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Cited by 68RNA and protein synthesis mechanismsDNA and Nucleic Acid ChemistryPhysical Organic Chemistry and Reaction Kinetics

The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.

The Effect of Secondary Structure on Cleavage of the Phosphodiester Bonds of RNA

Mikkola, Satu, Kaukinen, Ulla, Lönnberg, Harri·2001·Cell Biochemistry and Biophysics

Abstract

This review discusses the effects the secondary structure of an RNA molecule has on the inherent reactivity of its phosphodiester bonds, and on the catalytic activity of metal ion-based cleaving agents. The basic principles of the intramolecular transesterification of RNA phosphodiester bonds, particularly cleavage, are first briefly described. Studies of the structural effects on the cleavage, in the absence and in the presence of metal ion catalysts, are then reviewed, and the sources of the reactivity differences observed in different structures are discussed.

Overview

Integrity signals

Registry

Crossref · 10.1385/cbb:34:1:95

Cites

117 of 117 references verified0 citation errors · 0 not checkable

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Citations

Cites

Cited by

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Metadata

Authors
Mikkola, S., Kaukinen, U., & Lönnberg, H.
Affiliations
University of Turku (FI)
Venue
Cell Biochemistry and Biophysics
Published
2001
Volume
34
Issue
1
Pages
95-119
ISSN
1085-9195 (ISSN-L)
OpenAlex
W1980553137
Cited by
67
References
117
Citations by year
2026: 4 · 2025: 1 · 2024: 4 · 2023: 5 · 2022: 8 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 4
FWCI
1.04
Type
journal article
Language
en
Open access
closed
Locations
  • Cell Biochemistry and Biophysics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
  • Physical Sciences › Chemistry › Organic Chemistry › Physical Organic Chemistry and Reaction Kinetics
Keywords
RNA secondary structure, phosphodiester bond cleavage, metal ion catalysis
MeSH terms
Base Sequence, Catalysis, Chemistry, Physical, Esterification, Hydrogen-Ion Concentration, Metals, Nucleic Acid Conformation, RNA, RNA, Double-Stranded, RNA, Transfer, RNA, Catalytic, Chemical Phenomena

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.