Sprouty 2 gene in mouse lung tumorigenesis
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SPRY2 negatively regulates Ras/MEK/ERK signaling and is a tumor suppressor in NSCLC in both mice and humans.
“SPRY2, in turn, negatively regulates Ras/MEK/ERK signaling and is a tumor suppressor in NSCLC in both mice (Minowada and Miller, 2004; Minowada and Miller, 2009; Shaw et al., 2007) and humans (Sutterluty et al., 2007).”
From Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21 (2010) · cites this paper as Minowada and Miller, 2004
Cites
Molecular Damage in the Bronchial Epithelium of Current and Former Smokers
Wistuba, I. I., Virmani, A. K., Gazdar, A. F., Lam, S. C., LeRiche, J., Behrens, C., Fong, K. M., Samet, J. M., Srivastava, S., & Minna, J. D. (1997) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/89.18.1366 · Cited by 487 · see citing works
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Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21
Hatley, M. E., Patrick, D. M., Garcia, M. R., Richardson, J. A., Bassel-Duby, R., van Rooij, E., & Olson, E. N. (2010) · Cancer Cell · doi:10.1016/j.ccr.2010.08.013 · Cited by 626 · see citing works
“SPRY2, in turn, negatively regulates Ras/MEK/ERK signaling and is a tumor suppressor in NSCLC in both mice (Minowada and Miller, 2004;Minowada andMiller, 2009; Shaw et al., 2007) and humans (Sutterluty et al., 2007).”
Schaaf, G., Hamdi, M., Zwijnenburg, D. A., Lakeman, A., Geerts, D., Versteeg, R., & Kool, M. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-2532 · Cited by 65 · see citing works
Öngür, D., Pohlman, J., Dow, A. L., Eisch, A. J., Edwin, F., Heckers, S., Cohen, B. M., Patel, T. B., & Carlezon, W. A. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.11.014 · Cited by 56 · see citing works
Overexpression of <i>Sprouty 2</i> in Mouse Lung Epithelium Inhibits Urethane-Induced Tumorigenesis
Minowada, G., & Miller, Y. E. (2009) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2008-0147oc · Cited by 22 · see citing works
Self-citation
- Authors
- Minowada, G., & Miller, Y. E.
- Affiliations
- University Hospitals of Cleveland (US)
- Corresponding author
- Minowada, George
- Venue
- Chest
- Publisher
- Elsevier BV
- Published
- 2004-05
- Volume
- 125
- Issue
- 5
- Pages
- 111S
- ISSN
- 0012-3692 (ISSN-L)
- OpenAlex
- W2093911821
- Cited by
- 4
- References
- 1
- FWCI
- 0.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- CHEST Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
- Health Sciences › Medicine › Oncology › Lung Cancer Research Studies
- Keywords
- Sprouty2, lung carcinogenesis, Ras signaling, tumor suppressor
- MeSH terms
- Animals, Carcinogens, Carcinoma, Non-Small-Cell Lung, Humans, Lung Neoplasms, Membrane Proteins, Proteins, Urethane, Protein Serine-Threonine Kinases, ras Proteins, Intracellular Signaling Peptides and Proteins, Adaptor Proteins, Signal Transducing, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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