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Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

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The Storage and In-Use Stability of mRNA Vaccines and Therapeutics: Not A Cold Case

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Research Advances on the Stability of mRNA Vaccines

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Cleavage of RNA phosphodiester bonds by small molecular entities: a mechanistic insight

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Role of an Active Site Adenine in Hairpin Ribozyme Catalysis

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Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer,

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An imidazole modified lipid confers enhanced mRNA-LNP stability and strong immunization properties in mice and non-human primates

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Metal Ion-Based RNA Cleavage as a Structural Probe

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Oligonucleotide based artificial nuclease (OBAN) systems. Bulge size dependence and positioning of catalytic group in cleavage of RNA-bulges

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Characterization of small interfering RNA by non-denaturing ion-pair reversed-phase liquid chromatography

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PNA based artificial nucleases displaying catalysis with turnover in the cleavage of a leukemia related RNA model

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mRNA Synthesis and Encapsulation in Ionizable Lipid Nanoparticles

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Effect of Ribose Conformation on RNA Cleavage via Internal Transesterification

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Enhanced Complexity and Catalytic Efficiency in the Hydrolysis of Phosphate Diesters by Rationally Designed Helix‐Loop‐Helix Motifs

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Evaluation of Gel-Pad Oligonucleotide Microarray Technology by Using Artificial Neural Networks

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Phosphodiester Cleavage of Ribonucleoside Monophosphates and Polyribonucleotides by Homo‐ and Heterodinuclear Metal Complexes of a Cyclohexane‐Based Polyamino–Polyol Ligand

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Enhanced RNA cleavage within bulge-loops by an artificial ribonuclease

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Effects of the Metal Ion on the Mechanism of Phosphodiester Hydrolysis Catalyzed by Metal-Cyclen Complexes

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The base sequence dependent flexibility of linear single-stranded oligoribonucleotides correlates with the reactivity of the phosphodiester bond

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Base moiety selectivity in cleavage of short oligoribonucleotides by di- and tri-nuclear Zn(II) complexes of azacrown-derived ligands

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Cleavage of a RNA analog containing uridine by a bifunctional dinuclear Zn(II) catalyst

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Not so cold! Improving the thermostability of mRNA vaccines

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Zinc Ion-Dependent Peptide Nucleic Acid-Based Artificial Enzyme that Cleaves RNA—Bulge Size and Sequence Dependence

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Purine Biosynthetic Intermediate-Containing Ribose-Phosphate Polymers as Evolutionary Precursors to RNA

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Stabilisation of the transition state of phosphodiester bond cleavage within linear single-stranded oligoribonucleotides

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Process and analytical strategies for the safe production of mRNA vaccines and therapeutics

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Duplex Formation and the Origins of Homochirality

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Transesterification Reaction and the Repair of Embedded Ribonucleotides in DNA Are Suppressed upon the Assembly of DNA into Nucleosome Core Particles

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Pb 2+ ‐induced Cleavage of RNA

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Structural Modifications as Tools in Mechanistic Studies of the Cleavage of RNA Phosphodiester Linkages

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Site-Selective Artificial Ribonucleases: Oligonucleotide Conjugates Containing Multiple Imidazole Residues in the Catalytic Domain

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Oligonucleotide Based Artificial Ribonucleases (OBANs)

Ghidini, A., Murtola, M., & Strömberg, R. (2014) · Wiley eBooks · doi:10.1002/9781118696880.ch3.2 · Cited by 7

A Fast Catalytic Process of Transfer of a Phosphorus Atom: How Folding of the Reagent is Related to its Catalytic Activity. A Possible Correlation with Rna Behavior

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Bulge-Forming miRNases Cleave Oncogenic miRNAs at the Central Loop Region in a Sequence-Specific Manner

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The Role of Microemulsions in Enhancing the Stability of Biopharmaceuticals

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Hydrolytic Stability of a Phosphate-Branched Oligonucleotide Incorporating a Ribonucleoside 3′-Phosphotriester Unit

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Cleavage of RNA by Imidazole

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Site-Specific Artificial Ribonucleases: Conjugates of Oligonucleotides with Catalytic Groups

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Nonenzymatic and Metal-Ion-Dependent RNA Cleavage, and RNase Models

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Oligonucleotides in Sensing and Diagnostic Applications

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Development of oligonucleotide based artificial ribonucleases 2'-O-MeOBAN´s and PNAzymes

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Messenger RNA for Prophylaxis

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Development, Characterization, and Clinical Evaluation of a 6% Nitroglycerin–Aloe Vera Transdermal Gel for Stable Angina Management

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Fine-scale structural information substantially improves mRNA therapeutic stability prediction

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The cleavage of phosphodiester bonds within small RNA bulges in the presence and absence of metal ion catalysts †

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Cleavage and Isomerization of RNA Phosphodiester Bonds: Nucleoside Phosphotriesters and Chimeric Ribo / 2-O-Methylribo Oligonucleotides as Tools for Mechanistic Studies

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The cleavage of RNA phosphodiester bonds by metal ions

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Structural Modifications as Tools in Mechanistic Studies of the Cleavage of RNA Phosphodiester Linkages

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