Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Mortazavi, A., Williams, B. A., McCue, K., Schaeffer, L., & Wold, B. (2008) · Nature Methods · doi:10.1038/nmeth.1226 · Cited by 13,696 · see citing works

Exponentially Modified Protein Abundance Index (emPAI) for Estimation of Absolute Protein Amount in Proteomics by the Number of Sequenced Peptides per Protein

Ishihama, Y., Oda, Y., Tabata, T., Sato, T., Nagasu, T., Rappsilber, J., & Mann, M. (2005) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m500061-mcp200 · Cited by 2,055 · see citing works

Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity

Hewitson, J. P., Grainger, J. R., & Maizels, R. M. (2009) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2009.04.008 · Cited by 729 · see citing works

Suppression of allergic airway inflammation by helminth-induced regulatory T cells

Wilson, M. S., Taylor, M. D., Balic, A., Finney, C. A. M., Lamb, J. R., & Maizels, R. M. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20042572 · Cited by 611 · see citing works

Helminth Infections and Host Immune Regulation

McSorley, H. J., & Maizels, R. M. (2012) · Clinical Microbiology Reviews · doi:10.1128/cmr.05040-11 · Cited by 548 · see citing works

The CAP Superfamily: Cysteine-Rich Secretory Proteins, Antigen 5, and Pathogenesis-Related 1 Proteins—Roles in Reproduction, Cancer, and Immune Defense

Gibbs, G. M., Roelants, K., & O’Bryan, M. K. (2008) · Endocrine Reviews · doi:10.1210/er.2008-0032 · Cited by 497 · see citing works

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

Grainger, J. R., Smith, K. A., Hewitson, J. P., McSorley, H. J., Harcus, Y., Filbey, K. J., Finney, C. A. M., Greenwood, E. J. D., Knox, D. P., Wilson, M. S., et al. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20101074 · Cited by 469 · see citing works

Structural Biology of Shared Cytokine Receptors

Wang, X., Lupardus, P. J., LaPorte, S. L., & García, K. C. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.24.021605.090616 · Cited by 407 · see citing works

Inhibition of the Complement Cascade by the Major Secretory Protein of Vaccinia Virus

Kotwal, G. J., Isaacs, S. N., McKenzie, R., Frank, M. M., & Moss, B. (1990) · Science · doi:10.1126/science.2237434 · Cited by 320 · see citing works

Structure-function relationships of the complement components

Reid, K. B. M., & Day, A. J. (1989) · Immunology Today · doi:10.1016/0167-5699(89)90317-4 · Cited by 306 · see citing works

Heligmosomoides polygyrus inhibits established colitis in IL‐10‐deficient mice

Elliott, D. E., Setiawan, T., Metwali, A., Blum, A. M., Urban, J. F., & Weinstock, J. V. (2004) · European Journal of Immunology · doi:10.1002/eji.200324833 · Cited by 280 · see citing works

A hookworm glycoprotein that inhibits neutrophil function is a ligand of the integrin CD11b/CD18

Moyle, M., Foster, D. L., McGrath, D. E., Brown, S. M., Laroche, Y., De Meutter, J., Stanssens, P., Bogowitz, C. A., Fried, V. A., & Ely, J. A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36982-x · Cited by 253 · see citing works

The secretome of the filarial parasite, Brugia malayi: Proteomic profile of adult excretory–secretory products

Hewitson, J. P., Harcus, Y. M., Curwen, R. S., Dowle, A., Atmadja, A. K., Ashton, P. D., Wilson, A., & Maizels, R. M. (2008) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2008.02.007 · Cited by 242 · see citing works

An Enteric Helminth Infection Protects Against an Allergic Response to Dietary Antigen

Bashir, M. E. H., Andersen, P. S., Fuss, I. J., Shi, H. N., & Nagler‐Anderson, C. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.6.3284 · Cited by 234 · see citing works

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

Reynolds, L. A., Filbey, K. J., & Maizels, R. M. (2012) · Seminars in Immunopathology · doi:10.1007/s00281-012-0347-3 · Cited by 233 · see citing works

Comprehensive Analysis of the Secreted Proteins of the Parasite Haemonchus contortus Reveals Extensive Sequence Variation and Differential Immune Recognition

Yatsuda, A. P., Krijgsveld, J., Cornelissen, A. W. C. A., Heck, A. J. R., & de Vries, E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212453200 · Cited by 217 · see citing works

Expansion and activation of CD4+CD25+ regulatory T cells in Heligmosomoides polygyrus infection

Finney, C. A. M., Taylor, M. D., Wilson, M. S., & Maizels, R. M. (2007) · European Journal of Immunology · doi:10.1002/eji.200636751 · Cited by 216 · see citing works

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

Chi, V., Pennington, M. W., Norton, R. S., Tarcha, E. J., Londono, L. M., Sims-Fahey, B., Upadhyay, S. K., Lakey, J. R. T., Iadonato, S. P., Wulff, H., et al. (2011) · Toxicon · doi:10.1016/j.toxicon.2011.07.016 · Cited by 212 · see citing works

Brugia malayi Excreted/Secreted Proteins at the Host/Parasite Interface: Stage- and Gender-Specific Proteomic Profiling

Bennuru, S., Semnani, R. T., Meng, Z., Ribeiro, J. M. C., Veenstra, T. D., & Nutman, T. B. (2009) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0000410 · Cited by 198 · see citing works

Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone

Tudor, J. E., Pallaghy, P. K., Pennington, M. W., & Norton, R. S. (1996) · Nature Structural & Molecular Biology · doi:10.1038/nsb0496-317 · Cited by 191 · see citing works

Proteomics Analysis of the Excretory/Secretory Component of the Blood-feeding Stage of the Hookworm, Ancylostoma caninum

Mulvenna, J. P., Hamilton, B. R., Nagaraj, S. H., Smyth, D. J., Loukas, A. C., & Gorman, J. J. (2008) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m800206-mcp200 · Cited by 182 · see citing works

Helminth‐induced CD19+CD23hi B cells modulate experimental allergic and autoimmune inflammation

Wilson, M. S., Taylor, M. D., O’Gorman, M. T., Balic, A., Barr, T. A., Filbey, K. J., Anderton, S. M., & Maizels, R. M. (2010) · European Journal of Immunology · doi:10.1002/eji.200939721 · Cited by 180 · see citing works

Vaccines to combat the neglected tropical diseases

Bethony, J. M., Cole, R. N., Guo, X., Kamhawi, S., Lightowlers, M. W., Loukas, A. C., Petri, W. A., Reed, S. G., Valenzuela, J. G., & Hotez, P. J. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00976.x · Cited by 172 · see citing works

Polyclonal and Specific Antibodies Mediate Protective Immunity against Enteric Helminth Infection

McCoy, K. D., Stoel, M., Stettler, R., Merky, P., Fink, K., Senn, B. M., Schaer, C., Massacand, J. C., Odermatt, B., Oettgen, H. C., et al. (2008) · Cell Host & Microbe · doi:10.1016/j.chom.2008.08.014 · Cited by 165 · see citing works

Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of Venom Allergen-Like (VAL) proteins

Hewitson, J. P., Harcus, Y. M., Murray, J., van Agtmaal, M., Filbey, K. J., Grainger, J. R., Bridgett, S., Blaxter, M., Ashton, P. D., Ashford, D. A., et al. (2011) · Journal of Proteomics · doi:10.1016/j.jprot.2011.06.002 · Cited by 160 · see citing works

A portrait of the “SCP/TAPS” proteins of eukaryotes — Developing a framework for fundamental research and biotechnological outcomes

Cantacessi, C., Campbell, B. E., Visser, A., Geldhof, P., Nolan, M. J., Nisbet, A. J., Matthews, J. B., Loukas, A. C., Hofmann, A., Otranto, D., et al. (2009) · Biotechnology Advances · doi:10.1016/j.biotechadv.2009.02.005 · Cited by 156 · see citing works

Serine proteinase inhibitors from nematodes and the arms race between host and pathogen

Zang, X., & Maizels, R. M. (2001) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01761-8 · Cited by 147 · see citing works

Immune modulation and modulators in Heligmosomoides polygyrus infection

Maizels, R. M., Hewitson, J. P., Murray, J., Harcus, Y. M., Dayer, B., Filbey, K. J., Grainger, J. R., McSorley, H. J., Reynolds, L. A., & Smith, K. A. (2011) · Experimental Parasitology · doi:10.1016/j.exppara.2011.08.011 · Cited by 141 · see citing works

Heligmosomoides polygyrus: A model for chronic gastrointestinal helminthiasis

Monroy, F., & Enriquez, F. J. (1992) · Parasitology Today · doi:10.1016/0169-4758(92)90084-f · Cited by 134 · see citing works

Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier

Hasnain, S. Z., McGuckin, M. A., Grencis, R. K., & Thornton, D. J. (2012) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0001856 · Cited by 121 · see citing works

Heligmosomoides polygyrusPromotes Regulatory T-Cell Cytokine Production in the Murine Normal Distal Intestine

Setiawan, T., Metwali, A., Blum, A. M., Ince, M. N., Urban, J. F., Elliott, D. E., & Weinstock, J. V. (2007) · Infection and Immunity · doi:10.1128/iai.00358-07 · Cited by 116 · see citing works

Highly sensitive and specific bioassay for measuring bioactive TGF-β

Tesseur, I. C., Zou, K., Berber, E., Zhang, H., & Wyss‐Coray, T. (2006) · BMC Cell Biology · doi:10.1186/1471-2121-7-15 · Cited by 115 · see citing works

Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode Infection

Rausch, S., Huehn, J., Kirchhoff, D., Rzepecka, J., Schnoeller, C., Pillai, S., Loddenkemper, C., Scheffold, A., Hamann, A., Lucius, R., et al. (2008) · Infection and Immunity · doi:10.1128/iai.01233-07 · Cited by 113 · see citing works

Ancylostoma caninum MTP-1, an Astacin-Like Metalloprotease Secreted by Infective Hookworm Larvae, Is Involved in Tissue Migration

Williamson, A., Lustigman, S., Oksov, Y., Deumic, V., Plieskatt, J. L., Méndez, S., Zhan, B., Bottazzi, M. E., Hotez, P. J., & Loukas, A. C. (2006) · Infection and Immunity · doi:10.1128/iai.74.2.961-967.2006 · Cited by 107 · see citing works

A Research Agenda for Helminth Diseases of Humans: Towards Control and Elimination

Boatin, B. A., Basáñez, M.-G., Prichard, R. K., Awadzi, K., Barakat, R. M. R., García, H. H., Gazzinelli, A., Grant, W. N., McCarthy, J. S., N'Goran, E. K., et al. (2012) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0001547 · Cited by 105 · see citing works

A Family of Secreted Mucins from the Parasitic Nematode Toxocara canis Bears Diverse Mucin Domains but Shares Similar Flanking Six-cysteine Repeat Motifs

Loukas, A. C., Hintz, M., Linder, D., Mullin, N. P., Parkinson, J., Tetteh, K. K. A., & Maizels, R. M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m005632200 · Cited by 99 · see citing works

An Abundant, trans-spliced mRNA from Toxocara canis Infective Larvae Encodes a 26-kDa Protein with Homology to Phosphatidylethanolamine-binding Proteins

Gems, D., Ferguson, C. J., Robertson, B. D., Nieves, R., Page, A. P., Blaxter, M., & Maizels, R. M. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.31.18517 · Cited by 98 · see citing works

Genetic control of immunity to Nematospiroides dubius: a 9‐day anthelmintic abbreviated immunizing regime which separates weak and strong responder strains of mice

Behnke, J. M., & ROBINSON, M. (1985) · Parasite Immunology · doi:10.1111/j.1365-3024.1985.tb00073.x · Cited by 98 · see citing works

Proteomic Analysis of Excretory-Secretory Products of Heligmosomoides polygyrus Assessed with Next-Generation Sequencing Transcriptomic Information

Moreno, Y., Gros, P.-P., Tam, M., Segura, M., Valanparambil, R. M., Geary, T. G., & Stevenson, M. M. (2011) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0001370 · Cited by 97 · see citing works

Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia

Bennuru, S., Meng, Z., Ribeiro, J. M. C., Semnani, R. T., Ghedin, E., Chan, K. C., Lucas, D. A., Veenstra, T. D., & Nutman, T. B. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1011481108 · Cited by 95 · see citing works

A Broad Spectrum Kunitz Type Serine Protease Inhibitor Secreted by the Hookworm Ancylostoma ceylanicum

Milstone, A. M., Harrison, L. M., Bungiro, R. D., Kuzmič, P., & Cappello, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002715200 · Cited by 90 · see citing works

Pharmaceutical treatments of gastrointestinal nematode infections of sheep—Future of anthelmintic drugs

Sargison, N. D. (2012) · Veterinary Parasitology · doi:10.1016/j.vetpar.2012.03.035 · Cited by 84 · see citing works

Chronic Helminth Infection Promotes Immune Regulation In Vivo through Dominance of CD11cloCD103− Dendritic Cells

Smith, K. A., Hochweller, K., Hämmerling, G. J., Boon, L., MacDonald, A. S., & Maizels, R. M. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1003636 · Cited by 83 · see citing works

Heligmosomoides polygyrus bakeri Induces Tolerogenic Dendritic Cells that Block Colitis and Prevent Antigen-Specific Gut T Cell Responses

Blum, A. M., Hang, L., Setiawan, T., Urban, J. P., Stoyanoff, K. M., Leung, J., & Weinstock, J. V. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1102892 · Cited by 80 · see citing works

Vaccination against helminth parasites ‐ the ultimate challenge for vaccinologists?

Maizels, R. M., Holland, M. J., Falcone, F. H., Zang, X., & Yazdanbakhsh, M. (1999) · Immunological Reviews · doi:10.1111/j.1600-065x.1999.tb01345.x · Cited by 78 · see citing works

Ancylostoma caninum: Metalloprotease Release Coincides with Activation of Infective Larvae in Vitro

Hawdon, J. M., Jones, B. F., Perregaux, M., & Hotez, P. J. (1995) · Experimental Parasitology · doi:10.1006/expr.1995.1025 · Cited by 77 · see citing works

Calreticulin from the intestinal nematode Heligmosomoides polygyrus is a Th2-skewing protein and interacts with murine scavenger receptor-A

Rzepecka, J., Rausch, S., Klotz, C., Schnoeller, C., Kornprobst, T., Hagen, J., Ignatius, R., Lucius, R., & Hartmann, S. (2008) · Molecular Immunology · doi:10.1016/j.molimm.2008.10.032 · Cited by 72 · see citing works

Proteomic analysis of excretory/secretory products released by Teladorsagia circumcincta larvae early post‐infection

Smith, S. K., Nisbet, A. J., MEIKLE, L. I., Inglis, N. F., Sales, J., Beynon, R. J., & Matthews, J. B. (2008) · Parasite Immunology · doi:10.1111/j.1365-3024.2008.01067.x · Cited by 72 · see citing works

The Life Cycle of Nematospiroides dubius, Baylis, 1926 (Nematoda: Heligmosomidae)

Bryant, V. (1973) · Journal of Helminthology · doi:10.1017/s0022149x00026535 · Cited by 72 · see citing works

Biochemical study andin vitroinsect immune suppression by a trypsin-like secreted protease from the nematodeSteinernema carpocapsae

Balasubramanian, N., Toubarro, D., & Simões, N. (2009) · Parasite Immunology · doi:10.1111/j.1365-3024.2009.01172.x · Cited by 71 · see citing works

Massively Parallel Sequencing and Analysis of the Necator americanus Transcriptome

Cantacessi, C., Mitreva, M., Jex, A. R., Young, N. D., Campbell, B. E., Hall, R. S., Doyle, M., Ralph, S. A., Rabelo, É. M. L., Ranganathan, S., et al. (2010) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0000684 · Cited by 69 · see citing works

A putative serine protease among the excretory–secretory glycoproteins of L1 Trichinella spiralis

Romarı́s, F., North, S. J., Gagliardo, L. F., Butcher, B. A., Ghosh, K., Beiting, D. P., Panico, M., Arasu, P., Dell, A., Morris, H. R., et al. (2002) · Molecular and Biochemical Parasitology · doi:10.1016/s0166-6851(02)00094-4 · Cited by 69 · see citing works

Heligmosomoides bakeri: a model for exploring the biology and genetics of resistance to chronic gastrointestinal nematode infections

Behnke, J. M., Menge, D. M., & Noyes, H. A. (2009) · Parasitology · doi:10.1017/s0031182009006003 · Cited by 67 · see citing works

daf-7-related TGF-β homologues from Trichostrongyloid nematodes show contrasting life-cycle expression patterns

McSorley, H. J., Grainger, J. R., Harcus, Y. M., Murray, J., Nisbet, A. J., Knox, D. P., & Maizels, R. M. (2009) · Parasitology · doi:10.1017/s0031182009990321 · Cited by 61 · see citing works

Heligmosomoides polygyrus Elicits a Dominant Nonprotective Antibody Response Directed against Restricted Glycan and Peptide Epitopes

Hewitson, J. P., Filbey, K. J., Grainger, J. R., Dowle, A., Pearson, M. S., Murray, J., Harcus, Y. M., & Maizels, R. M. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1004140 · Cited by 55 · see citing works

An immunogenic cathepsin F secreted by the parasitic stages of Teladorsagia circumcincta

Redmond, D. L., Smith, S. K., HALLIDAY, A. M., Smith, W. D., Jackson, F., Knox, D. P., & Matthews, J. B. (2005) · International Journal for Parasitology · doi:10.1016/j.ijpara.2005.10.011 · Cited by 54 · see citing works

Platyhelminth Venom Allergen-Like (VAL) proteins: revealing structural diversity, class-specific features and biological associations across the phylum

Chalmers, I. W., & Hoffmann, K. F. (2012) · Parasitology · doi:10.1017/s0031182012000704 · Cited by 47 · see citing works

Vaccinomics for the Major Blood Feeding Helminths of Humans

Loukas, A. C., Gaze, S. T., Mulvenna, J. P., Gasser, R. B., Brindley, P. J., Doolan, D. L., Bethony, J. M., Jones, M. K., Gobert, G. N., Driguez, P., et al. (2011) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2010.0150 · Cited by 44 · see citing works

Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi

Li, B.-W., Wang, Z., Rush, A. C., Mitreva, M., & Weil, G. J. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-184 · Cited by 42 · see citing works

Allergen‐specific immunosuppression by mucosal treatment with recombinant Ves v 5, a major allergen of Vespula vulgaris venom, in a murine model of wasp venom allergy

Winkler, B., Bolwig, C., Seppälä, U., Spangfort, M. D., Ebner, C., & Wiedermann, U. (2003) · Immunology · doi:10.1046/j.1365-2567.2003.01751.x · Cited by 42 · see citing works

Hookworm SCP/TAPS protein structure—A key to understanding host–parasite interactions and developing new interventions

Osman, A., Wang, C. K. L., Winter, A., Loukas, A. C., Tribolet, L., Gasser, R. B., & Hofmann, A. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.11.002 · Cited by 34 · see citing works

The phenotype and function of naturally existing regulatory dendritic cells in nematode-infected mice

Li, Z., Liu, G., Chen, Y., Liu, Y., Liu, B., & Su, Z. (2011) · International Journal for Parasitology · doi:10.1016/j.ijpara.2011.06.008 · Cited by 32 · see citing works

Teladorsagia circumcincta: Activation-associated secreted proteins in excretory/secretory products of fourth stage larvae are targets of early IgA responses in infected sheep

Nisbet, A. J., Smith, S. K., Armstrong, S. D., MEIKLE, L. I., WILDBLOOD, L. A., Beynon, R. J., & Matthews, J. B. (2010) · Experimental Parasitology · doi:10.1016/j.exppara.2010.02.014 · Cited by 29 · see citing works

Chitinase is stored and secreted from the inner body of microfilariae and has a role in exsheathment in the parasitic nematode Brugia malayi

Wu, Y., Preston, G., & Bianco, A. E. (2008) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2008.06.007 · Cited by 28 · see citing works

An AC-5 cathepsin B-like protease purified fromHaemonchus contortusexcretory secretory products shows protective antigen potential for lambs

de Vries, E., Bakker, N., Krijgsveld, J., Knox, D. P., Heck, A. J. R., & Yatsuda, A. P. (2009) · Veterinary Research · doi:10.1051/vetres/2009025 · Cited by 26 · see citing works

Stimulation of immunity to Nematospiroides dubius in mice using larvae attenuated by cobalt 60 irradiation

Hagan, P., Behnke, J. M., & PARISH, H. A. (1981) · Parasite Immunology · doi:10.1111/j.1365-3024.1981.tb00393.x · Cited by 26 · see citing works

Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum☆

Feng, J., Zhan, B., Liu, Y., Liu, S., Williamson, A., Goud, G. N., Loukas, A. C., & Hotez, P. J. (2007) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2007.01.001 · Cited by 22 · see citing works

Non-specific immunodepression by larval and adult Nematospiroides dubius

Ali, N. M. H., & Behnke, J. M. (1984) · Parasitology · doi:10.1017/s0031182000054421 · Cited by 21 · see citing works

Multiplex proteomics analysis of gender-associated proteins in Brugia malayi

Jiang, D., Malone, J. P., Townsend, R., Weil, G. J., & Li, B. (2012) · International Journal for Parasitology · doi:10.1016/j.ijpara.2012.06.004 · Cited by 6 · see citing works

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

Buck, A. H., Coakley, G., Simbari, F., McSorley, H. J., Quintana, J. F., Le Bihan, T., Kumar, S., Abreu-Goodger, C., Lear, M., Harcus, Y., et al. (2014) · Nature Communications · doi:10.1038/ncomms6488 · Cited by 770 · see citing works

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

Maizels, R. M., Smits, H. H., & McSorley, H. J. (2018) · Immunity · doi:10.1016/j.immuni.2018.10.016 · Cited by 435 · see citing works

Extracellular vesicles in parasitic diseases

Marcilla, A., Jaular, L. M., Trelis, M., Menezes‐Neto, A., Osuna, A., Bernal, D., Fernández-Becerra, C., de Almeida, I. C., & Portillo, H. A. D. (2014) · Journal of Extracellular Vesicles · doi:10.3402/jev.v3.25040 · Cited by 224 · see citing works

HpARI protein secreted by a helminth parasite suppresses interleukin-33

Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., le Bihan, T., et al. (2017) · Immunity · doi:10.1016/j.immuni.2017.09.015 · Cited by 178 · see citing works

Vaccination against helminth parasite infections

Hewitson, J. P., & Maizels, R. M. (2014) · Expert Review of Vaccines · doi:10.1586/14760584.2014.893195 · Cited by 123 · see citing works

Secreted Proteomes of Different Developmental Stages of the Gastrointestinal Nematode Nippostrongylus brasiliensis

Sotillo, J., Sánchez‐Flores, A., Cantacessi, C., Harcus, Y. M., Pickering, D., Bouchery, T., Camberis, M., Tang, S., Giacomin, P., Mulvenna, J. P., et al. (2014) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m114.038950 · Cited by 103 · see citing works

Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection

Hewitson, J. P., Filbey, K. J., Bieren, J. E., Camberis, M., Schwartz, C., Murray, J., Reynolds, L. A., Blair, N. F., Robertson, E., Harcus, Y. M., et al. (2015) · PLoS Pathogens · doi:10.1371/journal.ppat.1004676 · Cited by 99 · see citing works

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products

Johnston, C. J. C., Robertson, E., Harcus, Y. M., Grainger, J. R., Coakley, G., Smyth, D. J., McSorley, H. J., & Maizels, R. M. (2015) · Journal of Visualized Experiments · doi:10.3791/52412 · Cited by 93 · see citing works

Shared weapons of blood- and plant-feeding insects: Surprising commonalities for manipulating hosts

Guiguet, A., Dubreuil, G., Harris, M. O., Appel, H. M., Schultz, J. C., Pereira, M. H., & Giron, D. (2015) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2015.12.006 · Cited by 68 · see citing works

A helminth-derived suppressor of ST2 blocks allergic responses

Vacca, F., Chauché, C., Jamwal, A., Hinchy, E. C., Heieis, G. A., Webster, H. C., Ogunkanbi, A., Sekne, Z., Gregory, W. F., Wear, M. A., et al. (2020) · eLife · doi:10.7554/elife.54017 · Cited by 68 · see citing works

Immune modulation by helminth parasites of ruminants: implications for vaccine development and host immune competence

McNeilly, T. N., & Nisbet, A. J. (2014) · Parasite · doi:10.1051/parasite/2014051 · Cited by 67 · see citing works

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

Smyth, D. J., Harcus, Y., White, M. P. J., Gregory, W. F., Nahler, J., Stephens, I., Toke-Bjolgerud, E., Hewitson, J. P., Ivens, A., McSorley, H. J., et al. (2018) · International Journal for Parasitology · doi:10.1016/j.ijpara.2017.12.004 · Cited by 66 · see citing works

Harnessing the Helminth Secretome for Therapeutic Immunomodulators

Ditgen, D., Anandarajah, E. M., Meissner, K. A., Brattig, N. W., Wrenger, C., & Liebau, E. (2014) · BioMed Research International · doi:10.1155/2014/964350 · Cited by 64 · see citing works

Identifying the immunomodulatory components of helminths

Shepherd, C., Navarro, S., Wangchuk, P., Wilson, D. T. R., Daly, N. L., & Loukas, A. C. (2015) · Parasite Immunology · doi:10.1111/pim.12192 · Cited by 63 · see citing works

Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection

Dubey, L. K., Lebon, L., Mosconi, I., Yang, C.-Y., Scandella, E., Ludewig, B., Luther, S. A., & Harris, N. L. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.04.023 · Cited by 55 · see citing works

Comprehensive analysis of the secreted proteome of adult Necator americanus hookworms

Logan, J., Pearson, M. S., Manda, S. S., Choi, Y.-J., Field, M. A., Eichenberger, R. M., Mulvenna, J. P., Nagaraj, S. H., Fujiwara, R. T., Gazzinelli-Guimarães, P. H., et al. (2020) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0008237 · Cited by 47 · see citing works

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fcγ Receptor I

Bieren, J. E., Volpe, B., Kulagin, M., Sutherland, D. B., Guiet, R., Seitz, A., Marsland, B. J., Verbeek, J. S., & Harris, N. L. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1401645 · Cited by 40 · see citing works

IL-33: A central cytokine in helminth infections

McSorley, H. J., & Smyth, D. J. (2021) · Seminars in Immunology · doi:10.1016/j.smim.2021.101532 · Cited by 42 · see citing works

Production and analysis of immunomodulatory excretory-secretory products from the mouse gastrointestinal nematode Heligmosomoides polygyrus bakeri

Valanparambil, R. M., Segura, M., Tam, M., Jardim, A., Geary, T. G., & Stevenson, M. M. (2014) · Nature Protocols · doi:10.1038/nprot.2014.184 · Cited by 36 · see citing works

MyD88 Signaling Inhibits Protective Immunity to the Gastrointestinal Helminth Parasite Heligmosomoides polygyrus

Reynolds, L. A., Harcus, Y. M., Smith, K. A., Webb, L. M., Hewitson, J. P., Ross, E. A., Brown, S. L., Uematsu, S., Akira, S., Gray, D., et al. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1401056 · Cited by 34 · see citing works

Exploiting Helminth–Host Interactomes through Big Data

Sotillo, J., Toledo, R., Mulvenna, J. P., & Loukas, A. C. (2017) · Trends in Parasitology · doi:10.1016/j.pt.2017.06.011 · Cited by 34 · see citing works

Functional Diversity of the Excretory/Secretory Proteins of Nematode Parasites

Joshi, P., & Mishra, P. K. K. (2022) · Acta Parasitologica · doi:10.1007/s11686-022-00523-7 · Cited by 32 · see citing works

The root-knot nematode effector Mi2G02 hijacks a host plant trihelix transcription factor to promote nematode parasitism

Zhao, J., Huang, K., Liu, R., Lai, Y., Abad, P., Favery, B., Jian, H., Ling, J., Li, Y., Yang, Y., et al. (2023) · Plant Communications · doi:10.1016/j.xplc.2023.100723 · Cited by 31 · see citing works

Proteomic Analysis of Excretory-Secretory Products of Mesocestoides corti Metacestodes Reveals Potential Suppressors of Dendritic Cell Functions

Vendelova, E., de Lima, J. C., Lorenzatto, K. R., Monteiro, K. M., Mueller, T. D., Veepaschit, J., Grimm, C., Brehm, K., Hrčková, G., Lutz, M. B., et al. (2016) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0005061 · Cited by 31 · see citing works

Mining nematode protein secretomes to explain lifestyle and host specificity

Tritten, L., Ballesteros, C., Beech, R. N., Geary, T. G., & Moreno, Y. (2021) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0009828 · Cited by 27 · see citing works

Stage-specific Proteomes from Onchocerca ochengi, Sister Species of the Human River Blindness Parasite, Uncover Adaptations to a Nodular Lifestyle

Armstrong, S. D., Xia, D., Bah, G. S., Krishna, R., Ngangyung, H. F., LaCourse, E. J., McSorley, H. J., Kengne-Ouafo, J. A., Ndongmo, P. W. C., Wanji, S., et al. (2016) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m115.055640 · Cited by 27 · see citing works

Heligmosomoides polygyrus Venom Allergen-like Protein-4 (HpVAL-4) is a sterol binding protein

Asojo, O. A., Darwiche, R., Gebremedhin, S., Smant, G., Lozano‐Torres, J. L., Drurey, C., Pollet, J. B. K., Maizels, R. M., Schneiter, R., & Wilbers, R. H. P. (2018) · International Journal for Parasitology · doi:10.1016/j.ijpara.2018.01.002 · Cited by 27 · see citing works

Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-β to its receptors, TβRI and TβRII

Mukundan, A., Byeon, C., Hinck, C. S., Cunningham, K. T., Campion, T., Smyth, D. J., Maizels, R. M., & Hinck, A. P. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.101994 · Cited by 21 · see citing works

Niche-specific gene expression in a parasitic nematode; increased expression of immunomodulators in Teladorsagia circumcincta larvae derived from host mucosa

McNeilly, T., Frew, D., Burgess, S., Wright, H. W., Bartley, D., Bartley, Y., & Nisbet, A. (2017) · Scientific Reports · doi:10.1038/s41598-017-07092-0 · Cited by 22 · see citing works

The production of excretory-secretory molecules from Heligmosomoides polygyrus bakeri fourth stage larvae varies between mixed and single sex cultures

Maruszewska‐Cheruiyot, M., Szewczak, L., Krawczak, K., Głaczyńska, M., & Donskow‐Łysoniewska, K. (2021) · Parasites & Vectors · doi:10.1186/s13071-021-04613-9 · Cited by 19 · see citing works

Zoonotic intestinal helminths interact with the canine immune system by modulating T cell responses and preventing dendritic cell maturation

Junginger, J., Raue, K., Wolf, K., Janecek, E., Stein, V. M., Tipold, A., Günzel‐Apel, A., Strübe, C., & Hewicker‐Trautwein, M. (2017) · Scientific Reports · doi:10.1038/s41598-017-10677-4 · Cited by 19 · see citing works

Novel O -linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus

Hewitson, J. P., Nguyen, D. L., van Diepen, A., Smit, C. H., Koeleman, C. A. M., McSorley, H. J., Murray, J., Maizels, R. M., & Hokke, C. H. (2015) · International Journal for Parasitology · doi:10.1016/j.ijpara.2015.10.004 · Cited by 19 · see citing works

The helminth parasite proteome at the host-parasite interface - Informing diagnosis and control.

van der Ree, A. M., & Mutapi, F. (2015) · Experimental parasitology · doi:10.1016/j.exppara.2015.06.007 · Cited by 20 · see citing works

Enteric nematodes and the path to up-regulation of type 2 cytokines IL-4 and IL-13

Shea‐Donohue, T., Sun, R., Bohl, J. A., McLean, L. P., & Zhao, A. (2015) · Cytokine · doi:10.1016/j.cyto.2015.06.007 · Cited by 18 · see citing works

Cytokines from parasites: manipulating host responses by molecular mimicry

Maizels, R. M., McSorley, H. J., Smits, H. H., ten Dijke, P., & Hinck, A. P. (2025) · Biochemical Journal · doi:10.1042/bcj20253061 · Cited by 17 · see citing works

Trichuris trichiura egg extract proteome reveals potential diagnostic targets and immunomodulators

Cruz, K., Marcilla, A., Kelly, P. J., Vandenplas, M. L., Osuna, A., & Trelis, M. (2021) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0009221 · Cited by 16 · see citing works

Transgenic expression of a T cell epitope in Strongyloides ratti reveals that helminth-specific CD4+ T cells constitute both Th2 and Treg populations

Douglas, B. B., Wei, Y. Q., Li, X., Ferguson, A. A., Hung, L., Pastore, C., Kurtz, J. R., McLachlan, J. B., Nolan, T. J., Lok, J. B., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009709 · Cited by 14 · see citing works

Excretory/secretory proteins of adult Toxocara canis induce changes in the expression of proteins involved in the NOD1-RIP2-NF-κB pathway and modulate cytokine production in mouse macrophages

Li, F., Li, X. L., Chen, S., Tan, C., Mei, S. P., Jia, H., Song, Z., & Zhou, R. Q. (2021) · Experimental Parasitology · doi:10.1016/j.exppara.2021.108152 · Cited by 14 · see citing works

Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire

Brown, I. K., Dyjack, N. T., Miller, M. M., Krovi, S. H., Rios, C. L., Woolaver, R. A., Harmacek, L. D., Tu, T.-H. C., O’Connor, B. P., Danhorn, T., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009602 · Cited by 13 · see citing works

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products

Johnston, C. J. C., Robertson, E., Harcus, Y. M., Grainger, J. R., Coakley, G., Smyth, D. J., McSorley, H. J., & Maizels, R. M. (2015) · Journal of Visualized Experiments · doi:10.3791/52412-v · Cited by 13 · see citing works

Characterisation of the secreted apyrase family of Heligmosomoides polygyrus

Berkachy, R., Smyth, D. J., Schnoeller, C., Harcus, Y. M., Maizels, R. M., Selkirk, M. E., & Gounaris, K. (2020) · International Journal for Parasitology · doi:10.1016/j.ijpara.2020.07.011 · Cited by 12 · see citing works

Targeted transcriptomics reveals signatures of large-scale independent origins and concerted regulation of effector genes in Radopholus similis

Vieira, P. C., Myers, R., Pellegrin, C., Wram, C. L., Hesse, C. N., Maier, T. R., Shao, J. Y., Koutsovoulos, G., Zasada, I. A., Matsumoto, T. K., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1010036 · Cited by 12 · see citing works

Protein families secreted by nematodes to modulate host immunity

Colomb, F., & McSorley, H. J. (2025) · Current Opinion in Microbiology · doi:10.1016/j.mib.2025.102582 · Cited by 10 · see citing works

L4 stage Heligmosomoides polygyrus prevents the maturation of dendritic JAWS II cells

Maruszewska‐Cheruiyot, M., Donskow‐Łysoniewska, K., Piechna, K., Krawczak, K., & Doligalska, M. (2018) · Experimental Parasitology · doi:10.1016/j.exppara.2018.10.010 · Cited by 11 · see citing works

Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection

Smyth, D. J., Hodge, S. H., Ong, N. W. P., Richards, J., Colomb, F., Carmine, S. D., Shek, V., Frangova, T. G., Poveda, M. C., Maizels, R. M., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115721 · Cited by 9 · see citing works

Convergent Evolution in a Murine Intestinal Parasite Rapidly Created the TGM Family of Molecular Mimics to Suppress the Host Immune Response

Maizels, R. M., & Newfeld, S. J. (2023) · Genome Biology and Evolution · doi:10.1093/gbe/evad158 · Cited by 9 · see citing works

TGM6 is a helminth secretory product that mimics TGF-β binding to TGFBR2 to antagonize signaling in fibroblasts

White, S. E., Schwartze, T. A., Mukundan, A., Schoenherr, C., Singh, S. P., van Dinther, M., Cunningham, K. T., White, M. P. J., Campion, T., Pritchard, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-56954-z · Cited by 9 · see citing works

HpBoRB, a helminth-derived CCP domain protein which binds RELMβ

Shek, V., Jamwal, A., Smyth, D. J., Frangova, T. G., Savage, A. R., Kelly, S., Wright, G. J., Toth, R. L., Schwarz, E. M., Maizels, R. M., et al. (2025) · International Journal for Parasitology · doi:10.1016/j.ijpara.2025.09.006 · Cited by 6 · see citing works

Calendula officinalis Triterpenoid Saponins Impact the Immune Recognition of Proteins in Parasitic Nematodes

Doligalska, M., Jóźwicka, K., Szewczak, L., Nowakowska, J., Brodaczewska, K. K., Goździk, K., Pączkowski, C., & Szakiel, A. (2021) · Pathogens · doi:10.3390/pathogens10030296 · Cited by 6 · see citing works

Unveiling Novel Insights in Helminth Proteomics: Advancements, Applications, and Implications for Parasitology and Beyond

Soleymani, N., Sadr, S., Santucciu, C., Dianaty, S., Lotfalizadeh, N., Hajjafari, A., Heshmati, F., & Borji, H. (2024) · Biologics · doi:10.3390/biologics4030020 · Cited by 5 · see citing works

Comprehensive analysis of human hookworm secreted proteins using a proteogenomic approachPreprint

Logan, J., Manda, S. S., Choi, Y., Field, M. A., Eichenberger, R. M., Mulvenna, J. P., Nagaraj, S. H., Fujiwara, R., Gazzinelli-Guimarães, P. H., Bueno, L. L., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/406843 · Cited by 4 · see citing works

TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblastsPreprint

White, S. E., Schwartze, T. A., Mukundan, A., Schoenherr, C., Singh, S. P., van Dinther, M., Cunningham, K. T., White, M. P. J., Campion, T., Pritchard, J., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.22.573140 · Cited by 4 · see citing works

Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host’s immune system

Schwarz, E. M., Noon, J., Chicca, J., Garceau, C., Li, H., Antoshechkin, I. A., Ilík, V., Pafčo, B., Weeks, A. M., Homan, E. J., et al. (2026) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0014106 · Cited by 3 · see citing works

Immunization with excretory‐secretory molecules of intestinal nematodes induces antigen‐specific protective memory Th2 cell responses

Yordanova, I. A., Elizalde‐Velázquez, L. E., & Hartmann, S. (2023) · European Journal of Immunology · doi:10.1002/eji.202250237 · Cited by 3 · see citing works

The intestinal milieu influences the immunoproteome of male and femaleHeligmosomoides polygyrus bakeriL4 stage

Maruszewska‐Cheruiyot, M., Donskow‐Łysoniewska, K., Krawczak, K., Szewczak, L., Joachimiak, E., & Doligalska, M. (2020) · Parasitology · doi:10.1017/s0031182020001201 · Cited by 3 · see citing works

Structure-based mapping of the TβRI and TβRII receptor binding sites of the parasitic TGF-β mimic, Hp-TGMPreprint

Mukundan, A., Byeon, C., Hinck, C. S., Smyth, D. J., Maizels, R. M., & Hinck, A. P. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.08.416701 · Cited by 3 · see citing works

Characterization and ligand binding properties of a fatty acid- and retinol- binding protein (Hp-FAR-2) from Heligmosomoides polygyrus

Azizpor, P., Montoya, J., Eyabi, F., Ramirez, J., Hill, T., Pena, R., Mishra, M., Boulanger, M. J., & Dillman, A. R. (2025) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0013198 · Cited by 2 · see citing works

Tonic for your GIN: gastrointestinal nematode immunomodulator vaccines

McSorley, H. J., Smyth, D. J., & Fisher, G. (2026) · Trends in Parasitology · doi:10.1016/j.pt.2026.01.012 · Cited by 2 · see citing works

Helminth therapy – local and systemic activity, on example of inflammatory bowel diseases and multiple sclerosis

Maruszewska‐Cheruiyot, M., Donskow‐Łysoniewska, K., & Doligalska, M. (2019) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.5604/01.3001.0013.6092 · Cited by 2 · see citing works

2-D organoids demonstrate specificity in the interactions of parasitic nematodes and their secreted products at the basal or apical intestinal epitheliumPreprint

White, R. F., Bermúdez‐Barrientos, J. R., Robertson, E., Correa, M. A. D., & Buck, A. H. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.16.628471 · Cited by 2 · see citing works

Exploring the repertoire of rhomboid proteases in Cryptosporidium parvum parasite: phylogenesis, structural motifs, and cellular localization in sporozoite cells

Vanni, I., Pizzi, E., Bertuccini, L., Ludovisi, A., & Tosini, F. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1733450 · Cited by 1 · see citing works

Adrenergic signaling during parasitic infections

Gardias, P., & Bąska, P. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1691005 · Cited by 1 · see citing works

Liver-draining portal lymph node responds to enteric nematode infection by generating highly parasite-specific follicular T helper and B cell responses

Adjah, J., Musimbi, Z. D., Mugo, R. M., Midha, A., Hartmann, S., & Rausch, S. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1483274 · Cited by 1 · see citing works

Proteomic Analysis Of Trichuris Trichiura Egg Extract Reveals Potential Immunomodulators And Diagnostic TargetsPreprint

Cruz, K., Marcilla, A., Kelly, P., Vandenplas, M. L., Osuna, A., & Trelis, M. (2020) · doi:10.21203/rs.3.rs-44877/v1 · Cited by 1 · see citing works

Heligmosomoides polygyrus Parasite to the Gastrointestinal Helminth MyD88 Signaling Inhibits Protective

Maizels, R. M., MacDonald, A. S., Cunningham, A. F., Uematsu, S., Akira, S., Gray, D., Webb, M., Hewitson, J. P., Ross, E. A., Reynolds, A. B., et al. (2014)

Faculty Opinions recommendation of HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.

Nutman, T. B. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.732005506.793551828

A secreted fatty acid- and retinol- binding protein from Heligmosomoides polygyrus suppresses host macrophage polarizationPreprint

Azizpor, P., Montoya, J., Eyabi, F., Ramirez, J., Hill, T., Pena, R., Mishra, M., Boulanger, M. J., & Dillman, A. R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.05.657999

Epithelial cytokines in soil-transmitted helminth infections

McSorley, H. J., & Hodge, S. H. (2025) · Advances in Parasitology/Advances in parasitology · doi:10.1016/bs.apar.2025.07.005 · Cited by 1 · see citing works

Additional file 1 of The production of excretory-secretory molecules from Heligmosomoides polygyrus bakeri fourth stage larvae varies between mixed and single sex cultures

Maruszewska‐Cheruiyot, M., Szewczak, L., Krawczak, K., Głaczyńska, M., & Donskow‐Łysoniewska, K. (2021) · Figshare · doi:10.6084/m9.figshare.13788228

Differential generation of parasite-specific Th2 and T follicular helper cells distinguishes resistant and susceptible mouse strains

Zhang, H., Adjah, J., Kapse, B., Affinass, N., Ebner, F., Hartmann, S., & Rausch, S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1830307

Parasite‐Derived IL‐33 Inhibitors Prevent Bleomycin‐Induced Lung Fibrosis

Carmine, S. D., Frangova, T. G., Hodge, S. H., Smyth, D. J., Birchall, T., Richards, J., Newton, I. P., Kelly, S. A., Savage, A. R., Cohen, E. S., et al. (2026) · European Journal of Immunology · doi:10.1002/eji.70291

Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of Venom Allergen-Like (VAL) proteins

Hewitson, J. P., Harcus, Y. M., Murray, J., van Agtmaal, M., Filbey, K. J., Grainger, J. R., Bridgett, S., Blaxter, M., Ashton, P. D., Ashford, D. A., et al. (2011) · Journal of Proteomics · doi:10.1016/j.jprot.2011.06.002 · Cited by 160 · see citing works

The production of excretory-secretory molecules from Heligmosomoides polygyrus bakeri fourth stage larvae varies between mixed and single sex cultures

Maruszewska‐Cheruiyot, M., Szewczak, L., Krawczak, K., Głaczyńska, M., & Donskow‐Łysoniewska, K. (2021) · Parasites & Vectors · doi:10.1186/s13071-021-04613-9 · Cited by 19 · see citing works

Proteomic analysis of excretory/secretory products released by Teladorsagia circumcincta larvae early post‐infection

Smith, S. K., Nisbet, A. J., MEIKLE, L. I., Inglis, N. F., Sales, J., Beynon, R. J., & Matthews, J. B. (2008) · Parasite Immunology · doi:10.1111/j.1365-3024.2008.01067.x · Cited by 72 · see citing works

Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection

Hewitson, J. P., Filbey, K. J., Bieren, J. E., Camberis, M., Schwartz, C., Murray, J., Reynolds, L. A., Blair, N. F., Robertson, E., Harcus, Y. M., et al. (2015) · PLoS Pathogens · doi:10.1371/journal.ppat.1004676 · Cited by 99 · see citing works

The immunobiology of Heligmosomoides polygyrus in the murine host

Lawrence, C. E. (1990) · Nottingham ePrints (University of Nottingham)