Role of Hepatitis E Virus Infection in North American Patients With Severe Acute Liver Injury

Fontana, Robert J.; Engle, Ronald E.; Gottfried, Michelle; Hammed, Bilal; Hanje, James; Durkalski, Valerie; Kleiner, David E.; Nguyen, Hanh; Nishimura, Norihisa; Lee, William M.; Farci, Patrizia; for the Acute Liver Failure Study Group

doi:10.14309/ctg.0000000000000273

Role of Hepatitis E Virus Infection in North American Patients With Severe Acute Liver Injury

INTRODUCTION: The aim of this study was to determine the role of hepatitis E virus (HEV) infection in a large cohort of prospectively enrolled patients with severe acute liver injury (ALI). METHODS: Serum samples from 594 consecutive adults enrolled between 2008 and 2018 in the US Acute Liver Fai…