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Cited by 71Antifungal resistance and susceptibilityOtolaryngology and Infectious DiseasesNeutropenia and Cancer Infections

Candida Epiglottitis in Immunocompromised Patients

Walsh, Thomas J., Gray, William C.·1987·Chest
DOI 10.1378/chest.91.4.482
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Abstract

Candida seldom has been reported to be a cause of epiglottitis. The clinical manifestations and management of three patients with Candida epiglottitis complicating their neoplastic disease are described. All patients were granulocytopenic. Candida epiglottitis occurred either as a localized infection, as a source of Candida bronchopneumonia, or as a manifestation of disseminated infection. Candida epiglottitis may be under-diagnosed and should be considered, especially in immunocompromised patients with symptoms of refractory pharyngitis. Treatment of Candida epiglottitis with intravenous amphotericin B is warranted in patients with sustained granulocytopenia. Prompt endotracheal intubation is indicated if the airway patency cannot be maintained.

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Crossref · 10.1378/chest.91.4.482

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21 of 21 references verified0 citation errors · 0 not checkable

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  • Data for laryngitis are based on small series and individual case reports.

    “Data for laryngitis are based on small series and individual case reports [177, 178].”

    From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [177]

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Authors
Walsh, T. J., & Gray, W. C.
Affiliations
Johns Hopkins University (US)
Corresponding author
Walsh, Thomas J.
ORCID
Walsh, Thomas J.
Venue
Chest
Publisher
Elsevier BV
Published
1987-04
Volume
91
Issue
4
Pages
482-485
ISSN
0012-3692 (ISSN-L)
DOI
10.1378/chest.91.4.482
OpenAlex
W2047121666
Cited by
71
References
21
Citations by year
2025: 1 · 2024: 2 · 2022: 3 · 2020: 1 · 2018: 3 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 1 · 2012: 1
FWCI
2.91
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • CHEST Journal (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Health Sciences › Medicine › Infectious Diseases › Otolaryngology and Infectious Diseases
  • Health Sciences › Medicine › Oncology › Neutropenia and Cancer Infections
Keywords
candidiasis, immunocompromised patients, granulocytopenia, cancer, systemic candidiasis, amphotericin B, endotracheal intubation, airway management
MeSH terms
Adult, Agranulocytosis, Amphotericin B, Candidiasis, Child, Preschool, Epiglottitis, Female, Humans, Immunologic Deficiency Syndromes, Intubation, Intratracheal, Laryngitis, Laryngoscopy, Male, Middle Aged

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