorAfizah, A., Cheong, Y. L., Mancini, M. V., Golding, N., Kamarul, G. M. R., Arif, M. A. K., Thohir, H., NurSyamimi, H., et al. (2019) · Current Biology · doi:10.1016/j.cub.2019.11.007 · Cited by 389
Self-citationMolecular Insight into Dengue Virus Pathogenesis and Its Implications for Disease Control
Diamond, M. S., & Pierson, T. C. (2015) · Cell · doi:10.1016/j.cell.2015.07.005 · Cited by 311
O'Neill, S. L., Ryan, P. A., Turley, A. P., Wilson, G., Retzki, K., Iturbe-Ormaetxe, I., Dong, Y., Kenny, N., Paton, C. J., Ritchie, S. A., et al. (2019) · Gates Open Research · doi:10.12688/gatesopenres.12844.3 · Cited by 293
Self-citationWolbachia Infections in Aedes aegypti Differ Markedly in Their Response to Cyclical Heat Stress
Ross, P. A., Wiwatanaratanabutr, I., Axford, J. K., White, V. L., Endersby-Harshman, N. M., & Hoffmann, A. A. (2017) · PLOS Pathogens · doi:10.1371/journal.ppat.1006006 · Cited by 283
Self-citationCaragata, E. P., Pais, F. S., Baton, L. A., Silva, J. B. L., Sorgine, M. H. F., & Moreira, L. A. (2017) · BMC Genomics · doi:10.1186/s12864-016-3441-4 · Cited by 55
Metadata
- Authors
- Hoffmann, A. A., Iturbe-Ormaetxe, I., Callahan, A. G., Phillips, B. L., Billington, K., Axford, J. K., Montgomery, B., Turley, A. P., & O'Neill, S. L.
- Venue
- PLoS Neglected Tropical Diseases
- Publisher
- Public Library of Science (PLoS)
- Published
- 2014-09-11
- Volume
- 8
- Issue
- 9
- Pages
- e3115
- ISSN
- 1935-2727 (ISSN-L)
- 1935-2735
- OpenAlex
- W1974161645
- Cited by
- 315
- References
- 1
- FWCI
- 30.17
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Stability of the wMel Wolbachia Infection following Invasion into Aedes aegypti Populations. https://app.cochat.ai/papers/10.1371/journal.pntd.0003115
- The paper
- Hoffmann, A. A., Iturbe-Ormaetxe, I., Callahan, A. G., Phillips, B. L., Billington, K., Axford, J. K., Montgomery, B., Turley, A. P., & O'Neill, S. L. (2014). Stability of the wMel Wolbachia Infection following Invasion into Aedes aegypti Populations. PLoS Neglected Tropical Diseases. https://doi.org/10.1371/journal.pntd.0003115
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
