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Establishment of a General NAFLD Scoring System for Rodent Models and Comparison to Human Liver Pathology

Liang, Wen, Menke, Aswin L., Driessen, Ann, Koek, Ger H., Lindeman, Jan H., Stoop, Reinout, Havekes, Louis M., Kleemann, Robert, van den Hoek, Anita M.·2014·PLoS ONE

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Crossref · 10.1371/journal.pone.0115922

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  • Steatosis and lobular inflammation scores were independently evaluated by a pathologist in a blinded fashion according to the rodent MASLD scoring system.

    “Steatosis and lobular inflammation scores were independently evaluated by a pathologist in a blinded fashion according to the rodent MASLD scoring system.58”

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Research works printed but not linked: 26

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  3. DG Tiniakos, 2010, Nonalcoholic fatty liver disease: Pathology and pathogenesis, Annu Rev Pathol, 5, 145, 10.1146/annurev-pathol-121808-102132 · DOI · Paper page
  4. ZM Younossi, 2008, Review article: Current management of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis, Aliment Pharmacol Ther, 28, 2, 10.1111/j.1365-2036.2008.03710.x · DOI
  5. DE Kleiner, 2005, Design and validation of a histological scoring system for nonalcoholic fatty liver disease, Hepatology, 41, 1313, 10.1002/hep.20701 · DOI · Paper page
  6. EM Brunt, 1999, Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions, Am J Gastroenterol, 94, 2467, 10.1111/j.1572-0241.1999.01377.x · DOI · Paper page
  7. AM van den Maagdenberg, 1993, Transgenic mice carrying the apolipoprotein E3-leiden gene exhibit hyperlipoproteinemia, J Biol Chem, 268, 10540, 10.1016/S0021-9258(18)82232-3 · DOI
  8. PM Nishina, 1990, Synthetic low and high fat diets for the study of atherosclerosis in the mouse, J Lipid Res, 31, 859, 10.1016/S0022-2275(20)42785-3 · DOI
  9. XC Jiang, 1992, Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. dependence on natural flanking sequences, J Clin Invest, 90, 1290, 10.1172/JCI115993 · DOI
  10. AM van den Hoek, 2014, APOE*3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome, Diabetes Obes Metab, 16, 537, 10.1111/dom.12252 · DOI
  11. M Westerterp, 2006, Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-leiden mice, Arterioscler Thromb Vasc Biol, 26, 2552, 10.1161/01.ATV.0000243925.65265.3c · DOI
  12. L Verschuren, 2009, MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease, Circ Res, 105, 99, 10.1161/CIRCRESAHA.109.199166 · DOI
  13. Munro B (1997) Statistical methods for health care research. New York: Lippincott Williams & Willkins.
  14. EM Brunt, 2010, Pathology of nonalcoholic fatty liver disease, Nat Rev Gastroenterol Hepatol, 7, 195, 10.1038/nrgastro.2010.21 · DOI · Paper page
  15. EM Brunt, 2001, Nonalcoholic steatohepatitis: Definition and pathology, Semin Liver Dis, 21, 3, 10.1055/s-2001-12925 · DOI
  16. P Bedossa, 2012, Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients, Hepatology, 56, 1751, 10.1002/hep.25889 · DOI
  17. C Lackner, 2011, Hepatocellular ballooning in nonalcoholic steatohepatitis: The pathologist's perspective, Expert Rev Gastroenterol Hepatol, 5, 223, 10.1586/egh.11.8 · DOI
  18. S Caldwell, 2010, Hepatocellular ballooning in NASH, J Hepatol, 53, 719, 10.1016/j.jhep.2010.04.031 · DOI
  19. W Liang, 2014, Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1beta-induced chronic inflammation, Lab Invest, 94, 491, 10.1038/labinvest.2014.11 · DOI
  20. DE Kleiner, 2012, Nonalcoholic fatty liver disease: Pathologic patterns and biopsy evaluation in clinical research, Semin Liver Dis, 32, 3, 10.1055/s-0032-1306421 · DOI
  21. NS Goldstein, 2005, Fibrosis heterogeneity in nonalcoholic steatohepatitis and hepatitis C virus needle core biopsy specimens, Am J Clin Pathol, 123, 382, 10.1309/EY72F1EN9XCB1KXX · DOI
  22. ZM Younossi, 1998, Nonalcoholic fatty liver disease: Assessment of variability in pathologic interpretations, Mod Pathol, 11, 560
  23. T Fukusato, 2005, Interobserver variation in the histopathological assessment of nonalcoholic steatohepatitis, Hepatol Res, 33, 122, 10.1016/j.hepres.2005.09.018 · DOI
  24. RB Merriman, 2006, Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver disease, Hepatology, 44, 874, 10.1002/hep.21346 · DOI
  25. R Vuppalanchi, 2009, Effects of liver biopsy sample length and number of readings on sampling variability in nonalcoholic fatty liver disease, Clin Gastroenterol Hepatol, 7, 481, 10.1016/j.cgh.2008.12.015 · DOI
  26. R Juluri, 2011, Generalizability of the nonalcoholic steatohepatitis clinical research network histologic scoring system for nonalcoholic fatty liver disease, J Clin Gastroenterol, 45, 55, 10.1097/MCG.0b013e3181dd1348 · DOI

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Metadata

Authors
Liang, W., Menke, A. L., Driessen, A., Koek, G. H., Lindeman, J. H., Stoop, R., Havekes, L. M., Kleemann, R., & van den Hoek, A. M.
Venue
PLoS ONE
Published
2014-12-23
Volume
9
Issue
12
Pages
e115922
ISSN
1932-6203
Cited by
577
References
2
Language
en

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