Medication Adherence Patterns in Chronic Obstructive Pulmonary Disease
Abstract
While medical treatment of COPD has advanced, the failure to adhere to regimens for medication poses a significant barrier to effective management. Furthermore, no data are available regarding adherence for patients within the United States. Data from this investigation indicate that 78 outpatients from a medical center in the southeastern region of the United States were prescribed an average of 6.26 medications with both various dosing schedules and different modes of administration. Adherence was poor, with 42 patients (54 percent) underutilizing medications, 39 patients (50 percent) overutilizing medications during periods of respiratory distress, and 24 patients (31 percent) employing ineffective inhaler dosing techniques. Prescription patterns and adherence were not associated with demographic variables; however, adherence was related to classes of medication and situational variables.
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Treatment adherence may be adversely affected by the use of different drugs and devices, or by inadequate patient education about the illness and associated morbidities from their physician.
“Treatment adherence may also be adversely affected by the use of different drugs and devices, or because patients receive inadequate education about the illness and associated morbidities from their physician [26, 27].”
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“Treatment adherence may also be adversely affected by the use of different drugs and devices, or because patients receive inadequate education about the illness and associated morbidities from their physician [26, 27].”
BackgroundSaja, M., Younis, A., Alzahrani, L., Alkhlassi, I., Aldakhil, L., Albayyat, R., Alnasser, N., Alokla, K., Alghamdi, L., Rashed, A., et al. (2025) · International Journal of Chronic Obstructive Pulmonary Disease · doi:10.2147/copd.s509949 · Cited by 10 · see citing works
- Authors
- Dolce, J. J., Crisp, C., Manzella, B., Richards, J. M., Hardin, J. M., & Bailey, W. C.
- Affiliations
- University of Alabama (US)
- University of Alabama at Birmingham (US)
- Corresponding author
- Dolce, Jeffrey J.
- Venue
- Chest
- Publisher
- Elsevier BV
- Published
- 1991-04
- Volume
- 99
- Issue
- 4
- Pages
- 837-841
- ISSN
- 0012-3692 (ISSN-L)
- OpenAlex
- W2164029912
- Cited by
- 154
- References
- 9
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 9 · 2022: 2 · 2021: 2 · 2020: 3 · 2019: 9 · 2018: 5 · 2017: 7 · 2016: 7 · 2015: 11 · 2014: 7 · 2013: 7 · 2012: 10
- FWCI
- 3.15
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- CHEST Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Keywords
- medication adherence, chronic obstructive pulmonary disease, inhaler technique, prescribing patterns, polypharmacy, respiratory distress, predictors of adherence
- MeSH terms
- Administration, Inhalation, Administration, Oral, Alabama, Ambulatory Care, Bronchodilator Agents, Drug Administration Schedule, Female, Humans, Lung Diseases, Obstructive, Male, Middle Aged, Nebulizers and Vaporizers, Patient Compliance, Self Administration
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