The Fate of miRNA* Strand through Evolutionary Analysis: Implication for Degradation As Merely Carrier Strand or Potential Regulatory Molecule?
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The passenger strand of a miRNA is believed to be degraded and inactivated.
“while the passenger strand is believed to be degraded and inactivated [5, 6].”
From Stress Response of Glioblastoma Cells Mediated by miR-17-5p Targeting PTEN and the Passenger Strand miR-17-3p Targeting MDM2 (2012) · cites this paper as [5]
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Regulation of miRNA strand selection: follow the leader?
Meijer, H. A., Smith, E. M., & Bushell, M. (2014) · Biochemical Society Transactions · doi:10.1042/bst20140142 · Cited by 233 · see citing works
A Regulatory Role for MicroRNA 33* in Controlling Lipid Metabolism Gene Expression
Goedeke, L., Vales-Lara, F. M., Fenstermaker, M., Cirera-Salinas, D., Chamorro-Jorganes, A., Ramírez, C. M., Mattison, J. A., de Cabo, R., Suárez, Y., & Fernández-Hernando, C. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01714-12 · Cited by 140 · see citing works
Li, H., & Yang, B. B. (2012) · Oncotarget · doi:10.18632/oncotarget.810 · Cited by 117 · see citing works
- Authors
- Guo, L., & Lu, Z.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2010-06-30
- Volume
- 5
- Issue
- 6
- Pages
- e11387
- ISSN
- 1932-6203
- PMC
- PMC2894941
- Cited by
- 191
- References
- 1
- Language
- en
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