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Automated Structure Solution With autoSHARP

Vonrhein, Clemens, Blanc, Eric, Roversi, Pietro, Bricogne, Gérard·2006·Macromolecular Crystallography Protocols, Volume 2

Abstract

We present here the automated structure solution pipeline "autoSHARP." It is built around the heavy-atom refinement and phasing program SHARP, the density modification program SOLOMON, and the ARP/wARP package for automated model building and refinement (using REFMAC). It allows fully automated structure solution, from merged reflection data to an initial model, without any user intervention. We describe and discuss the preparation of the user input, the data flow through the pipeline, and the various results obtained throughout the procedure.

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Metadata

Authors
Vonrhein, C., Blanc, E., Roversi, P., & Bricogne, G.
Venue
Macromolecular Crystallography Protocols, Volume 2
Publisher
Humana Press
Published
2006-12-16
Volume
364
Pages
215-230
OpenAlex
W2412963709
Cited by
963
References
19
FWCI
222.06
Type
book chapter
Language
en
Open access
closed

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CoChat. (2026). Citation check: Automated Structure Solution With autoSHARP. https://app.cochat.ai/papers/10.1385/1-59745-266-1:215
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Vonrhein, C., Blanc, E., Roversi, P., & Bricogne, G. (2006). Automated Structure Solution With autoSHARP. Macromolecular Crystallography Protocols, Volume 2. https://doi.org/10.1385/1-59745-266-1%3A215

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