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Resveratrol as a Natural Anti-Tumor Necrosis Factor-α Molecule: Implications to Dendritic Cells and Their Crosstalk with Mesenchymal Stromal Cells

Silva, Andreia M., Oliveira, Marta I., Sette, Laura, Almeida, Catarina R., Oliveira, Maria J., Barbosa, Mário A., Santos, Susana G.·2014·PLoS ONE
DOI 10.1371/journal.pone.0091406PMC PMC3948844
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  1. [1]Schildknecht A, Brauer S, Brenner C, Lahl K, Schild H, et al (2010) FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steady-state dendritic cells. Proc Natl Acad Sci U S A 107: 199– 203. 20018763 PMC2806715
  2. [2]Garbi N, Hammerling GJ, Probst HC, van den Broek M (2010) Tonic T cell signalling and T cell tolerance as opposite effects of self-recognition on dendritic cells. Curr Opin Immunol 22: 601– 608. 20880686
  3. [3]Miwa S, Nishida H, Tanzawa Y, Takata M, Takeuchi A, et al (2012) TNF-alpha and tumor lysate promote the maturation of dendritic cells for immunotherapy for advanced malignant bone and soft tissue tumors. PLoS One 7: e52926. 23300824 PMC3533902
  4. [4]Chomarat P, Dantin C, Bennett L, Banchereau J, Palucka AK (2003) TNF skews monocyte differentiation from macrophages to dendritic cells. J Immunol 171: 2262– 2269. 12928370
  5. [5]Feldmann M, Brennan FM, Foxwell BM, Taylor PC, Williams RO, et al (2005) Anti-TNF therapy: where have we got to in 2005? J Autoimmun 25 Suppl: 26–28 16260118
  6. [6]Jongbloed SL, Lebre MC, Fraser AR, Gracie JA, Sturrock RD, et al (2006) Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis. Arthritis Res Ther 8: R15. 16507115 PMC1526567
  7. [7]Hacquard-Bouder C, Chimenti MS, Giquel B, Donnadieu E, Fert I, et al (2007) Alteration of antigen-independent immunologic synapse formation between dendritic cells from HLA-B27-transgenic rats and CD4+ T cells: Selective impairment of costimulatory molecule engagement by mature HLA-B27. Arthritis Rheum 56: 1478– 1489. 17469106
  8. [8]Hacquard-Bouder C, Falgarone G, Bosquet A, Smaoui F, Monnet D, et al (2004) Defective costimulatory function is a striking feature of antigen-presenting cells in an HLA-B27-transgenic rat model of spondylarthropathy. Arthritis Rheum 50: 1624– 1635. 15146433
  9. [9]Elmali N, Baysal O, Harma A, Esenkaya I, Mizrak B (2007) Effects of resveratrol in inflammatory arthritis. Inflammation 30: 1– 6. 17115116
  10. [10]Elmali N, Esenkaya I, Harma A, Ertem K, Turkoz Y, et al (2005) Effect of resveratrol in experimental osteoarthritis in rabbits. Inflamm Res 54: 158– 162. 15883738
  11. [11]Okada Y, Oh-oka K, Nakamura Y, Ishimaru K, Matsuoka S, et al (2012) Dietary resveratrol prevents the development of food allergy in mice. PLoS One 7: e44338. 22962611 PMC3433457
  12. [12]Leiro JM, Varela M, Piazzon MC, Arranz JA, Noya M, et al (2010) The anti-inflammatory activity of the polyphenol resveratrol may be partially related to inhibition of tumour necrosis factor-alpha (TNF-alpha) pre-mRNA splicing. Mol Immunol 47: 1114– 1120. 19945165
  13. [13]Csiszar A, Smith K, Labinskyy N, Orosz Z, Rivera A, et al (2006) Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition. Am J Physiol Heart Circ Physiol 291: H1694– 1699. 16973825
  14. [14]Deng YH, Alex D, Huang HQ, Wang N, Yu N, et al (2011) Inhibition of TNF-alpha-mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4′-trimethoxystilbene. Phytother Res 25: 451– 457. 20740479
  15. [15]Lee B, Moon SK (2005) Resveratrol inhibits TNF-alpha-induced proliferation and matrix metalloproteinase expression in human vascular smooth muscle cells. J Nutr 135: 2767– 2773. 16317118
  16. [16]Svajger U, Obermajer N, Jeras M (2010) Dendritic cells treated with resveratrol during differentiation from monocytes gain substantial tolerogenic properties upon activation. Immunology 129: 525– 535. 20002210 PMC2842499
  17. [17]Singer NG, Caplan AI (2011) Mesenchymal stem cells: mechanisms of inflammation. Annu Rev Pathol 6: 457– 478. 21073342
  18. [18]Almeida CR, Vasconcelos DP, Goncalves RM, Barbosa MA (2012) Enhanced mesenchymal stromal cell recruitment via natural killer cells by incorporation of inflammatory signals in biomaterials. J R Soc Interface 9: 261– 271. 21752807 PMC3243397
  19. [19]Oliveira MI, Santos SG, Oliveira MJ, Torres AL, Barbosa MA (2012) Chitosan drives anti-inflammatory macrophage polarisation and pro-inflammatory dendritic cell stimulation. Eur Cell Mater 24: 136– 152 discussion 152–133. 22828991
  20. [20]Sallusto F, Lanzavecchia A (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. Journal of Experimental Medicine 179: 1109– 1118. 8145033 PMC2191432
  21. [21]Chapuis F, Rosenzwajg M, Yagello M, Ekman M, Biberfeld P, et al (1997) Differentiation of human dendritic cells from monocytes in vitro. European Journal of Immunology 27: 431– 441. 9045914
  22. [22]Verhasselt V, Buelens C, Willems F, De Groote D, Haeffner-Cavaillon N, et al (1997) Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. The Journal of Immunology 158: 2919– 2925. 9058830
  23. [23]Santos S, Lynch S, Campbell E, Antoniou A, Powis S (2008) Induction of HLA-B27 heavy chain homodimer formation after activation in dendritic cells. Arthritis Research & Therapy 10: R100. 18759962 PMC2575614
  24. [24]Mangi RJ, Kantor FS (1975) The multiple mixed lymphocyte reaction: variables important in the test as a measure of lymphocyte competence in man. Yale Journal of Biology and Medicine 48: 217– 228. 51541 PMC2595221
  25. [25]Scheinecker C, Machold KP, Majdic O, Höcker P, Knapp W, et al (1998) Initiation of the Autologous Mixed Lymphocyte Reaction Requires the Expression of Costimulatory Molecules B7–1 and B7–2 on Human Peripheral Blood Dendritic Cells. The Journal of Immunology 161: 3966– 3973. 9780165
  26. [26]Manna SK, Mukhopadhyay A, Aggarwal BB (2000) Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. J Immunol 164: 6509– 6519. 10843709
  27. [27]Ryu J, Ku BM, Lee YK, Jeong JY, Kang S, et al (2011) Resveratrol reduces TNF-alpha-induced U373MG human glioma cell invasion through regulating NF-kappaB activation and uPA/uPAR expression. Anticancer Res 31: 4223– 4230. 22199285
  28. [28]Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, et al (2006) Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8: 315– 317. 16923606
  29. [29]Bertelli AA, Baccalini R, Battaglia E, Falchi M, Ferrero ME (2001) Resveratrol inhibits TNF alpha-induced endothelial cell activation. Therapie 56: 613– 616. 11806302
  30. [30]Bi XL, Yang JY, Dong YX, Wang JM, Cui YH, et al (2005) Resveratrol inhibits nitric oxide and TNF-alpha production by lipopolysaccharide-activated microglia. Int Immunopharmacol 5: 185– 193. 15589480
  31. [31]Zhu J, Yong W, Wu X, Yu Y, Lv J, et al (2008) Anti-inflammatory effect of resveratrol on TNF-alpha-induced MCP-1 expression in adipocytes. Biochem Biophys Res Commun 369: 471– 477. 18291098
  32. [32]Kim GY, Cho H, Ahn SC, Oh YH, Lee CM, et al (2004) Resveratrol inhibits phenotypic and functional maturation of murine bone marrow-derived dendritic cells. Int Immunopharmacol 4: 245– 253. 14996416
  33. [33]Gu X, Creasy L, Kester A, Zeece M (1999) Capillary electrophoretic determination of resveratrol in wines. J Agric Food Chem 47: 3223– 3227. 10552635
  34. [34]Poulsen MM, Jorgensen JO, Jessen N, Richelsen B, Pedersen SB (2013) Resveratrol in metabolic health: an overview of the current evidence and perspectives. Ann N Y Acad Sci 1290: 74– 82. 23855468
  35. [35]Augustin MA, Sanguansri L, Lockett T (2013) Nano- and micro-encapsulated systems for enhancing the delivery of resveratrol. Ann N Y Acad Sci 1290: 107– 112. 23855472
  36. [36]Neves AR, Lucio M, Lima JL, Reis S (2012) Resveratrol in medicinal chemistry: a critical review of its pharmacokinetics, drug-delivery, and membrane interactions. Curr Med Chem 19: 1663– 1681. 22257059
  37. [37]Dai Z, Li Y, Quarles LD, Song T, Pan W, et al (2007) Resveratrol enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via ER-dependent ERK1/2 activation. Phytomedicine 14: 806– 814. 17689939
  38. [38]Kang OH, Jang HJ, Chae HS, Oh YC, Choi JG, et al (2009) Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: pivotal roles of NF-kappaB and MAPK. Pharmacol Res 59: 330– 337. 19416633
  39. [39]Kundu JK, Chun KS, Kim SO, Surh YJ (2004) Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets. Biofactors 21: 33– 39. 15630167
  40. [40]Kim YA, Choi BT, Lee YT, Park DI, Rhee SH, et al (2004) Resveratrol inhibits cell proliferation and induces apoptosis of human breast carcinoma MCF-7 cells. Oncol Rep 11: 441– 446. 14719081
  41. [41]Abrams MB, Dominguez C, Pernold K, Reger R, Wiesenfeld-Hallin Z, et al (2009) Multipotent mesenchymal stromal cells attenuate chronic inflammation and injury-induced sensitivity to mechanical stimuli in experimental spinal cord injury. Restor Neurol Neurosci 27: 307– 321. 19738324
  42. [42]Bouffi C, Djouad F, Mathieu M, Noel D, Jorgensen C (2009) Multipotent mesenchymal stromal cells and rheumatoid arthritis: risk or benefit? Rheumatology (Oxford) 48: 1185– 1189. 19561159
  43. [44]Spaggiari GM, Moretta L (2013) Cellular and molecular interactions of mesenchymal stem cells in innate immunity. Immunol Cell Biol 91: 27– 31. 23146943
  44. [45]Fu X, Han B, Cai S, Lei Y, Sun T, et al (2009) Migration of bone marrow-derived mesenchymal stem cells induced by tumor necrosis factor-alpha and its possible role in wound healing. Wound Repair Regen 17: 185– 191. 19320886
  45. [46]Bocker W, Docheva D, Prall WC, Egea V, Pappou E, et al (2008) IKK-2 is required for TNF-alpha-induced invasion and proliferation of human mesenchymal stem cells. J Mol Med (Berl) 86: 1183– 1192. 18600306
  46. [47]Tondreau T, Meuleman N, Stamatopoulos B, De Bruyn C, Delforge A, et al (2009) In vitro study of matrix metalloproteinase/tissue inhibitor of metalloproteinase production by mesenchymal stromal cells in response to inflammatory cytokines: the role of their migration in injured tissues. Cytotherapy 11: 559– 569. 19551542
  47. [48]Woo JH, Lim JH, Kim YH, Suh SI, Min DS, et al (2004) Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC delta signal transduction. Oncogene 23: 1845– 1853. 14661062

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Authors
Silva, A. M., Oliveira, M. I., Sette, L., Almeida, C. R., Oliveira, M. J., Barbosa, M. A., & Santos, S. G.
Venue
PLoS ONE
Publisher
Public Library of Science (PLoS)
Published
2014-03-10
Volume
9
Issue
3
Pages
e91406
ISSN
1932-6203
DOI
10.1371/journal.pone.0091406
PMC
PMC3948844
Cited by
34
References
1
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (unspecified)

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