Effect of MBSR, DBT and CBT on the hypertension patients with depression/anxiety: Protocol of a systematic review and Bayesian network meta-analysis
Open accessAbstract
INTRODUCTION: Hypertension, one of the most common chronic diseases worldwide, usually requires lifetime managing blood pressure (BP) with medications. Due to quite large number of hypertension patients co-exist with depression and/or anxiety, and non-cooperated with medical instruction, consequently management of BP is impaired with serious complications, resulting in compromised quality of life. Consequently quality of life of such patients is impaired with serious complications. Therefore, management of depression and/or anxiety is equally important as the treatment of hypertension. Depression and/or anxiety are independent risk factors of hypertension, which is supported by the finding that there is close correlation between hypertension are depression/or anxiety. Psychotherapy (non-drug treatment) maybe useful for hypertensive patients with depression and/or anxiety to improve their negative emotions. We aim to quantify the effective of psychological therapies in the management of hypertension patients with depression or anxiety, by comparing and ranking a network meta-analysis (NMA). MATERIALS AND METHODS: Literature search for randomized controlled trials (RCTs) will be performed in five electronic databases from inception to December 2021, including PubMed, the Cochrane library, Embase, Web of Science, and China Biology Medicine disc (CBM). The search terms mainly include "hypertension", "mindfulness-based stress reduction" (MBSR), "cognitive behavioral therapy" (CBT) and "dialectical behavior therapy" (DBT). Cochrane Collaboration quality assessment tool will be used for the risk of bias assessment. A Bayesian network meta-analysis will be performed, using WinBUGS 1.4.3, and Stata 14 will be applied to draw the network diagram, while RevMan 5.3.5 will be used to produce funnel plot for assessing the risk of publication bias. Recommended rating, development and grade methodology will also be utilized to assess the quality of evidence. RESULTS: Effect of MBSR, CBT and DBT will be evaluated by traditional meta-analysis directly and Bayesian network meta-analysis indirectly. Our study will provide the evidence on the efficacy and safety of psychological treatments in the hypertension patients with anxiety. There is no research ethical requirement because this is a systematic review of published literature. The results of this study will be published in a peer-reviewed journal. TRIAL REGISTRATION: Prospero registration number: CRD42021248566.
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Our results contrast with those of previous studies examining mindfulness-based cognitive therapy.
“Our results contrast with those of previous studies examining mindfulness-based cognitive therapy (Zhang et al., 2023).”
From Analysis of the Efficacy of Mindfulness Meditation in a Mutual Aid Group for Bipolar Disorder (2024) · cites this paper as Zhang et al., 2023
The Methods/Design inclusion criteria (section 2.2; page unavailable) specify MBSR, CBT, and DBT—not mindfulness-based cognitive therapy—as the interventions to be examined. The Abstract’s Results section (page unavailable) says their effects *will be evaluated*: this is a protocol, not a study reporting results with which the citing authors could contrast their own. (LLM, conf=0.88)
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- Authors
- Zhang, Y., Zhang, H., Zhang, Y., Yang, Z., Wang, L., Pan, W., Dai, R., Ju, Q., Ren, D., Bao, S., & Fan, J.
- Affiliations
- Gansu University of Traditional Chinese Medicine (CN)
- Sichuan University (CN)
- Corresponding author
- Ren, Dong
- Bao, Shisan
- Fan, Jingchun
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2023-02-21
- Volume
- 18
- Issue
- 2
- Pages
- e0281469
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC9943006
- OpenAlex
- W4321440673
- Cited by
- 4
- References
- 26
- Citations by year
- 2025: 2 · 2024: 2
- FWCI
- 0.20
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- the 2020 Science and Technology Project of Chengguan District, Lanzhou (2020-2-11-16)
- the Talent Introduction Program of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine (2016YJRC-01)
- the University Innovation Capacity Improvement Project in Gansu Province (2020B-153)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- hypertension, depression, anxiety, mindfulness-based stress reduction, dialectical behavior therapy, cognitive behavioral therapy, psychotherapy, psychological intervention, blood pressure control, quality of life
- MeSH terms
- Network Meta-Analysis as Topic, Network Meta-Analysis, Systematic Reviews as Topic, Anxiety, Depression, Humans, Hypertension, Psychotherapy, Meta-Analysis as Topic, Cognitive Behavioral Therapy
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