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The Incubation Periods of Dengue Viruses
Open accessAbstract
Dengue viruses are major contributors to illness and death globally. Here we analyze the extrinsic and intrinsic incubation periods (EIP and IIP), in the mosquito and human, respectively. We identified 146 EIP observations from 8 studies and 204 IIP observations from 35 studies. These data were fitted with censored Bayesian time-to-event models. The best-fitting temperature-dependent EIP model estimated that 95% of EIPs are between 5 and 33 days at 25°C, and 2 and 15 days at 30°C, with means of 15 and 6.5 days, respectively. The mean IIP estimate was 5.9 days, with 95% expected between days 3 and 10. Differences between serotypes were not identified for either incubation period. These incubation period models should be useful in clinical diagnosis, outbreak investigation, prevention and control efforts, and mathematical modeling of dengue virus transmission.
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General methods for monitoring convergence of iterative simulations
Brooks, S. P., & Gelman, A. (1998) · Journal of Computational and Graphical Statistics · doi:10.1080/10618600.1998.10474787 · Cited by 6,045
Dengue: a continuing global threat
Guzman, M. G., Halstead, S. B., Artsob, H., Buchy, P., Farrar, J., Gubler, D. J., Hunsperger, E., Kroeger, A., Margolis, H. S., Martínez, E., et al. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2460 · Cited by 2,082
Cited by
Ebi, K. L., & Nealon, J. (2016) · Environmental Research · doi:10.1016/j.envres.2016.07.026 · Cited by 548
The Global Expansion of Dengue: How Aedes aegypti Mosquitoes Enabled the First Pandemic Arbovirus
Brady, O. J., & Hay, S. I. (2020) · Annual Review of Entomology · doi:10.1146/annurev-ento-011019-024918 · Cited by 405
Beyond insecticides: new thinking on an ancient problem
McGraw, E. A., & O'Neill, S. L. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro2968 · Cited by 381
Kucharski, A. J., Funk, S., Eggo, R. M., Mallet, H.-P., Edmunds, W. J., & Nilles, E. J. (2016) · PLOS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0004726 · Cited by 283
Johansson, M. A., Reich, N. G., Hota, A., Brownstein, J. S., & Santillana, M. (2016) · Scientific Reports · doi:10.1038/srep33707 · Cited by 120
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Metadata
- Authors
- Chan, M., & Johansson, M. A.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2012-11-30
- Volume
- 7
- Issue
- 11
- Pages
- e50972
- ISSN
- 1932-6203 (ISSN-L)
- OpenAlex
- W2015611314
- Cited by
- 673
- References
- 2
- FWCI
- 22.57
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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