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Patterning in Placental 11-B Hydroxysteroid Dehydrogenase Methylation According to Prenatal Socioeconomic Adversity
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“Finally, epigenetic modifications of the placenta have been shown to alter the functioning of genes and enzymes involved in regulating the degree to which maternal stress hormones and inflammation reach the developing fetus as a function of the maternal environment.24,25”
From Prenatal Social Determinants of Health: Narrative review of maternal environments and neonatal brain development (2024) · cites this paper as [25]
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“Among humans, prenatal exposure to severe stressors or trauma is associated with increased glucortocoid receptor methylation and poor perinatal outcomes [28,29], which may increase health risk over the life course.”
BackgroundFactors underlying variable DNA methylation in a human community cohort
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Cited by
Maternal immune activation and neuroinflammation in human neurodevelopmental disorders
Han, V. X., Patel, S., Jones, H. F., & Dale, R. C. (2021) · Nature Reviews Neurology · doi:10.1038/s41582-021-00530-8 · Cited by 683
Prenatal developmental origins of future psychopathology: mechanisms and pathways
Monk, C., Lugo-Candelas, C., & Trumpff, C. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095539 · Cited by 388
Monk, C., Feng, T., Lee, S., Krupska, I., Champagne, F. A., & Tycko, B. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.15091171 · Cited by 304
The omniscient placenta: Metabolic and epigenetic regulation of fetal programming
Nugent, B. M., & Bale, T. L. (2015) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2015.09.001 · Cited by 222
Maternal prenatal stress and infant DNA methylation: A systematic review
Sosnowski, D. W., Booth, C., York, T. P., Amstadter, A. B., & Kliewer, W. (2018) · Developmental Psychobiology · doi:10.1002/dev.21604 · Cited by 111
Fetal lung and placental methylation is associated with in utero nicotine exposure
Chhabra, D., Sharma, S., Kho, A. T., Gaedigk, R., Vyhlidal, C. A., Leeder, J. S., Morrow, J., Carey, V. J., Weiss, S. T., Tantisira, K. G., et al. (2014) · Epigenetics · doi:10.4161/15592294.2014.971593 · Cited by 102
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Self-citationAltered placental DNA methylation patterns associated with maternal smoking: current perspectives
Maccani, J. Z. J., & Maccani, M. (2015) · Advances in Genomics and Genetics · doi:10.2147/agg.s61518 · Cited by 62
Maternal smoking during pregnancy is associated with mitochondrial DNA methylation
Armstrong, D. A., Green, B. B., Blair, B. A., Guerin, D. J., Litzky, J. F., Chavan, N. R., Pearson, K. J., & Marsit, C. J. (2016) · Environmental Epigenetics · doi:10.1093/eep/dvw020 · Cited by 36
Self-citationHerzberg, M. P., & Smyser, C. D. (2024) · Pediatric Research · doi:10.1038/s41390-024-03345-7 · Cited by 22
Cohen, N. J., Lesseur, C., Cardenas, A., Ward-Caviness, C. K., Spring, A. C., Rager, J. E., Fry, R. C., & Eaves, L. A. (2025) · Epigenomics · doi:10.1080/17501911.2025.2533115 · Cited by 2
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Metadata
- Authors
- Appleton, A. A., Armstrong, D. A., Lesseur, C., Lee, J., Padbury, J. F., Lester, B. M., & Marsit, C. J.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2013-09-05
- Volume
- 8
- Issue
- 9
- Pages
- e74691
- ISSN
- 1932-6203
- Cited by
- 134
- References
- 12
- Language
- en
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