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Dose-Response Analysis Using R
Open accessAbstract
Dose-response analysis can be carried out using multi-purpose commercial statistical software, but except for a few special cases the analysis easily becomes cumbersome as relevant, non-standard output requires manual programming. The extension package drc for the statistical environment R provides a flexible and versatile infrastructure for dose-response analyses in general. The present version of the package, reflecting extensions and modifications over the last decade, provides a user-friendly interface to specify the model assumptions about the dose-response relationship and comes with a number of extractors for summarizing fitted models and carrying out inference on derived parameters. The aim of the present paper is to provide an overview of state-of-the-art dose-response analysis, both in terms of general concepts that have evolved and matured over the years and by means of concrete examples.
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Metadata
- Authors
- Ritz, C., Baty, F., Streibig, J. C., & Gerhard, D.
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2015-12-30
- Volume
- 10
- Issue
- 12
- Pages
- e0146021
- ISSN
- 1932-6203 (ISSN-L)
- OpenAlex
- W2212640525
- Cited by
- 3,658
- References
- 3
- FWCI
- 96.03
- Type
- journal article
- Language
- en
- Open access
- gold
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