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Induction of Growth Differentiation Factor 15 in Skeletal Muscle of Old Taurine Transporter Knockout Mouse

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Identification and characterization of human GDF15 knockouts

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Exercise and Metabolic Health: The Emerging Roles of Novel Exerkines

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Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome

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Weight Loss Correlates with Macrophage Inhibitory Cytokine-1 Expression and Might Influence Outcome in Patients with Advanced Esophageal Squamous Cell Carcinoma

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Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity

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Central mechanisms of emesis: A role for GDF15

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Targeting the GDF15 Signalling for Obesity Treatment: Recent Advances and Emerging Challenges

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Metabolic Messenger: growth differentiation factor 15

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First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15

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Living in a browning environment: Effects on Daphnia’s growth and fatty acid pattern

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Weight Loss Induced by Bariatric Surgery Restricts Hepatic GDF15 Expression

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Growth Differentiation Factor-15 as a Biomarker of Obese Pre-diabetes and Type 2 Diabetes Mellitus in Indian Subjects: A Case-control Study

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GDF15 plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets

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Cancer-associated muscle weakness - From triggers to molecular mechanisms

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New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6

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Glucagon augments the secretion of FGF21 and GDF15 in MASLD by indirect mechanisms

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Growth differentiation factor-15 prevents glucotoxicity and connexin-36 downregulation in pancreatic beta-cells

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Targeting both sides of the GDF15-GFRAL-RET receptor complex: A new approach to achieve body weight homeostasis

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Circulating Growth Differentiation Factor 15 Is Associated with Diabetic Neuropathy

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A study of serum growth differentiation factor 15 in Indian women with and without gestational diabetes mellitus in the third trimester of pregnancy and its association with pro-inflammatory markers and glucose metabolism

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Effect of a 6-Week Carbohydrate-Reduced High-Protein Diet on Levels of FGF21 and GDF15 in People With Type 2 Diabetes

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Interplay between Senescence and Macrophages in Diabetic Cardiomyopathy: A Review of the Potential Role of GDF-15 and Klotho

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Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice

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Role of GDF-15 in diabetic nephropathy: mechanisms, diagnosis, and therapeutic potential

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Elevated plasma GDF15 combined with FGF21 suggests mitochondrial dysfunction in a subgroup of anorexia nervosa patients

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Association between Circulating Growth Differentiation Factor 15 and Cirrhotic Primary Biliary Cholangitis

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Growth differentiation factor-15 as an emerging biomarker for identifying myositis

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Gastric GDF15 levels are regulated by age, sex, and nutritional status in rodents and humans

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Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis

Guo, R., Zhang, S., Li, A., Zhang, P., Peng, X., Lu, X., & Fan, X. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107711 · Cited by 9

The effect of bariatric surgery on the expression of Growth Differentiation Factor-15/Macrophage-Inhibitory Cytokine-1 (GDF-15/MIC-1) in rat

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The impact of cichorium intybus L. On GDF-15 level in obese diabetic albino mice as compared with metformin effect

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Relevance of GDF15 as a biomarker for clinical outcomes after bariatric surgery

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Growth differentiation factor 15 predicts physical function impairment in Spanish older adults: a real-world prospective study

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The role of GDF15 in food intake and appetitive behaviour

Cimino, I., & Coll, A. P. (2021) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2021.100299 · Cited by 8

Screening study of anti-emetics to improve GDF15-induced malaise and anorexia: Implications for emesis control

Borner, T., Doebley, S. A., Furst, C. D., Pataro, A. M., Halas, J. G., Gao, X., Choi, G. K., Ramadan, S. A., Chow, A., & Jonghe, B. C. D. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114229 · Cited by 8

Neuroendocrine Control of Body Energy Homeostasis

Affinati, A. H., & Myers, M. G. (2021) · Europe PMC (PubMed Central) · Cited by 8

Heightened levels of plasma growth differentiation factor 15 in men living with HIV

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A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model

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Pharmacological but Not Physiological Levels of GDF15 and FGF21 Regulate Body Weight and Glycemic Control in Obese Mice

Engelbeen, S., Jacobsen, J. M., Deisen, L., Parsche, E., Buch-Rasmussen, A. S., Clemmensen, C., Kuhre, R. E., Johann, K., & Kleinert, M. (2025) · The FASEB Journal · doi:10.1096/fj.202501350r · Cited by 8

GDF-15 as a Therapeutic Target of Diabetic Complications Increases the Risk of Gallstone Disease: Mendelian Randomization and Polygenic Risk Score Analysis

Yu, L., Zhou, Y., Wang, L., Zhou, X., Sun, J., Xiao, J., Xu, X., Larsson, S. C., Yuan, S., & Li, X. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.814457 · Cited by 7

Expression of Human NSAID Activated Gene 1 in Mice Leads to Altered Mammary Gland Differentiation and Impaired Lactation

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Changes in the prognostic values of modern cardiovascular biomarkers in relation to duration of diabetes mellitus

Resl, M., Vila, G., Heinzl, M. W., Luger, A., Neuhold, S., Prager, R., Wurm, R., Hülsmann, M., & Clodi, M. (2021) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2021.107990 · Cited by 7

Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer’s disease

Marshall, J. P. S., Huynh, K., Lancaster, G. I., Ng, J., Collins, J. M., Pernes, G., Liang, A., Featherby, T. J., Mellet, N. A., Drew, B. G., et al. (2024) · iScience · doi:10.1016/j.isci.2024.108800 · Cited by 8

New Horizons with Growth Differentiation Factor 15 in Oncology: From Cancer Cachexia and Tumour Immunity to Novel Therapeutic Strategies

Sugiyama, K., Starling, N., & Chau, I. (2025) · Current Oncology · doi:10.3390/curroncol32110604 · Cited by 6

NXNL1 negatively regulates osteoblast differentiation via GDF15‐induced PP2A Cα dependent manner in MC3T3‐E1 cells

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Daily GDF15 treatment has sex‐specific effects on body weight and food intake and does not enhance the effects of voluntary physical activity in mice

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Growth differentiation factor 15 (GDF-15) is a novel orexigen in fish

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GDF15 drives de novo lipogenesis and contributes to ovarian cancer metastasis

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Novel Insights into the Physiology of Nutrient Sensing and Gut-Brain Communication in Surgical and Experimental Obesity Therapy

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Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside

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Relationship of GDF15 with hepatic mitochondrial respiration is depending on the presence of fibrosis in obese individuals

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