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Cited by 97

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The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis.

Sylva, Marc, Li, Vivian S. W., Buffing, Anita A. A., van Es, Johan H., van den Born, Maaike, van der Velden, Saskia, Gunst, Quinn, Koolstra, Jan Harm, Moorman, Antoon F. M., Clevers, Hans, van den Hoff, Maurice J. B.·2011·PLoS ONE
DOI 10.1371/journal.pone.0022616PMC PMC3149603
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Crossref · 10.1371/journal.pone.0022616

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  • When ligand levels diminish, attenuators also diminish and receptors increase; signaling re-boot induces negative regulators, as observed for follistatin and follistatin-like, secondarily diminishing the intensity of age-elevated pathways.

    “When the levels of ligand(s) diminish, attenuators also diminish, and receptor(s) increase [62, 63]; signaling re-boot induces negative regulators, as we observed for follistatin and follistatin-like, secondarily diminishing the intensity of age-elevated pathways [64–66].”

    From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [65]

    The Introduction identifies follistatin-like 1 as a BMP inhibitor, supporting its description as a negative regulator. The paper studies developmental organogenesis; it does not show that restarting signaling induces follistatin or follistatin-like 1, or that either reduces the intensity of age-elevated pathways. The preceding ligand-and-receptor clause is attached to different citations. (LLM, conf=0.83)

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Research works printed but not linked: 45

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Metadata

Authors
Sylva, M., Li, V. S. W., Buffing, A. A. A., van Es, J. H., van den Born, M., van der Velden, S., Gunst, Q., Koolstra, J. H., Moorman, A. F. M., Clevers, H., & van den Hoff, M. J. B.
Venue
PLoS ONE
Publisher
Public Library of Science (PLoS)
Published
2011-08-03
Volume
6
Issue
8
Pages
e22616
ISSN
1932-6203
DOI
10.1371/journal.pone.0022616
PMC
PMC3149603
Cited by
97
References
2
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (unspecified)

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