Cited by 2Protein Hydrolysis and Bioactive PeptidesAntimicrobial Peptides and ActivitiesSeaweed-derived Bioactive Compounds

In Silico Assessment of Photosystem I P700 Chlorophyll a Apoprotein A2 (PsaB) from Chlorella vulgaris (green microalga) as a Source of Bioactive Peptides

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Amin, Md Ariful, Chondra, Uzzal, Alam, Md Morshedul·2024·Journal of Exploratory Research in Pharmacology

Abstract

Chlorella vulgaris is a green, photosynthetic microalga in the phylum Chlorophyta. The goal of our study was to perform a bioinformatics analysis of Photosystem I P700 chlorophyll a apoprotein A2, one of its photosynthesis-related proteins, and to hunt for potent bioactive peptides.

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Crossref · 10.14218/jerp.2023.00030

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  • In silico-directed approaches have gained increasing popularity in recent studies of algal proteins (e.g. Limnospira platensis, Chlorella vulgaris, and Ulva lactuca) to guide discovery faster and maximize specificity of peptide selection.

    “Such in silico-directed approaches have gained increasing popularity in recent studies of algal proteins (e.g. Limnospira platensis, Chlorella vulgaris, and Ulva lactuca) to guide the discovery process faster and maximize the specificity of peptide selection [119,214,215].”

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Research works printed but not linked: 7

  1. Morshedul A. Therapeutic potential of marine bioactive compounds against SARS-CoV2 infection. CPQ Medicine 2020;11(1):1-18.
  2. Chlorella vulgaris with bioactive peptides and their pharmacological relevance. PMID:23056189.
  3. Ramaraj R, Unpaprom Y, Dussadee N. Cultivation of Green Micro- alga , Chlorella Vulgaris for Biogas Purification. Int J New Technol Res 2016;2(3):117-122.
  4. Marr AK, Gooderham WJ, Hancock RE. Antibacterial peptides for therapeutic use: obstacles and realistic outlook. Curr Opin Pharma- col 2006;6(5):468-72. doi:10.1016/j.coph.2006.04.006, PMID:168 90021. · DOI
  5. Fu Y, Young JF, Løkke MM, Lametsch R, Aluko RE, Therkildsen M. Re- valorisation of Bovine Collagen as a Potential Precursor of Angioten- sin I-Converting Enzyme (ACE) Inhibitory Peptides Based on in Silico and in Vitro Protein Digestions. J Functional Foods 2016;24:196-206.
  6. Pooja K, Rani S, Prakash B. In silico approaches towards the explora- tion of rice bran proteins-derived angiotensin-I-converting enzyme inhibitory peptides. Int J Food Properties 2017;20(2):2178-2191.
  7. Kakran M, Li L. Muller RH. Overcoming the challenge of poor drug solubility. Pharm Eng 2012;32(4):1-7.

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Authors
Amin, M. A., Chondra, U., & Alam, M. M.
Affiliations
  • Gono University (BD)
  • North South University (BD)
Venue
Journal of Exploratory Research in Pharmacology
Published
2024-09-30
Volume
000
Issue
000
Pages
000-000
ISSN
2572-5505 (ISSN-L)
OpenAlex
W4403001180
Cited by
2
References
0
Citations by year
2026: 2
FWCI
0.27
Type
journal article
Language
en
Open access
Locations
Journal of Exploratory Research in Pharmacology (publishedVersion, cc-by-nc)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
  • Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Keywords
Chlorella vulgaris, photosystem I, P700, PsaB, bioactive peptides, peptide discovery, photosynthesis-related proteins, green microalgae

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