The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Characteristic Male Urine Microbiomes Associate with Asymptomatic Sexually Transmitted Infection
Open accessAbstract
BACKGROUND: The microbiome of the male urogenital tract is poorly described but it has been suggested that bacterial colonization of the male urethra might impact risk of sexually transmitted infection (STI). Previous cultivation-dependent studies showed that a variety of non-pathogenic bacteria colonize the urethra but did not thoroughly characterize these microbiomes or establish links between the compositions of urethral microbiomes and STI. METHODOLOGY/FINDINGS: Here, we used 16S rRNA PCR and sequencing to identify bacteria in urine specimens collected from men who lacked symptoms of urethral inflammation but who differed in status for STI. All of the urine samples contained multiple bacterial genera and many contained taxa that colonize the human vagina. Uncultivated bacteria associated with female genital tract pathology were abundant in specimens from men who had STI. CONCLUSIONS: Urine microbiomes from men with STI were dominated by fastidious, anaerobic and uncultivated bacteria. The same taxa were rare in STI negative individuals. Our findings suggest that the composition of male urine microbiomes is related to STI.
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Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB
DeSantis, T. Z., Hugenholtz, P., Larsen, N., Rojas, M., Brodie, E. L., Keller, K., Huber, T., Dalevi, D., Hu, P., & Andersen, G. L. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.03006-05 · Cited by 10,891
UniFrac: a New Phylogenetic Method for Comparing Microbial Communities
Lozupone, C., & Knight, R. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.12.8228-8235.2005 · Cited by 8,227
Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities
Ewing, B., & Green, P. (1998) · Genome Research · doi:10.1101/gr.8.3.186 · Cited by 5,439
Dethlefsen, L., Huse, S., Sogin, M. L., & Relman, D. A. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060280 · Cited by 2,361
Molecular Identification of Bacteria Associated with Bacterial Vaginosis
Fredricks, D. N., Fiedler, T. L., & Marrazzo, J. M. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043802 · Cited by 1,303
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The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults
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Microbial Biogeography of Public Restroom Surfaces
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Metadata
- Authors
- Nelson, D. E., Van Der Pol, B., Dong, Q., Revanna, K. V., Fan, B., Easwaran, S., Sodergren, E., Weinstock, G. M., Diao, L., & Fortenberry, J. D.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2010-11-24
- Volume
- 5
- Issue
- 11
- Pages
- e14116
- ISSN
- 1932-6203 (ISSN-L)
- OpenAlex
- W2095739805
- Cited by
- 269
- References
- 5
- FWCI
- 9.27
- Type
- journal article
- Language
- en
- Open access
- gold
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- Nelson, D. E., Van Der Pol, B., Dong, Q., Revanna, K. V., Fan, B., Easwaran, S., Sodergren, E., Weinstock, G. M., Diao, L., & Fortenberry, J. D. (2010). Characteristic Male Urine Microbiomes Associate with Asymptomatic Sexually Transmitted Infection. PLoS ONE. https://doi.org/10.1371/journal.pone.0014116
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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