What Is the Evidence for Physical Therapy Poststroke? A Systematic Review and Meta-Analysis

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1. Invited Commentary on Comparison of Robotics, Functional Electrical Stimulation, and Motor Learning Methods for Treatment of Persistent Upper Extremity Dysfunction After Stroke: A Randomized Controlled Trial
   Gert Kwakkel, Erwin E. H. van Wegen, Carel G. M. Meskers · 2015 · Archives of Physical Medicine and Rehabilitation
2. Clinical and kinematic assessments of upper limb function in persons with post-stroke symptoms
   Gudrun M. Johansson · 2015 · DiVA at Umeå University (Umeå University)
3. Feasibility and cost description of highly intensive rehabilitation involving new technologies in patients with post-acute stroke—a trial of the Swiss RehabTech Initiative
   Corina Schuster‐Amft, Jan Kool, Jens Carsten Möller, Raoul Schweinfurther, Markus Josef Ernst, Leah Reicherzer, Carina Ziller, Martin E. Schwab, Simon Wieser, Markus Wirz et al. · 2022 · Pilot and Feasibility Studies
4. Adjunctive treatment and BoNT-A for post-stroke spasticity: Are we really focusing on the patient-centered goals?
   Alessio Baricich, Michele Bertoni, Andrea Santamato, Maurizio Osio, Giulio Gasperini, Alessandro Picelli, Franco Molteni, The Collaborative Working Group · 2023 · Frontiers in Neurology
5. Predicting the functional outcome of intensive inpatient rehabilitation after stroke: results from the RIPS Study
   Alessandro Sodero, Silvia Campagnini, Anita Paperini, Chiara Castagnoli, Ines Hochleitner, Angela Maria Politi, Donata Bardi, Benedetta Basagni, Teresa Barretta, Erika Guolo et al. · 2023 · European Journal of Physical and Rehabilitation Medicine
6. Combining robotics and functional electrical stimulation for assist-as-needed support of leg movements in stroke patients: A feasibility study
   Cindy J.H. Rikhof, Kasper Leerskov, Gerdienke B. Prange-Lasonder, Erik C. Prinsen, Erika Geraldina Spaich, Strahinja S. Dosen, Lotte N. S. Andreasen Struijk, Jaap H. Buurke, Johan S. Rietman · 2024 · Medical Engineering & Physics
7. AGREE: an upper limb motorized exoskeleton for restoring arm functions: a single-blinded randomized controlled trial
   Marta Gandolla, Beatrice Luciani, Valeria Longatelli, Peppino Tropea, Agnese Seregni, Massimo Corbo, Francesco Braghin, Alessandra Pedrocchi · 2025 · Journal of NeuroEngineering and Rehabilitation
8. An adaptive hand exoskeleton rehabilitation training system integrating virtual reality and an AI-based assessment engine
   Junshuo Cui · 2025 · Frontiers in Sports and Active Living
9. Non-pharmacological interventions for the improvement of post-stroke quality of life amongst older stroke survivors: a systematic review of systematic reviews (The SENATOR ONTOP series)
   Carrie Stewart, Selvarani Subbarayan, Pamela Paton, Elliot Gemmell, Iosief Abraha, Phyo Kyaw Myint, Denis O’Mahony, Antonio Cherubini, Alfonso José Cruz-Jentoft, Roy Louis Soiza · 2019 · European Geriatric Medicine
10. Extra upper limb practice after stroke: a feasibility study
    Emma J. Schneider, Louise Ada, Natasha Anne Lannin · 2019 · Pilot and Feasibility Studies
11. Gait pattern after electromechanically-assisted gait training with the Hybrid Assistive Limb and conventional gait training in sub-acute stroke rehabilitation—A subsample from a randomized controlled trial
    Anneli Wall, Susanne Margareta Palmcrantz, Jörgen Borg, Elena M. Gutierrez-Farewik · 2023 · Frontiers in Neurology
12. Haptic Nudging Using a Wearable Device to Promote Upper Limb Activity during Stroke Rehabilitation: Exploring Diurnal Variation, Repetition, and Duration of Effect
    Nada Signal, Sharon Olsen, Usman Rashid, Ruth McLaren, Alain Charles Vandal, Marcus King, Denise Taylor · 2023 · Behavioral Sciences
13. Home‐based functional electrical stimulation protocol for people with chronic stroke. Efficacy and usability of a single‐center cohort
    Felipe Covarrubias‐Escudero, F. Balbontín‐Miranda, B. Urzúa‐Soler, R. Ciuffardi, M. Muñoz, V. Hernández, Juan Pablo González Appelgren · 2024 · Artificial Organs
14. Pain management strategies among persons with long-term shoulder pain after stroke – a qualitative study
    Ingrid Lindgren, Christina B. Brogårdh, Gunvor E. Gard · 2018 · Clinical Rehabilitation
15. Intensive rehabilitation programme for patients with subacute stroke in an inpatient rehabilitation facility: describing a protocol of a prospective cohort study
    Monique Messaggi-Sartor, Jennifer Grau‐Sánchez, Anna Guillén-Solà, Roser Boza, Josep Puig, Cathy M. Stinear, Andrea Morgado-Pérez, Esther Duarte · 2021 · BMJ Open
16. Sites of electrical stimulation used in neurology
    Evelyne Castel-Lacanal · 2015 · Annals of Physical and Rehabilitation Medicine
17. Preventing muscular contractures through routine stroke patient care
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18. The role of rehabilitation therapy in Huntington disease
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19. Centre of pressure displacements produced in sitting during virtual reality training in younger and older adults and patients who have had a stroke
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20. Body composition measures may help target fundamental nutritional nursing efforts in rehabilitating patients with acquired brain injury
    Lena Aadal, Lene Odgaard, Jørgen Feldbæk Nielsen, Henrik Højgaard Rasmussen, Mette Holst · 2021 · Nursing Open
21. Continual Long-Term Physiotherapy After Stroke: A Health Technology Assessment.
    2020 · Europe PMC (PubMed Central)
22. Systematic review: Resting state functional MRI as a biomarker for non-invasive brain stimulation in upper limb recovery post-stroke
    Mudasar Aziz, Sheharyar Sajjad Baig, Wen Hai, Ali Ali, Arshad Majid, Li Su · 2025 · Neurological Sciences
23. Effects of different rehabilitation provision systems on functional recovery in patients with subacute stroke
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24. Pulmonary function in patients with chronic stroke compared with a control group of healthy people matched by age and sex
    Ana Lista-Paz, Raija Kuisma, Jesús Luis Saleta Canosa, Raquel Sebio, Luz González Doníz · 2022 · Physiotherapy Theory and Practice
25. Effects of Therapeutic Intervention on Spatiotemporal Gait Parameters in Adults With Neurologic Disorder: Systematic Review and Meta-analysis
    Alka Bishnoi, Meghna Shankar, Rachel Lee, Yang Hu, Manuel E. Hernandez · 2022 · Archives of Physical Medicine and Rehabilitation
26. Engaging in a home-based exercise program: a mixed-methods approach to identify motivators and barriers for individuals with stroke
    Sutanuka Bhattacharjya, Isabelle Linares, Jeanne Langan, Wenyao Xu, Heamchand Subryan, Lora Anne Cavuoto · 2022 · Assistive Technology
27. Botulinum Toxin and Dynamic Splint Restore Grasping Function after Stroke: A Case Report
    Denis Moskiewicz, Małgorzata Mraz, Dagmara Chamela-Bilińska · 2023 · International Journal of Environmental Research and Public Health
28. Effect of gait training using Welwalk on gait pattern in individuals with hemiparetic stroke: a cross-sectional study
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29. Influence of Kinesitherapy on Balance Reactions in Patients with Ischemic Stroke in the Chronic Period
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30. Development and validity of an innovative test to assess guideline-consistent clinical reasoning by physical therapists in stroke rehabilitation
    Nicoline M. Otterman, M Maas, Sven K. Schiemanck, Philip Jan van der Wees, Gert Kwakkel · 2019 · Journal of Rehabilitation Medicine
31. Using UHF RFID Properties to Develop and Optimize an Upper-Limb Rehabilitation System
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32. Predictive Value of Upper Extremity Outcome Measures After Stroke—A Systematic Review and Metaregression Analysis
    Silke Wolf, Christian P Gerloff, Winifried Backhaus · 2021 · Frontiers in Neurology
33. Effectiveness of dynamic neuromuscular stabilisation for improving trunk control in hemiplegic stroke: A scoping mini review
    Raghumahanti Raghuveer, Ekta Chitkara, Parul Raj Agarwal · 2022 · Neuroscience Research Notes
34. Feasibility, safety, and efficacy of task-oriented mirrored robotic training on upper-limb functions and activities of daily living in subacute poststroke patients: a pilot study
    Youze He, Zhen-Ming Huang, Haiyin Deng, Jia Huang, Jian-Huang Wu, Jing-Song Wu · 2023 · European Journal of Physical and Rehabilitation Medicine
35. Early versus delayed VR-based hand training in persons with acute stroke
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36. Impact of virtual reality game therapy and task-specific neurodevelopmental treatment on motor recovery in survivors of stroke
    Alisha Kaur, Gandhi Karunanithi Balaji, A Sahana, Suruliraj Karthikbabu · 2020 · International Journal of Therapy and Rehabilitation
37. Acute cerebral circulatory disorders and coronavirus disease
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38. A Comparative Study on the Effect of Task Specific Training on Right Versus Left Chronic Stroke Patients
    Reem Mohammed Alwhaibi, Noha F. Mahmoud, Hoda Mohamed Zakaria, Wanees Mohamed Badawy, Mahmoud Yassin Elzanaty, Walaa M. Ragab, Maher Saad Benjadid, Nisreen Naser Al Awaji, Hager Rasmy Elserougy · 2020 · International Journal of Environmental Research and Public Health
39. Viability of using a computer tablet to monitor an upper limb home exercise program in stroke
    Tamina Levy, Maggie Killington, Natasha Anne Lannin, Maria Crotty · 2019 · Physiotherapy Theory and Practice
40. Potential of robot-assisted therapy for disabled persons with MS
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41. A reaching hand : towards an Active Therapeutic Device for the upper extremity following stroke
    T. Krabben · 2018
42. Improvement of gait and balance function in chronic post-stroke patients induced by Lower Extremity – Constraint Induced Movement Therapy : a randomized controlled clinical trial
    Elaine Menezes de Oliveira, Gabriela da Silva Matuti, Clarissa Barros de Oliveira, Simone Ferreira de Freitas, Cátia M. Kawamura, José Augusto Fernandes Lopes, Jean Faber, Ricardo Mário Arida · 2024 · Brain Injury
43. Case Report: Potential benefits of a single functional neurology intervention in athletic rehabilitation and recovery: a case study
    Jorge Rey‐Mota, Guillermo Escribano‐Colmena, Eduardo Navarro-Jiménez, Carmen Cecilia Laborde-Cárdenas, Rodrigo Alejandro Yañez Sepulveda, Vicente Javier Clemente‐Suárez · 2025 · Frontiers in Sports and Active Living
44. Is there a best approach to the rehabilitation of adult hemiplegia?
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45. Effects of game-based rehabilitation on upper limb function in adults within the first six months following stroke: protocol for a systematic review and meta-analysis
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46. Effect of Virtual Reality Training Using Leap Motion Controller on Impairments and Disability in Patients with Wrist and Hand Stiffness
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47. Feasibility of Early Physical Therapy Program In-Hospital Patients with Acute Ischemic Stroke
    Kristin Grigorova-Petrova, Daniela Lubenova, Antoaneta Dimitrova, Dimo Baldaranov, Julia Lozeva · 2014 · Open Access Macedonian Journal of Medical Sciences
48. Physical activity based on daily step-count in inpatient setting in stroke and traumatic brain injury patients in subacute stage: A cross-sectional observational study
    Brigitte Mischler, Roger Hilfiker, Margret Hund‐Georgiadis, Clare C. Maguire · 2023 · Neurorehabilitation
49. Implementing digital devices to increase mobility training for people receiving inpatient rehabilitation: protocol for a feasibility hybrid type II randomized controlled trial
    Nisha Aravind, Daniel Treacy, Sakina Chagpar, Lisa Anne Harvey, Joanne Valentina Glinsky, Catherine Sherrington, Leanne M. Hassett · 2023 · Pilot and Feasibility Studies
50. Personalised Online Upper-Limb Physiotherapy for Stroke Survivors during the Inpatient Phase: A Feasibility Study
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51. Riding waves to improve functioning: a quantitative evaluation of a Surf Week in individuals with chronic phase brain injury with six months follow-up
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52. Genetic polymorphisms and post-stroke upper limb motor improvement – A systematic review and meta-analysis
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53. The Effects of Virtual Reality Training on Post-Stroke Upper and Lower Limb Function: A Meta-Analysis
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54. A Secured Smartphone-Based Architecture for Prolonged Monitoring of Neurological Gait
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55. Effectiveness of the RAPAEL Smart Board for Upper Limb Therapy in Stroke Survivors: A Pilot Controlled Trial
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56. The effect of cerebellar transcranial direct current stimulation to improve standing balance performance early post-stroke, study protocol of a randomized controlled trial
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57. Commercial gaming devices for stroke upper limb rehabilitation: The stroke survivor experience
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58. Examining user perspective of an online learning resource for physiotherapists: A mixed methods study of the TRAIN program
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59. The rehabilitation of physical function after severely disabling stroke: a survey of UK therapist practice
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60. Exploring Patient Outcomes After Participation in an Inpatient Occupation-Based Group: A Longitudinal Observational Cohort Study
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61. Effects of Combination of Functional Electric Stimulation and Robotic Leg Movement Using Dynamic Tilt Table on Walking Characteristics in Post-Stroke Patients with Spastic Hemiplegia: A Randomized Crossover-Controlled Trial
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62. Family-delivered rehabilitation services at home: is the glass empty?
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63. Factors associated with improved walking in older people during hospital rehabilitation: secondary analysis of a randomized controlled trial
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64. Supporting impaired hand function in activities of daily living and rehabilitation
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65. The Effectiveness of Thermal Stimulation Plus Conventional Therapy for Functional Recovery After Stroke: A Systematic Review and Meta-Analysis
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66. Effects of Physiotherapy Interventions for Poststroke Fatigue: A Systematic Review
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67. Interventional effects of modified constraint-induced movement therapy on upper limb function in patients who had a stroke: systematic review and meta-analysis
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68. The effects of combining anodal transcranial direct current stimulation with robot-assisted gait training on lower limb motor function and the motor cortex regulation of stroke patients
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69. Comparing the effectiveness of bimanual and unimanual mirror therapy in unilateral neglect after stroke: A pilot study
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70. The Critical Period After Stroke Study (CPASS) Upper Extremity Treatment Protocol
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71. tDCS does not add effect to foot drop stimulator and gait training in improving clinical parameters and neuroplasticity biomarkers in chronic post-stroke: randomized controlled trial
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72. Prefrontal cortex activity of active motion, cyclic electrical muscle stimulation, assisted motion, and imagery of wrist extension in stroke using fNIRS
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73. Exoskeleton-assisted training to enhance lower limb motor recovery in subacute stroke: does timing matter? A pilot randomized trial
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74. Feasibility of a task-oriented training and muscle-strengthening programme to weight-bearing symmetry after stroke
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75. Kinematic Design of a Parallel Robot for Elbow and Wrist Rehabilitation
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76. Development and Validation of an Exercise Programme for Recovery Balance Impairments in Poststroke Patients
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77. Physical therapists' perspectives on improving walking capacity in patients with stroke: a cross-sectional study from Saudi Arabia.
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78. ESTIMATION OF PAIN THRESHOLD FROM EEG SIGNALS OF SUBJECTS IN PHYSICAL THERAPY USING LONG-SHORT-TERM MEMORY DEEP LEARNING MODEL
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79. Comparing two identically protocolized, multicentre, randomized controlled trials on caregiver-mediated exercises poststroke: Any differences across countries?
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80. Investigating the association between inpatient stroke therapy and disability, destination on discharge, length of stay and mortality: a prospective cohort study using the Sentinel Stroke National Audit Programme
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81. Mirror therapy
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82. The muscle shortening maneuver in individuals with stroke: a consideration-of-concept randomized pilot trial
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83. Effect of Aging and Cortical Stroke on Motor Adaptation to Overground Gait-Slips: Quantifying Differences in Adaptation Rate and Adaptation Plateau
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84. Design and Test of E-Textiles for Stroke Rehabilitation
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85. The Effect on Muscle Activity of Reaching Beyond Arm's Length on a Mobile Seat: A Pilot Study for Trunk Control Training for People After Stroke
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86. Early Rehabilitation and Nursing Intervention (ERNI) Accelerates the Recovery of Patients With Ischemic Stroke
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87. Action observation with motor simulation improves reactive stepping responses following strong backward balance perturbations in healthy young individuals
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88. Therapists and patients perceptions of a mixed reality system designed to improve trunk control and upper extremity function
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89. Novel Wearable Device for Mindful Sensorimotor Training: Integrating Motor Decoding and Somatosensory Stimulation for Neurorehabilitation
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90. Immersive virtual reality enhanced reinforcement induced physical therapy (EVEREST)
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91. Activity monitors for increasing physical activity in adult stroke survivors
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92. Feasibility of a specific task-oriented training versus its combination with manual therapy on balance and mobility in people post stroke at the chronic stage: study protocol for a pilot randomised controlled trial
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93. Internet+Continuing Nursing (ICN) Program Promotes Motor Function Rehabilitation of Patients With Ischemic Stroke
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94. Early and Late Rehabilitation After stroke in Review: Definition, Classification, methods and Effectiveness
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95. Review on Augmented Reality Technology
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96. Spin of information and inconsistency between abstract and full text in RCTs investigating upper limb rehabilitation after stroke: An overview study
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97. Technology-Dependent Rehabilitation Involving Action Observation and Movement Imagery for Adults with Stroke: Can It Work? Feasibility of Self-Led Therapy for Upper Limb Rehabilitation after Stroke
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98. Supporting stroke survivors to meet their personal rehabilitation needs in community-based arm rehabilitation: development of initial programme theories to explore what may work for whom, how and under what circumstances
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99. Evaluating the Dissemination and Implementation Impact of a Rehabilitation Intervention: The Graded Repetitive Arm Supplementary Program (GRASP)
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100. Is There a New Road to Spinal Cord Injury Rehabilitation? A Case Report about the Effects of Driving a Go-Kart on Muscle Spasticity
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