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Cited by 304

The DOI matches its Crossref record; 97 of the 97 references it cites were found in a registry or an index.

Current and Future Treatment of Hepatocellular Carcinoma: An Updated Comprehensive Review

Open access
Daher, Saleh, Massarwa, Muhammad, Benson, Ariel A., Khoury, Tawfik·2018·Journal of Clinical and Translational Hepatology

Abstract

Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related mortality. The principal treatment is surgical resection or liver transplantation, depending on whether the patient is a suitable transplant candidate. However, in most patients with HCC the diagnosis is often late, thereby excluding the patients from definitive surgical resection. Medical treatment includes sorafenib, which is the most commonly used systemic therapy; although, it has been shown to only minimally impact patient survival by several months. Chemotherapy and radiotherapy are generally ineffective. Due to the poor prognosis of patients with HCC, newer treatments are needed with several being in development, either in pre-clinical or clinical studies. In this review article, we provide an update on the current and future medical and surgical management of HCC.

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Registry

Crossref · 10.14218/jcth.2017.00031

Cites

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Metadata

Authors
Daher, S., Massarwa, M., Benson, A. A., & Khoury, T.
Venue
Journal of Clinical and Translational Hepatology
Published
2017-12-17
Volume
6
Issue
1
Pages
1-10
ISSN
  • 2225-0719 (ISSN-L)
  • 2310-8819
OpenAlex
W2774659630
Cited by
304
References
97
FWCI
17.71
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Current and Future Treatment of Hepatocellular Carcinoma: An Updated Comprehensive Review. https://app.cochat.ai/papers/10.14218/jcth.2017.00031
The paper
Daher, S., Massarwa, M., Benson, A. A., & Khoury, T. (2018). Current and Future Treatment of Hepatocellular Carcinoma: An Updated Comprehensive Review. Journal of Clinical and Translational Hepatology. https://doi.org/10.14218/jcth.2017.00031

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.