CPAP Titration for Sleep Apnea Using a Split-Night Protocol
Abstract
We studied 107 patients with sleep-disordered breathing to confirm the effectiveness of continuous positive airway pressure (CPAP) titration using a split-night protocol. Patients spent two consecutive nights in our laboratory with complete polysomnography. On the first night, we applied a split-night protocol; the first half of the night was used as a baseline (B), and after a diagnosis was made, CPAP was applied during the second half of the night (SN). On the second night (2N), patients spent the entire night on CPAP to confirm the effectiveness of CPAP treatment. The SN and 2N both revealed a significant reduction in arousal index (37.8 +/- 27.9 on B, 13.2 +/- 12.1 on SN, 11.4 +/- 8.0 on 2N, values are mean +/- SD, p 40, n = 20), the final CPAP pressure was different only in the group with AHI 20.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Three studies compared success of CPAP titration in those undergoing a split-night study against those undergoing a full-night sleep recording.
“Three studies compared success of CPAP titration in those undergoing a split-night study against those undergoing a full-night sleep recording.125,126,128”
From Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline (2017) · cites this paper as [126]
Our literature search yielded nine studies that met inclusion criteria.
“Our literature search yielded nine studies that met inclusion criteria.112,121–128”
From Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline (2017) · cites this paper as [126]
In a cross-over study of patients with OSA, there was no significant difference in AHI, arousal index, and percentage sleep time with oxygen saturation below 90% while on CPAP between split-night and full-night CPAP titration recordings.
“A cross-over study involving comparisons of split-night CPAP recordings versus full-night CPAP titration recordings in patients with OSA, showed no significant difference of the AHI, arousal index and the percentage sleep time with oxygen saturation below 90% while on CPAP, though the final CPAP pressure was lower at the end of the split-night titration (8.8 versus 10.3 cm H2O).126”
From Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline (2017) · cites this paper as [126]
In that cross-over study, the final CPAP pressure was lower at the end of the split-night titration (8.8 versus 10.3 cm H2O).
“A cross-over study involving comparisons of split-night CPAP recordings versus full-night CPAP titration recordings in patients with OSA, showed no significant difference of the AHI, arousal index and the percentage sleep time with oxygen saturation below 90% while on CPAP, though the final CPAP pressure was lower at the end of the split-night titration (8.8 versus 10.3 cm H2O).126”
From Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline (2017) · cites this paper as [126]
Cited by
Sorted by citations
Kapur, V. K., Auckley, D. H., Chowdhuri, S., Kuhlmann, D. C., Mehra, R., Ramar, K., & Harrod, C. G. (2017) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.6506 · Cited by 3,253 · see citing works
Task Force Members, Kushida, C. A., Chediak, A., Berry, R. B., Brown, L. K., Gozal, D., Iber, C., Parthasarathy, S., Quan, S. F., & Rowley, J. A. (2008) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.27133 · Cited by 749 · see citing works
Evaluation of Positive Airway Pressure Treatment for Sleep Related Breathing Disorders in Adults
Gay, P., Weaver, T., Loube, D., & Iber, C. (2006) · Sleep · doi:10.1093/sleep/29.3.381 · Cited by 614 · see citing works
Indications for Positive Airway Pressure Treatment of Adult Obstructive Sleep Apnea Patients
Loube, D. I., Gay, P. C., Strohl, K. P., Pack, A. I., White, D. P., & Collop, N. A. (1999) · Chest · doi:10.1378/chest.115.3.863 · Cited by 363 · see citing works
Split-night versus full-night studies for sleep apnoea/hypopnoea syndrome
McArdle, N., Grove, A., Devereux, G., Mackay-Brown, L., Mackay, T., & Douglas, N. J. (2000) · European Respiratory Journal · doi:10.1034/j.1399-3003.2000.15d08.x · Cited by 84 · see citing works
Clinical presentations of obstructive sleep apnea syndrome
Skomro, R. P., & Kryger, M. H. (1999) · Progress in Cardiovascular Diseases · doi:10.1053/pcad.1999.0410331 · Cited by 78 · see citing works
Self-citationEfficacy and Cost of Home-Initiated Auto-nCPAP versus Conventional nCPAP
Planès, C., D'Ortho, M.-P., Foucher, A., Berkani, M., Leroux, K., Essalhi, M., Delclaux, C., Quera-Salva, M.-A., & Lofaso, F. (2003) · Sleep · doi:10.1093/sleep/26.2.156 · Cited by 68 · see citing works
Patel, N. P., Ahmed, M., & Rosen, I. (2007) · Chest · doi:10.1378/chest.06-1801 · Cited by 36 · see citing works
Bureau, M. P. (2000) · Thorax · doi:10.1136/thorax.55.9.741 · Cited by 23 · see citing works
- Authors
- Yamashiro, Y., & Kryger, M. H.
- Affiliations
- University of Manitoba (CA)
- Corresponding author
- Yamashiro, Yoshihiro
- Venue
- Chest
- Publisher
- Elsevier BV
- Published
- 1995-01
- Volume
- 107
- Issue
- 1
- Pages
- 62-66
- ISSN
- 0012-3692 (ISSN-L)
- OpenAlex
- W2106189167
- Cited by
- 104
- References
- 0
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 1 · 2015: 5 · 2013: 1
- FWCI
- 2.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- CHEST Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Keywords
- continuous positive airway pressure, CPAP titration, sleep apnea, sleep-disordered breathing, apnea-hypopnea index, arousal index, oxygen desaturation, CPAP pressure, polysomnography, treatment effectiveness, daytime sleepiness, sleep efficiency
- MeSH terms
- Female, Humans, Male, Middle Aged, Positive-Pressure Respiration, Sleep Apnea Syndromes, Polysomnography
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
