A miRNA signature of prion induced neurodegeneration.
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miR-146a is over-expressed in brain tissue of prion-infected mice compared with age-matched controls.
“We established miR-146a over-expression in prion-infected mouse brain tissues concurrent with the onset of prion deposition and appearance of activated microglia.”
From MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State (2012) · cites this paper as [17]
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Cites
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA
Klein, M. E., Lioy, D. T., Ma, L., Impey, S., Mandel, G., & Goodman, R. H. (2007) · Nature Neuroscience · doi:10.1038/nn2010 · Cited by 444 · see citing works
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease
Höglinger, G. U., Breunig, J. J., Depboylu, C., Rouaux, C., Michel, P. P., Alvarez-Fischer, D., Boutillier, A.-L., DeGregori, J., Oertel, W. H., Rakic, P., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611671104 · Cited by 276 · see citing works
Uchida, S., Nishida, A., Hara, K., Kamemoto, T., Suetsugi, M., Fujimoto, M., Watanuki, T., Wakabayashi, Y., Otsuki, K., McEwen, B. S., et al. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06218.x · Cited by 203 · see citing works
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Research works printed but not linked: 54
- [1]Prusiner SB 1998 Prions. Proc Natl Acad Sci U S A 95(23) 13363 13383 9811807 PMC33918
- [2]Riemer C Queck I Simon D Kurth R Baier M 2000 Identification of upregulated genes in scrapie-infected brain tissue. J Virol 74(21) 10245 10248 11024157 PMC102067
- [3]Xiang W Windl O Wunsch G Dugas M Kohlmann A 2004 Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology. J Virol 78(20) 11051 11060 15452225 PMC521804
- [4]Booth S Bowman C Baumgartner R Sorensen G Robertson C 2004 Identification of central nervous system genes involved in the host response to the scrapie agent during preclinical and clinical infection. J Gen Virol 85(Pt 11) 3459 3471 15483264
- [5]Skinner PJ Abbassi H Chesebro B Race RE Reilly C 2006 Gene expression alterations in brains of mice infected with three strains of scrapie. BMC Genomics 7 114 16700923 PMC1475852
- [6]Sawiris GP Becker KG Elliott EJ Moulden R Rohwer RG 2007 Molecular analysis of bovine spongiform encephalopathy infection by cDNA arrays. J Gen Virol 88(Pt 4) 1356 1362 17374782
- [7]Martinez T Pascual A 2007 Identification of genes differentially expressed in SH-SY5Y neuroblastoma cells exposed to the prion peptide 106–126. Eur J Neurosci 26(1) 51 59 17596192
- [8]Doh-ura K Perryman S Race R Chesebro B 1995 Identification of differentially expressed genes in scrapie-infected mouse neuroblastoma cells. Microb Pathog 18(1) 1 9 7783594
- [9]Greenwood AD Horsch M Stengel A Vorberg I Lutzny G 2005 Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells. J Mol Biol 349(3) 487 500 15896347
- [10]Baker CA Manuelidis L 2003 Unique inflammatory RNA profiles of microglia in creutzfeldt-jakob disease. Proc Natl Acad Sci U S A 100(2) 675 679 12525699 PMC141055
- [11]Baker CA Martin D Manuelidis L 2002 Microglia from creutzfeldt-jakob disease-infected brains are infectious and show specific mRNA activation profiles. J Virol 76(21) 10905 10913 12368333 PMC136595
- [12]Schultz J Schwarz A Neidhold S Burwinkel M Riemer C 2004 Role of interleukin-1 in prion disease-associated astrocyte activation. Am J Pathol 165(2) 671 678 15277240 PMC1618583
- [13]Bartel DP 2004 MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116(2) 281 297 14744438
- [14]Xiao C Calado DP Galler G Thai TH Patterson HC 2007 MiR-150 controls B cell differentiation by targeting the transcription factor c-myb. Cell 131(1) 146 159 17923094
- [15]Karres JS Hilgers V Carrera I Treisman J Cohen SM 2007 The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in drosophila. Cell 131(1) 136 145 17923093
- [16]Leung AK Calabrese JM Sharp PA 2006 Quantitative analysis of argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci U S A 103(48) 18125 18130 17116888 PMC1838717
- [17]Vasudevan S Tong Y Steitz JA 2007 Switching from repression to activation: MicroRNAs can up-regulate translation. Science 318(5858) 1931 1934 18048652
- [18]Bilen J Liu N Burnett BG Pittman RN Bonini NM 2006 MicroRNA pathways modulate polyglutamine-induced neurodegeneration. Mol Cell 24(1) 157 163 17018300
- [19]Lukiw WJ Pogue AI 2007 Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem 101(9) 1265 1269 17629564 PMC2080079
- [20]Wang WX Rajeev BW Stromberg AJ Ren N Tang G 2008 The expression of microRNA miR-107 decreases early in alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 28(5) 1213 1223 18234899 PMC2837363
- [21]Kim J Krichevsky A Grad Y Hayes GD Kosik KS 2004 Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc Natl Acad Sci U S A 101(1) 360 365 14691248 PMC314190
- [22]Schaefer A O'Carroll D Tan CL Hillman D Sugimori M 2007 Cerebellar neurodegeneration in the absence of microRNAs. J Exp Med 204(7) 1553 1558 17606634 PMC2118654
- [23]Saba R Booth SA 2006 Target labelling for the detection and profiling of microRNAs expressed in CNS tissue using microarrays. BMC Biotechnol 6 47 17164008 PMC1713234
- [24]Lewis BP Burge CB Bartel DP 2005 Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120(1) 15 20 15652477
- [25]Lim LP Lau NC Garrett-Engele P Grimson A Schelter JM 2005 Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433(7027) 769 773 15685193
- [26]John B Enright AJ Aravin A Tuschl T Sander C 2004 Human MicroRNA targets. PLoS Biol 2(11) e363 15502875 PMC521178
- [27]Krek A Grun D Poy MN Wolf R Rosenberg L 2005 Combinatorial microRNA target predictions. Nat Genet 37(5) 495 500 15806104
- [28]Grimson A Farh KK Johnston WK Garrett-Engele P Lim LP 2007 MicroRNA targeting specificity in mammals: Determinants beyond seed pairing. Mol Cell 27(1) 91 105 17612493 PMC3800283
- [29]Oddo S 2008 The ubiquitin-proteasome system in alzheimer's disease. J Cell Mol Med 12(2) 363 373 18266959 PMC3822529
- [30]Kitamoto T Doh-ura K Muramoto T Miyazono M Tateishi J 1992 The primary structure of the prion protein influences the distribution of abnormal prion protein in the central nervous system. Am J Pathol 141(2) 271 277 1353945 PMC1886604
- [31]Clinton J Forsyth C Royston MC Roberts GW 1993 Synaptic degeneration is the primary neuropathological feature in prion disease: A preliminary study. Neuroreport 4(1) 65 68 8453038
- [32]Jeffrey M Fraser JR Halliday WG Fowler N Goodsir CM 1995 Early unsuspected neuron and axon terminal loss in scrapie-infected mice revealed by morphometry and immunocytochemistry. Neuropathol Appl Neurobiol 21(1) 41 49 7770120
- [33]Jeffrey M Halliday WG Bell J Johnston AR MacLeod NK 2000 Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus. Neuropathol Appl Neurobiol 26(1) 41 54 10736066
- [34]Hellweg R Jockers-Scherubl M 1994 Neurotrophic factors in memory disorders. Life Sci 55(25–26) 2165 2169 7997075
- [35]Schindowski K Belarbi K Bretteville A Ando K Buee L 2008 Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation. Genes Brain Behav 7 Suppl 1 92 100 18184373 PMC2239302
- [36]Eletto D Russo G Passiatore G Del Valle L Giordano A 2008 Inhibition of SNAP25 expression by HIV-1 tat involves the activity of mir-128a. J Cell Physiol 216(3) 764 770 18381601 PMC2662126
- [37]Al-Shahrour F Minguez P Tarraga J Medina I Alloza E 2007 FatiGO+: A functional profiling tool for genomic data. integration of functional annotation, regulatory motifs and interaction data with microarray experiments. Nucleic Acids Res 35(Web Server issue) W91 6 17478504 PMC1933151
- [38]Mantamadiotis T Lemberger T Bleckmann SC Kern H Kretz O 2002 Disruption of CREB function in brain leads to neurodegeneration. Nat Genet 31(1) 47 54 11967539
- [40]Jordan-Sciutto KL Dragich JM Caltagarone J Hall DJ Bowser R 2000 Fetal alz-50 clone 1 (FAC1) protein interacts with the myc-associated zinc finger protein (ZF87/MAZ) and alters its transcriptional activity. Biochemistry 39(12) 3206 3215 10727212 PMC3667205
- [41]Gotz M Stoykova A Gruss P 1998 Pax6 controls radial glia differentiation in the cerebral cortex. Neuron 21(5) 1031 1044 9856459
- [42]Estivill-Torrus G Pearson H van Heyningen V Price DJ Rashbass P 2002 Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors. Development 129(2) 455 466 11807037
- [43]Quinn JC Molinek M Martynoga BS Zaki PA Faedo A 2007 Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanism. Dev Biol 302(1) 50 65 16979618 PMC2384163
- [44]Huang JC Babak T Corson TW Chua G Khan S 2007 Using expression profiling data to identify human microRNA targets. Nat Methods 4(12) 1045 1049 18026111
- [45]Liu T Papagiannakopoulos T Puskar K Qi S Santiago F 2007 Detection of a microRNA signal in an in vivo expression set of mRNAs. PLoS ONE 2(8) e804 17726534 PMC1950084
- [46]Sorensen G Medina S Parchaliuk D Phillipson C Robertson C 2008 Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes. BMC Genomics 9 114 18315872 PMC2294129
- [47]Kim J Inoue K Ishii J Vanti WB Voronov SV 2007 A MicroRNA feedback circuit in midbrain dopamine neurons. Science 317(5842) 1220 1224 17761882 PMC2782470
- [48]Cuellar TL Davis TH Nelson PT Loeb GB Harfe BD 2008 Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci U S A 105(14) 5614 5619 18385371 PMC2291142
- [51]Cheng HY Papp JW Varlamova O Dziema H Russell B 2007 microRNA modulation of circadian-clock period and entrainment. Neuron 54(5) 813 829 17553428 PMC2590749
- [52]Wu J Xie X 2006 Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression. Genome Biol 7(9) R85 17002790 PMC1794552
- [53]Vo N Klein ME Varlamova O Keller DM Yamamoto T 2005 A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A 102(45) 16426 16431 16260724 PMC1283476
- [54]Tusher VG Tibshirani R Chu G 2001 Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98(9) 5116 5121 11309499 PMC33173
- [55]Bussey KJ Kane D Sunshine M Narasimhan S Nishizuka S 2003 MatchMiner: A tool for batch navigation among gene and gene product identifiers. Genome Biol 4(4) R27 12702208 PMC154578
- [56]Robertson G Bilenky M Lin K He A Yuen W 2006 cisRED: A database system for genome-scale computational discovery of regulatory elements. Nucleic Acids Res 34(Database issue) D68 73 16381958 PMC1347438
- [57]Wingender E Chen X Hehl R Karas H Liebich I 2000 TRANSFAC: An integrated system for gene expression regulation. Nucleic Acids Res 28(1) 316 319 10592259 PMC102445
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“with risk for amyotrophic lateral sclerosis [33] and lipoprotein cholesterol levels [34], whereas members of the mir-320 miRNA family are significantly altered in sporadic AD brains [35] and associated with both neurite outgrowth [36] and neurodegeneration [37].”
Background
- Authors
- Saba, R., Goodman, C. D., Huzarewich, R. L. C. H., Robertson, C., & Booth, S. A.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2008-11-06
- Volume
- 3
- Issue
- 11
- Pages
- e3652
- ISSN
- 1932-6203
- PMC
- PMC2575400
- Cited by
- 206
- References
- 3
- Language
- en
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