The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Netherlands Twin Register Biobank: A Resource for Genetic Epidemiological Studies
Open accessAbstract
In 2004 the Netherlands Twin Register (NTR) started a large scale biological sample collection in twin families to create a resource for genetic studies on health, lifestyle and personality. Between January 2004 and July 2008, adult participants from NTR research projects were invited into the study. During a home visit between 7:00 and 10:00 am, fasting blood and morning urine samples were collected. Fertile women were bled on day 2–4 of the menstrual cycle, or in their pill-free week. Biological samples were collected for DNA isolation, gene expression studies, creation of cell lines and for biomarker assessment. At the time of blood sampling, additional phenotypic information concerning health, medication use, body composition and smoking was collected. Of the participants contacted, 69% participated. Blood and urine samples were collected in 9,530 participants (63% female, average age 44.4 (SD 15.5) years) from 3,477 families. Lipid profile, glucose, insulin, HbA1c, haematology, CRP, fibrinogen, liver enzymes and creatinine have been assessed. Longitudinal survey data on health, personality and lifestyle are currently available for 90% of all participants. Genome-wide SNP data are available for 3,524 participants, with additional genotyping ongoing. The NTR biobank, combined with the extensive phenotypic information available within the NTR, provides a valuable resource for the study of genetic determinants of individual differences in mental and physical health. It offers opportunities for DNA-based and gene expression studies as well as for future metabolomic and proteomic projects.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
Saxena, R., Voight, B. F., Lyssenko, V., Burtt, N. P., de Bakker, P. I. W., Chen, H., Roix, J. J., Kathiresan, S., Hirschhorn, J. N., Daly, M. J., et al. (2007) · Science · doi:10.1126/science.1142358 · Cited by 2,843
Scuteri, A., Sanna, S., Chen, W.-M., Uda, M., Albai, G., Strait, J., Najjar, S., Nagaraja, R., Orrú, M., Usala, G., et al. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030115 · Cited by 1,724
Cited by
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
23andMe Research Team, Ferreira, M. A., collaborators, A., BIOS consortium, Study, L. C., Vonk, J. M., Baurecht, H., Marenholz, I., Tian, C., Hoffman, J. D., et al. (2017) · Nature Genetics · doi:10.1038/ng.3985 · Cited by 550
“Information on BMI and current smoking was collected as part of the NTR biobank project 49 at blood draw.”
Self-citationPolygenic risk scores for schizophrenia and bipolar disorder predict creativity
Power, R. A., Steinberg, S., Bjornsdottir, G., Rietveld, C. A., Abdellaoui, A., Nivard, M. M., Johannesson, M., Galesloot, T. E., Hottenga, J. J., Willemsen, G., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.4040 · Cited by 485
Self-citationBroer, L., Codd, V., Nyholt, D. R., Deelen, J., Mangino, M., Willemsen, G., Albrecht, E., Amin, N., Beekman, M., de Geus, E. J. C., et al. (2013) · European Journal of Human Genetics · doi:10.1038/ejhg.2012.303 · Cited by 450
Self-citationHeritability and genomics of gene expression in peripheral blood
Wright, F. A., Sullivan, P. F., Brooks, A. I., Zou, F., Sun, W., Xia, K., Madar, V., Jansen, R., Chung, W., Zhou, Y.-H., et al. (2014) · Nature Genetics · doi:10.1038/ng.2951 · Cited by 362
Self-citationTalens, R. P., Christensen, K., Putter, H., Willemsen, G., Christiansen, L., Kremer, D., Suchiman, H. E. D., Slagboom, P. E., Boomsma, D. I., & Heijmans, B. T. (2012) · Aging Cell · doi:10.1111/j.1474-9726.2012.00835.x · Cited by 300
Self-citation
Metadata
- Authors
- Willemsen, G., de Geus, E. J. C., Bartels, M., van Beijsterveldt, C. E. M. T., Brooks, A. I., Estourgie-van Burk, G. F., Fugman, D. A., Hoekstra, C., Hottenga, J.-J., Kluft, K., Meijer, P., Montgomery, G. W., Rizzu, P., Sondervan, D., Smit, A. B., Spijker, S., Suchiman, H. E. D., Tischfield, J. A., Lehner, T., Slagboom, P. E., & Boomsma, D. I.
- Venue
- Twin Research and Human Genetics
- Publisher
- Cambridge University Press (CUP)
- Published
- 2010-06-01
- Volume
- 13
- Issue
- 3
- Pages
- 231-245
- ISSN
- 1832-4274 (ISSN-L)
- 1839-2628
- OpenAlex
- W2113532105
- Cited by
- 187
- References
- 2
- FWCI
- 6.20
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Netherlands Twin Register Biobank: A Resource for Genetic Epidemiological Studies. https://app.cochat.ai/papers/10.1375/twin.13.3.231
- The paper
- Willemsen, G., de Geus, E. J. C., Bartels, M., van Beijsterveldt, C. E. M. T., Brooks, A. I., Estourgie-van Burk, G. F., Fugman, D. A., Hoekstra, C., Hottenga, J.-J., Kluft, K., Meijer, P., Montgomery, G. W., Rizzu, P., Sondervan, D., Smit, A. B., Spijker, S., Suchiman, H. E. D., Tischfield, J. A., Lehner, T., . . . Boomsma, D. I. (2010). The Netherlands Twin Register Biobank: A Resource for Genetic Epidemiological Studies. Twin Research and Human Genetics. https://doi.org/10.1375/twin.13.3.231
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
