Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 simultaneously alleviate high-fat diet-induced colitis, endotoxemia, liver steatosis, and obesity in mice

In Kim, Hye; Kim, Jeon-Kyung; Kim, Jae-Young; Jang, Se-Eun; Han, Myung Joo; Kim, Dong-Hyun

doi:10.1016/j.nutres.2019.03.008

Cited by 82Probiotics and Fermented FoodsGut microbiota and healthGastrointestinal motility and disorders

Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 simultaneously alleviate high-fat diet-induced colitis, endotoxemia, liver steatosis, and obesity in mice

In Kim, Hye, Kim, Jeon-Kyung, Kim, Jae-Young, Jang, Se-Eun, Han, Myung Joo, Kim, Dong-Hyun·2019·Nutrition Research

DOI 10.1016/j.nutres.2019.03.008

Open this paper in CoChat — free account

Abstract

Long-term feeding of a high-fat diet (HFD) induces endotoxemia and gastrointestinal inflammation by disturbing gut microbiota composition and membrane permeability, resulting in the acceleration of obesity. Some probiotics exhibit anti-inflammatory effects in vitro and in vivo. Therefore, we hypothesized that anti-inflammatory probiotics could lead to the simultaneous attenuation of endotoxemia, liver steatosis, obesity, and colitis in mice with HFD-induced obesity. Herein, we examined whether Lactobacillus plantarum LC27 and/or Bifidobacterium longum LC, which significantly suppressed NF-κB activation in lipopolysaccharide- or fecal lysate-stimulated Caco-2 cells, could simultaneously alleviate liver steatosis and colitis in mice with HFD-induced obesity. Oral administration of LC27, LC67, or their (3:1) mixture (LM) reduced HFD-induced aspartate transaminase, alanine transaminase, triglyceride, total cholesterol, and lipopolysaccharide levels in the blood and liver. Their treatments also suppressed HFD-induced NF-κB activation and increased AMP-activated protein kinase (AMPK) activation and claudin-1 and occludin expression in the liver and colon. Moreover, LC27, LC67, or LM treatment reduced HFD-induced Firmicutes and Proteobacteria populations in gut microbiota and fecal lipopolysaccharide production. The hypothesis was supported by the findings that anti-inflammatory LC27 and/or LC67 simultaneously alleviated liver steatosis, obesity, and colitis by regulating NF-κB and AMPK activation through the inhibition of gut microbiota lipopolysaccharide production.

Integrity signals

Registry

Crossref · 10.1016/j.nutres.2019.03.008

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

An increase in microbial taxa with anti-inflammatory function, such as F. prausnitzii, E. rectale, E. hallii, and R. bromii, contributes to a reduction in metabolic endotoxemia.
“An increase in microbial taxa with anti-inflammatory function, such as Faecalibacterium prausnitzii (F. prausnitzii), Eubacterium rectale (E. rectale), E. hallii, and Ruminococcus bromii (R. bromii), contributes to a reduction in metabolic endotoxemia [41].”
From Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders (2022) · cites this paper as [41]

Human gut microbes associated with obesity
Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785 · see citing works
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
Cani, P. D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A. M., Delzenne, N. M., & Burcelin, R. (2008) · Diabetes · doi:10.2337/db07-1403 · Cited by 4,819 · see citing works
Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome
Turnbaugh, P. J., Bäckhed, F., Fulton, L., & Gordon, J. I. (2008) · Cell Host & Microbe · doi:10.1016/j.chom.2008.02.015 · Cited by 2,915 · see citing works
Macrophages, inflammation, and insulin resistance
Olefsky, J. M., & Glass, C. K. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135846 · Cited by 2,733 · see citing works
Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes
Esser, N., Legrand-Poels, S., Piette, J., Scheen, A. J., & Paquot, N. (2014) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2014.04.006 · Cited by 1,981 · see citing works
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
Li, Y., Xu, S., Mihaylova, M. M., Zheng, B., Hou, X., Jiang, B., Park, O., Luo, Z., Lefai, É., Shyy, J. Y.-J., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.03.009 · Cited by 1,788 · see citing works
High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway
Kim, K., Gu, W., Lee, I., Joh, E., & Kim, D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047713 · Cited by 1,184 · see citing works
Self-citation
Overview of Epidemiology and Contribution of Obesity to Cardiovascular Disease
Bastien, M., Poirier, P., Lemieux, I., & Després, J.-P. (2014) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2013.10.016 · Cited by 1,125 · see citing works
Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease
Kawano, Y., & Cohen, D. E. (2013) · Journal of Gastroenterology · doi:10.1007/s00535-013-0758-5 · Cited by 968 · see citing works
Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation
de La Serre, C. B., Ellis, C. L., Lee, J., Hartman, A. L., Rutledge, J. C., & Raybould, H. E. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00098.2010 · Cited by 949 · see citing works
Obesity, inflammation, and the gut microbiota
Cox, A. J., West, N. P., & Cripps, A. W. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(14)70134-2 · Cited by 869 · see citing works
Non-alcoholic fatty liver disease: An expanded review
Benedict, M., & Zhang, X. (2017) · World Journal of Hepatology · doi:10.4254/wjh.v9.i16.715 · Cited by 756 · see citing works
Establishment of a General NAFLD Scoring System for Rodent Models and Comparison to Human Liver Pathology
Liang, W., Menke, A. L., Driessen, A. L. C., Koek, G. H., Lindeman, J. H. N., Stoop, R., Havekes, L. M., Kleemann, R., & van den Hoek, A. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115922 · Cited by 607 · see citing works
The role of adipose tissue immune cells in obesity and low-grade inflammation
Mraz, M., & Haluzik, M. (2014) · Journal of Endocrinology · doi:10.1530/joe-14-0283 · Cited by 543 · see citing works
A high‐fat diet leads to the progression of non‐alcoholic fatty liver disease in obese rats
Carmiel-Haggai, M., Cederbaum, A. I., & Nieto, N. (2004) · The FASEB Journal · doi:10.1096/fj.04-2291fje · Cited by 319 · see citing works
Bifidobacterium pseudocatenulatum CECT 7765 Reduces Obesity-Associated Inflammation by Restoring the Lymphocyte-Macrophage Balance and Gut Microbiota Structure in High-Fat Diet-Fed Mice
Moya-Pérez, A., Neef, A., & Sanz, Y. (2015) · PLOS ONE · doi:10.1371/journal.pone.0126976 · Cited by 211 · see citing works
Obesity: Genes, brain, gut, and environment
Das, U. N. (2009) · Nutrition · doi:10.1016/j.nut.2009.09.020 · Cited by 207 · see citing works
Gastrointestinal inflammation by gut microbiota disturbance induces memory impairment in mice
Jang, S.-E., Lim, S.-M., Jeong, J.-J., Jang, H.-M., Lee, H.-J., Han, M. J., & Kim, D.-H. (2018) · Mucosal Immunology · doi:10.1038/mi.2017.49 · Cited by 190 · see citing works
Self-citation
Novel probiotics and prebiotics: road to the market
Kumar, H., Salminen, S., Verhagen, H., Rowland, I. R., Heimbach, J., Bañares, S., Young, T., Nomoto, K., & Lalonde, M. (2014) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2014.11.021 · Cited by 165 · see citing works
Probiotics as an immune modulator
KANG, H.-J., & IM, S.-H. (2015) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.61.s103 · Cited by 151 · see citing works
Lactobacillus brevis G-101 ameliorates colitis in mice by inhibiting NF-κB, MAPK and AKT pathways and by polarizing M1 macrophages to M2-like macrophages
Jang, S., Hyam, S. R., Han, M. J., Kim, S.-Y., Lee, B.-G., & Kim, D.-H. (2013) · Journal of Applied Microbiology · doi:10.1111/jam.12273 · Cited by 135 · see citing works
Self-citation
Oral administration of Lactobacillus plantarum K68 ameliorates DSS-induced ulcerative colitis in BALB/c mice via the anti-inflammatory and immunomodulatory activities
Liu, Y.-W., Su, Y., Ong, W.-K., Cheng, T.-H., & Tsai, Y.-C. (2011) · International Immunopharmacology · doi:10.1016/j.intimp.2011.09.013 · Cited by 118 · see citing works
β‐Sitosterol attenuates high‐fat diet‐induced intestinal inflammation in mice by inhibiting the binding of lipopolysaccharide to toll‐like receptor 4 in the NF‐κB pathway
Kim, K., Lee, I., Gu, W., Hyam, S. R., & Kim, D. (2014) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201300433 · Cited by 110 · see citing works
Self-citation
Lactobacillus plantarum CLP-0611 ameliorates colitis in mice by polarizing M1 to M2-like macrophages
Jang, S., Han, M. J., Kim, S., & Kim, D. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.04.021 · Cited by 105 · see citing works
Self-citation
Bifidobacterium adolescentis IM38 ameliorates high-fat diet–induced colitis in mice by inhibiting NF-κB activation and lipopolysaccharide production by gut microbiota
Lim, S.-M., & Kim, D. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.04.003 · Cited by 98 · see citing works
Self-citation
Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 mitigate alcoholic steatosis in mice by inhibiting LPS-mediated NF-κB activation through restoration of the disturbed gut microbiota
Kim, W.-G., Kim, H. I., Kwon, E. K., Han, M. J., & Kim, D. (2018) · Food & Function · doi:10.1039/c8fo00252e · Cited by 83 · see citing works
Self-citation
Sugary Kefir Strain Lactobacillus mali APS1 Ameliorated Hepatic Steatosis by Regulation of SIRT‐1/Nrf‐2 and Gut Microbiota in Rats
Chen, Y., Lin, Y., Lin, J., Yang, N., & Chen, M. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201700903 · Cited by 77 · see citing works
Shifts in Diet from High Fat to High Carbohydrate Improved Levels of Adipokines and Pro-inflammatory Cytokines in Mice Fed a High-fat Diet
Lee, I. S., Shin, G., & Choue, R. (2010) · Endocrine Journal · doi:10.1507/endocrj.k09e-046 · Cited by 70 · see citing works
Anti-obese effects of two Lactobacilli and two Bifidobacteria on ICR mice fed on a high fat diet
Li, Z., Jin, H. Z., Oh, S.-Y., & Ji, G. E. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.10.031 · Cited by 68 · see citing works
Lactobacillus rhamnosus CCFM1107 treatment ameliorates alcohol-induced liver injury in a mouse model of chronic alcohol feeding
Tian, F., Chi, F., Wang, G., Liu, X., Zhang, Q., Chen, Y. Q., Zhang, H., & Chen, W. (2015) · The Journal of Microbiology · doi:10.1007/s12275-015-5239-5 · Cited by 65 · see citing works
Lactobacillus acidophilus NS1 attenuates diet-induced obesity and fatty liver
Park, S. S., Lee, Y., Song, S., Kim, B., Kang, H., Oh, S., & Kim, E. (2018) · Journal of Endocrinology · doi:10.1530/joe-17-0592 · Cited by 62 · see citing works
Probiotics and Gastrointestinal Disease: Clinical Evidence and Basic Science
Petrof, E. O. (2009) · Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry · doi:10.2174/187152309789151977 · Cited by 53 · see citing works
Adipose tissue macrophages: the inflammatory link between obesity and cancer?
Wagner, M., Steinskog, E. S. S., & Wiig, H. (2014) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2014.991311 · Cited by 39 · see citing works
Lactobacillus brevis OK56 ameliorates high-fat diet-induced obesity in mice by inhibiting NF-κB activation and gut microbial LPS production
Kim, K., Jeong, J.-J., & Kim, D. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2014.12.045 · Cited by 39 · see citing works
Self-citation
Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women
Tokita, Y., Maejima, Y., Shimomura, K., Takenoshita, S., Ishiyama, N., Akuzawa, M., Shimomura, Y., & Nakajima, K. (2017) · Internal Medicine · doi:10.2169/internalmedicine.56.7115 · Cited by 35 · see citing works
Lactobacillus plantarum C29 Alleviates TNBS-Induced Memory Impairment in Mice
Lee, H.-J., Jeong, J.-J., Han, M. J., & Kim, D. (2018) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.1709.09042 · Cited by 30 · see citing works
Self-citation
Probiotic actions on diseases: implications for therapeutic treatments
Chiu, Y., Lin, S.-L., Tsai, J., & Lin, M. (2014) · Food & Function · doi:10.1039/c3fo60600g · Cited by 28 · see citing works
Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 simultaneously alleviate ethanol-induced gastritis and hepatic injury in mice
Kwon, E. K., Kang, G., Kim, W.-K., Han, M. J., & Kim, D. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.09.036 · Cited by 24 · see citing works
Self-citation

Flagged first, then by citations

1 of the 39 references couldn’t be matched to a known paper.

Sorted by citations

High-Fat, Western-Style Diet, Systemic Inflammation, and Gut Microbiota: A Narrative Review
Malesza, I. J., Malesza, M., Walkowiak, J., Mussin, N. M., Walkowiak, D., Aringazina, R. A., Bartkowiak-Wieczorek, J., & Mądry, E. (2021) · Cells · doi:10.3390/cells10113164 · Cited by 807 · see citing works
Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors
Fuke, N., Nagata, N., Suganuma, H., & Ota, T. (2019) · Nutrients · doi:10.3390/nu11102277 · Cited by 269 · see citing works
Bifidobacterium Longum: Protection against Inflammatory Bowel Disease
Yao, S., Zhao, Z., Wang, W., & Liu, X. (2021) · Journal of Immunology Research · doi:10.1155/2021/8030297 · Cited by 257 · see citing works
Lactobacillus and Bifidobacterium Improves Physiological Function and Cognitive Ability in Aged Mice by the Regulation of Gut Microbiota
Ni, Y., Yang, X., Zheng, L., Wang, Z., Wu, L., Jiang, J., Yang, T., Ma, L., & Fu, Z. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900603 · Cited by 255 · see citing works
Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders
Horn, J., Mayer, D. E., Chen, S., & Mayer, E. A. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01922-0 · Cited by 193 · see citing works
Role of probiotics in managing various human diseases, from oral pathology to cancer and gastrointestinal diseases
Petrariu, O.-A., Barbu, I. C., Niculescu, A.-G., Constantin, M., Grigore, G. A., Cristian, R.-E., Mihăescu, G., & Vrâncianu, C. O. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1296447 · Cited by 154 · see citing works
Sex-specific association between the gut microbiome and high-fat diet-induced metabolic disorders in mice
Peng, C., Xu, X., Li, Y., Li, X., Yang, X., Chen, H., Zhu, Y., Lü, N., & He, C. (2020) · Biology of Sex Differences · doi:10.1186/s13293-020-0281-3 · Cited by 82 · see citing works
A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1β Expression and Gut Microbiota
Yun, S.-W., Kim, J.-K., Lee, K., Oh, Y. J., Choi, H., Han, M. J., & Kim, D. (2020) · Nutrients · doi:10.3390/nu12113441 · Cited by 77 · see citing works
Self-citation
The ameliorative effect of probiotics on diet-induced lipid metabolism disorders: A review
Wang, Y., Ai, Z., Xing, X., Fan, Y., Zhang, Y., Nan, B., Li, X., Wang, Y., & Liu, J. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2132377 · Cited by 76 · see citing works
Gut microbiota and associated metabolites: key players in high-fat diet-induced chronic diseases
Du, W., Zou, Z., Ye, B., & Zhou, Y. Q. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2494703 · Cited by 78 · see citing works
Allicin‐induced host‐gut microbe interactions improves energy homeostasis
Zhang, C., He, X., Sheng, Y., Cui, Y., Xu, J., Zheng, S., Liu, J., Xu, W., Luo, Y., & Huang, K. (2020) · The FASEB Journal · doi:10.1096/fj.202001007r · Cited by 69 · see citing works
Lentinan Supplementation Protects the Gut–Liver Axis and Prevents Steatohepatitis: The Role of Gut Microbiota Involved
Yang, X., Zheng, M., Zhou, M., Zhou, L., Ge, X., Pang, N., Li, H., Li, X., Li, M., Zhang, J., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2021.803691 · Cited by 64 · see citing works
Exploring the Benefits of Probiotics in Gut Inflammation and Diarrhea—From an Antioxidant Perspective
Li, Q., Zheng, T., Ding, H., Chen, J., Li, B., Zhang, Q., Yang, S., Zhang, S., & Guan, W. (2023) · Antioxidants · doi:10.3390/antiox12071342 · Cited by 60 · see citing works
Probiotics for the treatment of ulcerative colitis: a review of experimental research from 2018 to 2022
Huang, C., Hao, W., Wang, X., Zhou, R., & Lin, Q. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1211271 · Cited by 59 · see citing works
Effect of Probiotic Supplementation on Intestinal Permeability in Overweight and Obesity: A Systematic Review of Randomized Controlled Trials and Animal Studies
DiMattia, Z. S., Damani, J. J., Syoc, E. P. V., & Rogers, C. J. (2023) · Advances in Nutrition · doi:10.1016/j.advnut.2023.100162 · Cited by 55 · see citing works
Internal connections between dietary intake and gut microbiota homeostasis in disease progression of ulcerative colitis: a review
Zeng, W., He, D., Xing, Y., Liu, J., Su, N., Zhang, C., Wang, Y., & Xing, X. (2021) · Food Science and Human Wellness · doi:10.1016/j.fshw.2021.02.016 · Cited by 53 · see citing works
Probiotics Alleviate Oxidative Stress in H2O2-Exposed Hepatocytes and t-BHP-Induced C57BL/6 Mice
Lee, J. Y., & Kang, C.-H. (2022) · Microorganisms · doi:10.3390/microorganisms10020234 · Cited by 49 · see citing works
Multifaceted Role of Microbiota‐Derived Indole‐3‐Acetic Acid in Human Diseases and Its Potential Clinical Application
Shaheen, N., Miao, J., Xia, B., Zhao, Y., & Zhao, J. (2025) · The FASEB Journal · doi:10.1096/fj.202500295r · Cited by 47 · see citing works
Prevention of High-Fat-Diet-Induced Dyslipidemia by Lactobacillus plantarum LP104 through Mediating Bile Acid Enterohepatic Axis Circulation and Intestinal Flora
Wang, Y. H. D., Xing, X., Ma, Y., Fan, Y., Zhang, Y., Nan, B., Li, X., Wang, Y., & Liu, J. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c09151 · Cited by 43 · see citing works
Propionate inhibits fat deposition via affecting feed intake and modulating gut microbiota in broilers
Li, H., Zhao, L., Liu, S., Zhang, Z., Wang, X., & Lin, H. (2020) · Poultry Science · doi:10.1016/j.psj.2020.10.009 · Cited by 43 · see citing works
A narrative review of the role of gastrointestinal dysbiosis in the pathogenesis of polycystic ovary syndrome
Parker, J., O'Brien, C., & Hawrelak, J. (2022) · Obstetrics & Gynecology Science · doi:10.5468/ogs.21185 · Cited by 42 · see citing works
Advances in the role and mechanism of lactic acid bacteria in treating obesity
Shen, Y., Zhang, L., Yang, Y., Yin, B., Ye, B., & Zhou, Y. Q. (2022) · Food Bioengineering · doi:10.1002/fbe2.12002 · Cited by 41 · see citing works
A review: Resistant starch, a promising prebiotic for obesity and weight management
Thompson, M. S., Yan, T. H., Saari, N., & Sarbini, S. R. (2022) · Food Bioscience · doi:10.1016/j.fbio.2022.101965 · Cited by 40 · see citing works
Modulatory effects of Lactiplantibacillus plantarum on chronic metabolic diseases
Tian, L., Zhao, R., Xu, X., Zhou, Z., Xu, X., Luo, D., Zhou, Z., Liu, Y., Kushmaro, A., Marks, R. S., et al. (2022) · Food Science and Human Wellness · doi:10.1016/j.fshw.2022.10.018 · Cited by 39 · see citing works
Polysaccharide from Ziyang Selenium-Enriched Green Tea Prevents Obesity and Promotes Adipose Thermogenesis via Modulating the Gut Microbiota
Li, D., Cheng, Y., Zeng, X., Li, Y., Xia, Z., Yang, X., & Ren, D. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c04193 · Cited by 38 · see citing works
Pediococcus pentosaceus PP04 improves high-fat diet-induced liver injury by the modulation of gut inflammation and intestinal microbiota in C57BL/6N mice
Wang, Y. H. D., Tian, Y., Zhang, N., Li, X., Wang, X., Wang, W., Zhang, J., Piao, C., Wang, Y., & Liu, J. (2021) · Food & Function · doi:10.1039/d1fo00857a · Cited by 37 · see citing works
The intestinal microbiota as a therapeutic target in the treatment of NAFLD and ALD
Huang, W., & Kong, D. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111235 · Cited by 35 · see citing works
Usefulness of Probiotics in the Management of NAFLD: Evidence and Involved Mechanisms of Action from Preclinical and Human Models
Arellano-García, L., Portillo, M. P., Martínez, J. A., & Milton‐Laskibar, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063167 · Cited by 34 · see citing works
Oral Probiotic Bifidobacterium Longum Supplementation Improves Metabolic Parameters and Alters the Expression of the Renin-Angiotensin System in Obese Mice Liver
Machado, A. S., Oliveira, J. R., Lelis, D. D. F., de Paula, A. M. B., Guimarães, A. L. S., Andrade, J. M. O., Brandi, I. V., & Santos, S. H. S. (2020) · Biological Research For Nursing · doi:10.1177/1099800420942942 · Cited by 33 · see citing works
The Potential Role of Gut Microbiota in the Prevention and Treatment of Lipid Metabolism Disorders
He, Y.-J., & You, C. (2020) · International Journal of Endocrinology · doi:10.1155/2020/8601796 · Cited by 33 · see citing works
Lactobacillus plantarum alleviates high-fat diet-induced obesity by altering the structure of mice intestinal microbial communities and serum metabolic profiles
Zhu, J., Liu, X., Liu, N., Zhao, R., & Wang, S. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1425764 · Cited by 30 · see citing works
Tight Junction Protein Expression-Inducing Probiotics Alleviate TNBS-Induced Cognitive Impairment with Colitis in Mice
Ma, X., Son, Y.-H., Yoo, J.-W., Joo, M.-K., & Kim, D. (2022) · Nutrients · doi:10.3390/nu14142975 · Cited by 31 · see citing works
Self-citation
Effects of cholesterol-lowering probiotics on non-alcoholic fatty liver disease in FXR gene knockout mice
Yang, M., Wang, H., Bukhari, I., Ye, Z., Huang, H., Yu, Y., Sun, X., Mi, Y., Lü, M., & Zheng, P. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1121203 · Cited by 25 · see citing works
Standardized hot water extract from the leaves of Hydrangea serrata (Thunb.) Ser. alleviates obesity via the AMPK pathway and modulation of the gut microbiota composition in high fat diet-induced obese mice
Han, H.-S., Lee, H.-H., Gil, H.-S., Chung, K., Kim, J.-K., Kim, D., Yoon, J., Chung, E. K., Lee, J. K., Yang, W. M., et al. (2021) · Food & Function · doi:10.1039/d0fo02185g · Cited by 25 · see citing works
Self-citation
Combined Amelioration of Prebiotic Resveratrol and Probiotic Bifidobacteria on Obesity and Nonalcoholic Fatty Liver Disease
Hu, D., Yang, W., Mao, P., & Cheng, M. (2020) · Nutrition and Cancer · doi:10.1080/01635581.2020.1767166 · Cited by 24 · see citing works
Lactiplantibacillus plantarum DSM20174 Attenuates the Progression of Non-Alcoholic Fatty Liver Disease by Modulating Gut Microbiota, Improving Metabolic Risk Factors, and Attenuating Adipose Inflammation
Riezu‐Boj, J. I., Barajas, M., Pérez, T., Pajares, M. J., Araña, M., Milagro, F. I., & Urtasun, R. (2022) · Nutrients · doi:10.3390/nu14245212 · Cited by 24 · see citing works
Review article: The complex interplay between diet and Escherichia coli in inflammatory bowel disease
Faqerah, N., Walker, D., & Gerasimidis, K. (2023) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17720 · Cited by 24 · see citing works
Anti‐obesity effect of Lactobacillus plantarum CQPC01 by modulating lipid metabolism in high‐fat diet‐induced C57BL/6 mice
Gan, Y., Tang, M., Tan, F., Zhou, X., Fan, L., Xie, Y., & Zhao, X. (2020) · Journal of Food Biochemistry · doi:10.1111/jfbc.13491 · Cited by 23 · see citing works
Limosilactobacillus fermentum MG4294 and Lactiplantibacillus plantarum MG5289 Ameliorates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced Mice
Lee, J. Y., An, M., Heo, H., Park, J.-Y., Lee, J., & Kang, C.-H. (2023) · Nutrients · doi:10.3390/nu15082005 · Cited by 22 · see citing works
Microbiota-Based Intervention Alleviates High-Fat Diet Consequences Through Host-Microbe Environment Remodeling
Yi, L., Li, Z., Xu, H. M., Shi, D., Huang, Y. K., Pan, H., Zhao, Y., Zhao, H., Yang, M., Wei, H., et al. (2025) · Nutrients · doi:10.3390/nu17091402 · Cited by 20 · see citing works
Regulating effect ofLactobacillus plantarumCQPC03 on lipid metabolism in high‐fat diet‐induced obesity in mice
Gan, Y., Chen, H., Zhou, X., Chu, L., Ran, W., Tan, F., & Zhao, X. (2020) · Journal of Food Biochemistry · doi:10.1111/jfbc.13495 · Cited by 18 · see citing works
Engineered Probiotic and Prebiotic Nutraceutical Supplementations in Combating Non-communicable Disorders: A Review
Kerry, R. G., Das, G., Golla, U., Rodríguez-Torres, M. D. P., Shin, H., & Patra, J. K. (2020) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201021666201013153142 · Cited by 17 · see citing works
Effects of dog ownership on the gut microbiota of elderly owners
Jiang, C., Cui, Z., Fan, P., & Du, G. (2022) · PLoS ONE · doi:10.1371/journal.pone.0278105 · Cited by 17 · see citing works
Probiotics intervention for type 2 diabetes mellitus therapy: a review from proposed mechanisms to future prospects
Li, X., Xia, Y., Song, X., Xiong, Z., Ai, L., & Wang, G. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2024.2387765 · Cited by 16 · see citing works
Combination of Treadmill Aerobic Exercise with Biﬁdobacterium longum OLP-01 Supplementation for Treatment of High-Fat Diet-Induced Obese Murine Model
Hsu, Y.-J., Chiu, C.-C., Lee, M., & Huang, W.-C. (2021) · Obesity Facts · doi:10.1159/000516865 · Cited by 15 · see citing works
Lactobacillus plantarum and Bifidobacterium longum Alleviate High-Fat Diet-Induced Obesity and Depression/Cognitive Impairment-like Behavior in Mice by Upregulating AMPK Activation and Downregulating Adipogenesis and Gut Dysbiosis
Yun, S.-W., Shin, Y.-J., Ma, X., & Kim, D. (2024) · Nutrients · doi:10.3390/nu16223810 · Cited by 14 · see citing works
Self-citation
Probiotics combined with atorvastatin administration in the treatment of hyperlipidemia: A randomized, double-blind, placebo-controlled clinical trial
Tian, Y., Wu, G. H., Zhao, X., Zhang, H., Ren, M., Song, X., Chang, H., & Jing, Z. (2024) · Medicine · doi:10.1097/md.0000000000037883 · Cited by 13 · see citing works
Lactobacillus plantarum and Bifidobacterium longum Alleviate Liver Injury and Fibrosis in Mice by Regulating NF-κB and AMPK Signaling
Lee, D.-Y., Shin, J., Shin, Y.-J., Han, S.-W., & Kim, D.-H. (2023) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2310.10006 · Cited by 12 · see citing works
Self-citation
Research advances in current drugs targeting hyperlipidemia (Review)
Zhao, H., Wang, Y., Li, Y., Cheng, R., & Chen, W. (2025) · Molecular Medicine Reports · doi:10.3892/mmr.2025.13623 · Cited by 10 · see citing works
Cheese containing probiotic Lactobacillus brevis NJ42 isolated from stingless bee honey reduces weight gain, fat accumulation, and glucose intolerance in mice
Hasali, N. H. M., Zamri, A. I., Lani, M. N., Matthews, V. B., & Mubarak, A. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e25981 · Cited by 8 · see citing works
Hepatoprotective Effect of Lactiplantibacillus plantarum DSR330 in Mice with High Fat Diet-Induced Nonalcoholic Fatty Liver Disease
Lee, N., Lee, Y., Shin, D.-S., Ra, J., Choi, Y., Ryu, B. H., Lee, J., Park, E., & Paik, H. (2023) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2310.10026 · Cited by 8 · see citing works
Fermented probiotic dairy products with buriti and orange byproducts enhance gut and bone health
da Graça, J. S., Sachinelli, L. D. S., Tobar, N., Guadagnini, D., Cabral, L., Noronha, M. F., Coutinho, L. L., Cazarin, C. B. B., Bogusz-Junior, S., Belangero, W. D., et al. (2025) · Food Research International · doi:10.1016/j.foodres.2025.117364 · Cited by 7 · see citing works
Protective mechanism of Bifidobacterium on intestinal mucosal barrier in sepsis
Zhang, K., Chang, Y.-F., Liu, Y.-F., Dai, S., & Li, J. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107785 · Cited by 6 · see citing works
Acesulfame potassium induces hepatic inflammation and fatty acids accumulation via disturbance of carnitine metabolism and gut microbiota
Shou, N., Rensing, C., Lin, Q., Xu, W., Fu, K., Yuan, X., Wu, D., Wang, F., Li, Y., & Shi, Z. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105101 · Cited by 6 · see citing works
Oligosaccharide equine feed supplement, Immulix, has minor impact on vaccine responses in mice
Henriksen, I. W., Castro-Mejía, J. L., Mentzel, C. M. J., Lindenberg, F., & Hansen, A. K. (2022) · Scientific Reports · doi:10.1038/s41598-021-04132-8 · Cited by 5 · see citing works
Tacrolimus-Associated Pure Red Cell Aplasia in a Patient With Renal Transplant
Yücel, O. K., Alemdar, M. S., Akkaya, B., Koçak, H., Süleymanlar, G., & YILMAZ, V. T. (2020) · Experimental and Clinical Transplantation · doi:10.6002/ect.2020.0290 · Cited by 4 · see citing works
Hericium erinaceus insoluble dietary fiber alleviates obesity induced by high-fat diet through regulating the metabolic pathway influenced by gut microbiota
Wang, G., Zhou, Q., Wang, B., Tan, X., Luo, P., Huang, Q., Shi, L., & Li, X. (2024) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2024.101560 · Cited by 4 · see citing works
Gut Microbiome as a Target for Anti-ageing Interventions
Dmytriv, T. R., & Lushchak, V. I. (2024) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-66768-8_14 · Cited by 3 · see citing works
Lactobacillus fermentum MCC2760 Attenuates Heated Oil‐Induced Brain Oxidative Stress and Inflammation via Modulation of NRF2 and NF‐kB in Rats
Keremane, V. R., Yashwanthkumar, M. H., Uppin, V., Halami, P. M., & Talahalli, R. R. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202400656 · Cited by 3 · see citing works
Evaluation of probiotic efficacy of indigenous yeast strain, Saccharomyces cerevisiae Y-89 isolated from a traditional fermented beverage of West Bengal, India having protective effect against DSS-induced colitis in experimental mice
Das, M., & Dam, S. (2024) · Archives of Microbiology · doi:10.1007/s00203-024-04128-8 · Cited by 2 · see citing works
LC2767 alleviates LPS-induced liver injury and fibrosis by regulating FXR expression, NF-κB activation, and gut microbiota
Lee, D. H., Jang, H., Shin, J., Shin, Y.-J., Kim, S. H., Han, S.-W., & Kim, D. (2026) · Scientific Reports · doi:10.1038/s41598-025-34675-z · Cited by 2 · see citing works
Self-citation
A synbiotic supplement reduces body fat and increases GLP-1 secretion in a pilot clinical study
Lin, C.-W., Zou, H.-B., Chen, R.-A., Li, C.-S., Lin, C.-Y., & Hsu, C.-C. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107171 · Cited by 2 · see citing works
Influence of Probiotics Over AMPK-Dependent Health Activity: A Look into Its Molecular Mechanisms
Ventura-Sobrevilla, J. M., Boone-Villa, D., Jiménez-Villarreal, J., & Nevárez‐Moorillón, G. V. (2020) · Microorganisms for sustainability · doi:10.1007/978-981-15-6795-7_9 · Cited by 2 · see citing works
Comprehensive characterization of multi-omics landscapes between gut microbial metabolites and the druggable genome in sepsis
Liu, J., Li, T., Li, X., Li, X., Zhang, P., & Zhu, P. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1597676 · Cited by 1 · see citing works
Lactobacillus gasseri LG 2361 from infant feces synergizes with Lactobacillus acidophilus ATCC 43121 to lower lipids in high-fat fed mice
Lü, X., Cheng, X., & Li, G. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.107365 · Cited by 1 · see citing works
Screening and Genetic Analysis of Bifidobacterium longum subsp. Longum dipro-X for IBD Alleviation
Hao, Y., Hu, W., Chen, W., Xu, N., Luo, J., Xiang, W., Wu, J., Jiang, W., Chen, D., & Yu, Q. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10788-9 · Cited by 1 · see citing works
Body mass index and gastrointestinal inflammation: Bio-molecular pathophysiology
Anaya‐Prado, R., Murrieta-Verduzco, A. M., Peña-Mascorro, I. R., Portillo-Valles, A. C., Calderon-Velazquez, A., Lopez-Hernandez, H., Monge-Rosales, D. G., de Oca-Martinez, J. L. M., Castellanos-Garcia, C. E., Servin-Romero, G., et al. (2026) · World Journal of Gastrointestinal Pathophysiology · doi:10.4291/wjgp.120474 · Cited by 1 · see citing works
Effect of Pre/Probiotic Supplementation on Metabolic Endotoxemia
Bansal, S., & Bansal, N. (2022) · Springer eBooks · doi:10.1007/978-981-16-8444-9_3 · Cited by 1 · see citing works
Gut Microbiota and Its Role in Human Metabolic Disorders
Yadav, A., Mohite, S. V., Behl, A., Shinde, P. B., & Sharma, K. K. (2023) · Springer eBooks · doi:10.1007/978-981-99-3126-2_14 · Cited by 1 · see citing works
Evaluation of Green Tea Yoghurt Enriched with Lacticaseibacillus paracasei E1 Microcapsules on Macrophage M1 Profile in High Fat-Fructose Diet Mice
Ardiansyah, E., Sa’adah, N. A. M., Izati, R., Faizah, B. N. A., Fadlilah, D. N., Kavitarna, S. A., Atho’illah, M. F., Arifah, S. N., Jatmiko, Y. D., & Rifa’i, M. (2025) · Karbala International Journal of Modern Science · doi:10.33640/2405-609x.3390 · Cited by 1 · see citing works
Endotoxin and metabolically associated pathology
Fadieienko, G. D., Gridnyev, O., & Gridnieva, S. V. (2020) · Modern Gastroenterology · doi:10.30978/mg-2020-4-80
Evaluation of polysaccharides from Laetiporus sulphureus on the growth of gastrointestinal probiotics and in vitro digestion
Zhu, X., Lin, S., & Wei, Q. (2024) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2024.1470426
Effect of dietary supplementation of Fructobacillus fructosus MCC 3996 on body weight, serum lipid and liver histopathology of high‑fat diet-fed swiss albino mice
Patil, M. P., Bhuktar, J., Ahire, J. J., & Patil, U. K. (2025) · The Microbe · doi:10.1016/j.microb.2025.100295
Synthesis and application of encapsulated Bifidobacterium Longum for mitigation of liver fibrosis via modulation of oxidative stress and inflammation in BDL rat model
Amiri, S., Motallebi, M., Hemmati-Dinarvand, M., Karimi, M., Taheri, M. A., Asouri, S. A., & Shahaboddin, M. E. (2026) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-026-04838-9
Lactiplantibacillus plantarum Q180 improves early HFD-induced MASLD by modulating gut–liver axis inflammation and barrier integrityPreprint
Kim, Y.-W., Joung, H., Jang, H., Lee, J., Lee, J.-W., Kwon, Y. J., Shin, C. H., Lee, J., & Ha, J. (2026) · Research Square · doi:10.21203/rs.3.rs-8716793/v1
The gut-liver axis in chronic liver diseases: An integrative immunopathological perspective bridging animal models and human evidence.
Khafaga, A., Rudayni, H., Khalifa, N. E., Alawam, A. S., Allam, A. A., Taha, A., Naiel, M., & El-Hack, M. A. A. (2026) · Tissue & Cell · doi:10.1016/j.tice.2026.103456
Bifidobacterium breve BBr60 Improves Metabolic Abnormalities by Regulating Gut Microbiota Balance in a High‐Fat Diet‐Induced Obese Mouse Model
Liao, Y., Yuan, X., Qin, A., Qi, Y., Shan, C., & Ma, J. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70972
The Role of Gut Microbiota in Osteoporosis Triggered by High-Fat Diets: Mechanisms and Targeted Therapeutic Strategies
Wang, X., Lin, L., Xiao, Y., Liu, R., Cai, Y., Liu, W., & Zhao, K. (2026) · Frontiers in Bioscience-Landmark · doi:10.31083/fbl46209
Lactiplantibacillus plantarum Q180 Mitigates Early High-Fat Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease by Modulating Gut–Liver Axis Inflammation and Barrier Integrity
Kim, Y.-W., Joung, H., Jang, H., Lee, J., Lee, J., Kwon, Y. J., Shin, C. H., Lee, J., & Ha, J. (2026) · Journal of Medicinal Food · doi:10.1177/1096620x261481601
Bifidobacterium adolescentis attenuates brown adipose tissue whitening and improves metabolic markers in high-fat diet-induced obese rats
Mehboodi, M., Khodayar, A., Namavar, N., atigh, T. Z. G., Zeynali, T., Mardi, F. H., Alnaqeeb, A., Bagheri, Z., Alinejad, M., Fard, M. H., et al. (2026) · DARU Journal of Pharmaceutical Sciences · doi:10.1007/s40199-026-00642-w
Unravelling Probiotic-Associated Traits and Protective Efficacy of Limosilactobacillus fermentum Strains Against Colitis
Das, M., Biswas, P., Ghosh, R., Nandi, A., Biswas, R., Kar, T. K., Chattopadhyay, S., & Dam, S. (2026) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-026-11211-7
LC2767 Alleviates Cholestatic Liver Injury and Fibrosis in Bile Duct‐Ligated Mice
Lee, D.-Y., Jang, H., Shin, J., Shin, Y., Kim, S. H., Han, S.-W., & Kim, D. (2026) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.70803
Self-citation

Simultaneous Amelioratation of Colitis and Liver Injury in Mice by Bifidobacterium longum LC67 and Lactobacillus plantarum LC27
Jang, S., Jeong, J.-J., Kim, J.-K., Han, M. J., & Kim, D. (2018) · Scientific Reports · doi:10.1038/s41598-018-25775-0 · Cited by 85 · see citing works
Self-citation
Bifidobacterium adolescentis IM38 ameliorates high-fat diet–induced colitis in mice by inhibiting NF-κB activation and lipopolysaccharide production by gut microbiota
Lim, S.-M., & Kim, D. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.04.003 · Cited by 98 · see citing works
Self-citation
Effects of a probiotic intervention on Escherichia coli and high-fat diet-induced intestinal microbiota imbalance
Sun, Q., Zhang, S., Liu, X., Huo, Y., Su, B., & Li, X. (2019) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-019-10304-4 · Cited by 32 · see citing works
Lactiplantibacillus plantarum dfa1 Outperforms Enterococcus faecium dfa1 on Anti-Obesity in High Fat-Induced Obesity Mice Possibly through the Differences in Gut Dysbiosis Attenuation, despite the Similar Anti-Inflammatory Properties
Ondee, T., Pongpirul, K., Janchot, K., Kanacharoen, S., Lertmongkolaksorn, T., Wongsaroj, L., Somboonna, N., Ngamwongsatit, N., & Leelahavanichkul, A. (2021) · Nutrients · doi:10.3390/nu14010080 · Cited by 36 · see citing works
Probiotics ameliorate chronic low-grade inflammation and fat accumulation with gut microbiota composition change in diet-induced obese mice models
Joung, H., Chu, J., Kim, B.-K., Choi, I.-S., Kim, W., & Park, T. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-020-11060-6 · Cited by 41 · see citing works

Authors: In Kim, H., Kim, J.-K., Kim, J.-Y., Jang, S.-E., Han, M. J., & Kim, D.-H.
Affiliations: Kyung Hee University (KR)
Eulji University (KR)
Corresponding author: Han, Myung Joo
Kim, Dong-Hyun
ORCID: Kim, Jeon-Kyung
Kim, Jae-Young
Jang, Se-Eun
Han, Myung Joo
Kim, Dong-Hyun
Venue: Nutrition Research
Publisher: Elsevier BV
Published: 2019-07
Volume: 67
Pages: 78-89
ISSN: 0271-5317 (ISSN-L)
DOI: 10.1016/j.nutres.2019.03.008
OpenAlex: W2923125589
Cited by: 82
References: 39
Citations by year: 2026: 12 · 2025: 11 · 2024: 12 · 2023: 11 · 2022: 13 · 2021: 8 · 2020: 13 · 2019: 2
FWCI: 6.95
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Nutrition Research (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Keywords: Lactobacillus plantarum, Bifidobacterium longum, probiotics, high-fat diet, colitis, endotoxemia, hepatic steatosis, obesity, NF-κB, AMPK, gut microbiota, lipopolysaccharide, intestinal barrier, claudin-1, occludin, Firmicutes, Proteobacteria, Caco-2 cells
MeSH terms: Gastrointestinal Microbiome, Bifidobacterium longum, Animals, Colitis, Colon, Disease Models, Animal, Fatty Liver, Male, Mice, Inbred C57BL, Obesity, Endotoxemia, Probiotics, Lactobacillus plantarum, Lactiplantibacillus plantarum, Mice, Diet, High-Fat

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 simultaneously alleviate high-fat diet-induced colitis, endotoxemia, liver steatosis, and obesity in mice

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks